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Free Radicals in Heterocycle Functionalization

  • Jomy Joseph
  • Andrey P. Antonchick
Chapter
Part of the Topics in Heterocyclic Chemistry book series (TOPICS, volume 54)

Abstract

Functionalization of heterocycles through free radical intermediates has been widely employed in a diverse array of synthetic transformations. This chapter focuses on the recent developments in the light-assisted as well as traditional free radical generation methodology and the subsequent utilization in functionalization of various heterocycles.

Keywords

Alkylation Arylation Cross-dehydrogenative coupling Free radicals Heterocycles Minisci reaction Photocatalysis 

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Authors and Affiliations

  1. 1.Department of Chemical BiologyMax-Planck Institute for Molecular PhysiologyDortmundGermany
  2. 2.Department of Chemistry and Chemical BiologyTechnische Universität DortmundDortmundGermany

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