Molecular Genetics of Recombination pp 381-442

Part of the Topics in Current Genetics book series (TCG, volume 17)

Meiotic recombination

Chapter

Abstract

Crossover recombination is essential for homolog segregation during meiosis. In contrast to spontaneous mitotic recombination, meiotic recombination is intrinsic being initiated by the programmed formation of DNA double-strand-breaks. In addition, the tendencies of the core recombination machinery to utilize a sister-chromatid template and to produce a noncrossover outcome are counteracted by meiosis-specific factors, which ultimately ensure the formation of at least one crossover per homolog.

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© Springer-Verlag Berlin Heidelberg 2006

Authors and Affiliations

  1. 1.Sections of Microbiology and Molecular & Cellular BiologyUniversity of California DavisDavisUSA

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