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Mimicking the Plastoquinone-Binding Pocket of Photosystem II Using Molecularly Imprinted Polymers

  • Florent Breton
  • Elena V. Piletska
  • Khalku Karim
  • Régis Rouillon
  • Sergey A. Piletsky
Part of the Biotechnology Intelligence Unit book series (BIOIU)

Abstract

The photosystem II (PSII) is a complex system consisting of at least 10 proteins. The electron-flow events in PSII are mediated via prosthetic groups (plastoquinones QA and QB) bound to two proteins called D1 and D2. A large group of photosynthesis-inhibiting herbicides consisting of arylureas, triazines, triazinones and phenylic herbicides has an ability to replace the plastoquinone QB from its binding pocket located in the D1 protein, interrupting the electron flow between the photosystems and causing the plant’s death. The plastoquinone-binding pocket continues to be a subject of intense research by specialists working on the design and testing of new herbicides, as well as scientists and engineers developing new sensors for herbicide detection. The goal of this review is to analyze the structure of the herbicide-binding pocket of the D 1 protein in comparison to known natural and synthetic receptors of herbicides with the aim of developing efficient synthetic mimics useful in the generation of new stable environmental sensor devices.

Keywords

Electron Paramagnetic Resonance Methacrylic Acid Itaconic Acid Functional Monomer Imprint Polymer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Landes Bioscience 2006

Authors and Affiliations

  • Florent Breton
    • 1
  • Elena V. Piletska
    • 2
  • Khalku Karim
    • 2
  • Régis Rouillon
    • 1
  • Sergey A. Piletsky
    • 2
  1. 1.Centre de PhytopharmacieUniversité de PerpignanPerpignanFrance
  2. 2.Institute of Bioscience and TechnologyCranfield UniversitySilsoe, BedforshireUK

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