Control of Biofilm Infections by Signal Manipulation

Volume 2 of the series Springer Series on Biofilms pp 1-11



  • Naomi BalabanAffiliated withCummings School of Veterinary Medicine, Department of Biomedical Sciences, Division of Infectious Diseases, Tufts University Email author 
  • , Dacheng RenAffiliated withDepartment of Biomedical and Chemical Engineering, Syracuse University
  • , Michael GivskovAffiliated withBioCentrum-DTU, Technical University of Denmark
  • , Thomas Bovbjerg RasmussenAffiliated withInnovation, Cultures & Enzymes Division

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This introductory chapter discusses the problem of drug resistance and persistent medical biofilm infections, emphasizing the need for alternative approaches to the prevention and treatment of biofilm infections. Such alternative approaches are described in subsequent chapters, culminating with clinical studies that describe treating otherwise untreatable wound infections with the aid of antibiofilm approaches.