Pediatric Physiology: How Does it Differ from Adults?



Safe sedation of pediatric patients requires a thorough understanding of the physiological differences between infants, children, adolescents, and adults. Especially in small infants, there is much less margin for any errors in diagnosis and treatment of respiratory or cardiovascular depression during sedation procedures. This chapter will review developmental aspects of respiratory, cardiovascular, central nervous system, renal, hepatic, hematologic, and temperature homeostatic systems, highlighting the differences between children and adults and emphasizing their relevance to sedation procedures in children.


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© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  1. 1.Division of Pediatric Cardiovascular Anesthesiology, Department of AnesthesiologyTexas Children’s HospitalHoustonUSA
  2. 2.Departments of Anesthesiology and PediatricsBaylor College of MedicineHoustonUSA

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