Abstract
Carcinoma of the lung is a common malignant tumor. Histological typing of lung tumors has long been a source of controversy in pathology, in large part due to the marked heterogeneity that these tumors are capable of exhibiting (1–4). Although the bronchi and lungs may give rise to a wide variety of histopathologic types of malignant epithelial neoplasms, lung cancer grading is usually restricted to the 2 most common types of bronchogenic carcinoma included in the latest World Health Organization (WHO) classification: squamous cell carcinoma and adenocarcinoma. Neuroendocrine carcinoma of the lung constitutes a third major group of lung neoplasms for which grading is promising, as the histologic grading of these tumors appears to correlate with their clinical behavior and prognosis (5). The fourth major category of bronchogenic carcinoma in the WHO classification, large cell carcinoma, is not subject to grading, since it is by definition a high-grade neoplasm.
Keywords
Malignant Mesothelioma Neuroendocrine Carcinoma Large Cell Carcinoma Bronchogenic Carcinoma Atypical CarcinoidPreview
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