Effects of Taurine Supplementation on Cholesterol Levels with Potential Ramification in Atherosclerosis
It is quite convincing from the literature that taurine supplemented in the diet and administered to various animal models (rat, mouse, and rabbit) has a significant effect in reducing both total cholesterol and the induced atherogenic lesions. Unfortunately, there are very few studies in which taurine has been administered to humans. Because of the present prevalence of high fat diets in our society and the serious sequellae associated with high serum cholesterol levels, it is considered after reviewing the data in the literature that more studies are needed to access the value of supplemental dietary taurine in the human model. If truly beneficial in lowering human hypercholesterol levels, taurine could be an inexpensive, nontoxic dietary supplement with significant cardiovascular properties.
KeywordsBile Acid Gallstone Formation High Cholesterol Diet Atherogenic Index Sodium Cholate
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- Nishimura, N., Umeda, C., Oda, H., and Yokogoshi, H., 2003, The effect of taurine on the cholesterol metabolism in rats fed diets supplemented with cholestyramine or high amounts of bile acid. J. Nutr. Sci. Vitaminol. (Tokyo), 49:21–26.Google Scholar