Behavioral Neurobiology of Eating Disorders

Volume 6 of the series Current Topics in Behavioral Neurosciences pp 253-268


Translating Experimental Neuroscience into Treatment of Eating Disorders: Two Examples

  • Ulrike SchmidtAffiliated withSection of Eating Disorders, King’s College London, Institute of Psychiatry Email author 
  • , Anna OldershawAffiliated withSection of Eating Disorders, King’s College London, Institute of Psychiatry
  • , Annemarie van ElburgAffiliated withRintveld Center for Eating Disorders, Altrecht Mental Health InstituteDepartment of Child and Adolescent Psychiatry, University Medical Center

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Anorexia nervosa (AN) is a serious mental disorder with impaired functioning including not only the cognitive and socio-emotional but also physical domains. Improved treatments, especially for adults with AN, are urgently needed. The insights gained from basic research in experimental animal models and the advent of cognitive neuroscience have produced major advances in our understanding of the condition, but translating these into clinical research or practice remains a challenge. We describe here what the eating disorders field can gain from schizophrenia research in this area. We use the example of socio-emotional impairments in AN to describe the iterative process between basic research and intervention development for neurobiologically informed and based treatments for this condition and briefly touch on some other examples that stem from translational science.


Anorexia neruosa Translational research Social cognition