pp 1-14 | Cite as

Potential of Tribological Properties of Metal Nanomaterials in Biomedical Applications

  • Pravin ShendeEmail author
  • Drashti Patel
Part of the Advances in Experimental Medicine and Biology book series


Metallic nanomaterials show tremendous applications in biomedical devices due to compatible integration into the most of the biological systems as they are nano- structured. Metallic nanomaterials are capable of mimicking all the three major antioxidant enzymes such as catalase (CAT), peroxidase and oxidase, to control the level of reactive oxygen species (ROS) inside the cell as an alternative strategy over conventional one which has biological toxicity and have several adverse effects, if accumulation takes places during the treatment. This anti-oxidant property of metallic nanomaterials demonstrates as a promising candidate for its biomedical application in disease conditions where the excessive level of ROS causes damage to DNA, lipids and protein in several conditions such as diabetes, cancer and neurodegenerative diseases. Tribology is the study of interacting surfaces in motion and the measurement of properties such as friction, wear-tear and abrasion. While designing nano-scale biomedical devices, the consideration of tribology is particularly important because the high surface area ratio enhances problems with friction and wear-tear which can further affects its function as well as longevity.

Graphical Abstract


Biomedical application Metallic nanomaterial Tribological testing Tribology 



Alzheimer’s disease

Amyloid beta




Regulation concerning Classification, Labeling and Packaging of Substances and Mixtures


Epidermal growth factor


fibroblast growth factor


Large Surface Area Plasmon resonance


Manganese oxide


Polybutylcyanoacrylate polymer-Titanium/Aluminum


Platelet-derived growth factor


Registration, Evaluation, Authorization and Restrictions of Chemicals


Reactive oxygen species


Surface-enhanced Raman Scattering


Substantial Nigra pars Compacta


Significant New Use Rules


Toxic Substance Control Act


Vascular endothelial growth factor


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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Shobhaben Pratapbhai Patel School of Pharmacy and Technology ManagementSVKM’S NMIMSMumbaiIndia

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