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Biochemistry of Oxidative Stress

  • Michał P. Pruchniak
  • Magdalena Araźna
  • Urszula Demkow
Chapter
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 878)

Abstract

Generation of reactive oxygen species is a physiological process that take place in every aerobic organism. Oxidative stress is defined as a disturbance in the balance between the production of free radicals and antioxidants in favor of the oxidants. The imbalance between those two fractions may potentially lead to cell damage at molecular level. Since oxidants are formed at a different rate as a normal product of aerobic metabolism, complex biochemical mechanisms are required to regulate the entire process.

Keywords

Antioxidation Free radicals Oxidative stress Reactive oxygen species Reactive nitrogen species 

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Copyright information

© Springer International Publishing Switzerland 2015

Authors and Affiliations

  • Michał P. Pruchniak
    • 1
    • 2
  • Magdalena Araźna
    • 1
  • Urszula Demkow
    • 1
  1. 1.Department of Laboratory Diagnostic and Clinical Immunology of Developmental AgeMedical University of WarsawWarsawPoland
  2. 2.Postgraduate School of Molecular MedicineWarsawPoland

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