A Survey of Graphene-Based Field Effect Transistors for Bio-sensing

  • Cy R. TamanahaEmail author
Part of the Springer Series on Chemical Sensors and Biosensors book series (SSSENSORS, volume 17)


There have been numerous investigations to implement graphene’s unique electronic and physical characteristics in devices ranging from batteries to reinforced structures. This chapter surveys the significant effort that has been made to successfully integrate graphene into a practical, cheap, highly sensitive biosensor. The biologically active field effect transistor (BioFET) is a class of biosensors based on ion selective FET (ISFET) technology which operates on the detection of charged molecules; when a charged molecule is present, changes in the electrostatic field at the BioFET transducing surface result in a measurable change in current through the transistor (Schoning and Poghossian, Analyst 127:1137–1151, 2002). The chapter titled “Graphene-Based Chemical and Biosensors,” in Volume 14 of the Springer Series on Chemical Sensors and Biosensors, provided a comprehensive look at the chemical and electrochemical aspects of graphene-based chemical sensors (Wisitsoraat A and Tuantranont A, Graphene-based chemical and biosensors. In: Tuantranont A (ed) Applications of nanomaterials in sensors and diagnostics. Springer, Berlin Heidelberg, pp. 103–141, 2013). In the present chapter of the same series, we supplement that excellent work with the current state of graphene-based field effect transistors (FET), and concentrate on graphene’s high sensitivity to changes in electric fields for sensing biomolecules such as DNA, proteins, and neurotransmitters.


BioFET Bio-sensing Field effect transistor Graphene 


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© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.U.S. Naval Research LaboratoryWashingtonUSA

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