The Coronin Family of Proteins

  • Christoph S. Clemen
  • Vasily Rybakin
  • Ludwig Eichinger
Part of the Subcellular Biochemistry book series (SCBI, volume 48)

Abstract

The coronins, first described in Dictyostelium discoideum in 1991, have meanwhile been detected in all eukaryotes except plants. They belong to the superfamily of WD40-repeat proteins and represent a large family of proteins, which are often involved in cytoskeletal functions. Phylogenetic studies clearly distinguish 12 subfamilies of which six exclusively occur in vertebrates. In the present book we have made a sincere attempt to provide a comprehensive overview on all aspects of coronin proteins including history, structure, subcellular localization and function in different organisms. In addition, we also included a general overview on the WD40 family of proteins and the structurally related Kelch family. The book should be of interest for scientists outside the field, but is more importantly intended as a fast and competent guide for newcomers as well as doctoral and postdoctoral scientists to coronin research in all its facets.

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Copyright information

© Landes Bioscience and Springer Science+Business Media 2008

Authors and Affiliations

  • Christoph S. Clemen
    • 2
  • Vasily Rybakin
    • 1
  • Ludwig Eichinger
    • 2
  1. 1.The Scripps Research InstituteLa JollaUSA
  2. 2.Center for Biochemistry, Medical FacultyUniversity of CologneCologneGermany

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