Pediatric Sedation Outside of the Operating Room

pp 77-91


Pediatric Physiology: How Does it Differ from Adults?

  • Dean B. AndropoulosAffiliated withDivision of Pediatric Cardiovascular Anesthesiology, Department of Anesthesiology, Texas Children’s HospitalDepartments of Anesthesiology and Pediatrics, Baylor College of Medicine Email author 

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Safe sedation of pediatric patients requires a thorough understanding of the physiological differences between infants, children, adolescents, and adults. Especially in small infants, there is much less margin for any errors in diagnosis and treatment of respiratory or cardiovascular depression during sedation procedures. This chapter will review developmental aspects of respiratory, cardiovascular, central nervous system, renal, hepatic, hematologic, and temperature homeostatic systems, highlighting the differences between children and adults and emphasizing their relevance to sedation procedures in children.