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Production of extracellular microbial polysaccharides

  • Gary W. Pace
  • Renton C. Righelato
Conference paper
Part of the Advances in Biochemical Engineering book series (ABE, volume 15)

Abstract

Over the past twenty years a new class of microbial products, the microbial polysaccharides, has grown in industrial importance. These products can be used as alternatives to other synthetic or natural water soluble polymers or as novel polymers in thickening, suspending and gelling applications. In this article we review the technology of the production of extracellular microbial polysaccharides with particular emphasis on the characteristics and problems associated with handling highly viscous non-Newtonian culture fluids.

Keywords

Apparent Viscosity Sherwood Number Impeller Speed Azotobacter Vinelandii Guluronic Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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10 References

  1. 1.
    Sutherland, I.W.: Surface carbohydrates of the prokaryotic cell, p. 27. London: Academic Press 1977Google Scholar
  2. 2.
    Jarman, T.R., Deavin, L., Slocombe, S., Righelato, R.C.: J. Gen. Microbiol. 107, 59 (1978)Google Scholar
  3. 3.
    Laskin, A., Lechevalier, H.: Handbook microbiology, condensed Edit., p. 680. Cleveland, Ohio: C. R. C. 1974Google Scholar
  4. 4.
    Johnson, J., Kirkwood, S., Misaki, A., Nelson, T.E., Scaletti, J.V., Smith, F.: Chem. Ind., p. 820, 1963Google Scholar
  5. 5.
    Harada, T.: Fermentation technology today: Proc. 4 th Internat. Fermentation Symposium, p. 603, 1972Google Scholar
  6. 6.
    Jansson, P.E., Keene, L., Lindberg, B., Ljunggren, H., Lonngren, J., Ruden, U., Svensson, S.: J. Am. Chem. Soc. 11, 3812 (1977)Google Scholar
  7. 7.
    Cadmus, M.C., Knutson, C.A., Lagoda, A.A., Pittsley, J.E., Burton, K.A.: Biotech. Bioeng. 20, 1003 (1978)Google Scholar
  8. 8.
    Davidson, I.W., Sutherland, I.W., Lawson, C.J.: J. Gen. Microbiol. 98, 603 (1977)Google Scholar
  9. 9.
    Rees, D.A.: Chem. and Ind., p. 630 (1972)Google Scholar
  10. 10.
    Deavin, L., Jarman, T.R., Lawson, C.J., Righelato, R.C.: In: Extracellular microbial polysaccharides. Sandford, P.A., Laskin, A. (eds.), p. 14. Am. Chem. Soc., Washington, D.C. 1977Google Scholar
  11. 11.
    Gibbons, R.J., Nygaard, M.: Arch. Oral Biology 13, 1249 (1968)Google Scholar
  12. 12.
    Lawson, C.J., Sutherland, I.W.: Economic microbiology, Vol. 2. New York: Academic Press 1978Google Scholar
  13. 13.
    Bucke, C: Chromatography 89, 99 (1974)Google Scholar
  14. 14.
    Sutherland, I.W.: Soc. Gen. Microbiol. Proc., p. 107, 1978Google Scholar
  15. 15.
    Holzwarth, G.: Carbohydrate Res. 66, 171 (1978)Google Scholar
  16. 16.
    Jeanes, A.R., Sloneker, J.H.: U.S. Pat. 3,054, 689 (1962)Google Scholar
  17. 17.
    Sandford, P.A., Pittsley, J.E., Knutson, C.A., Watson, P.R., Cadmus, M.C., Jeanes, A.: In: Extracellular microbial polysaccharides. Sandford, P.A., Laskin, A. (eds.), p. 192. Am. Chem. Soc., Washington D.C. 1977Google Scholar
  18. 18.
    Haug, A., Larsen, B.: Carbohydrate Res. 17, 297 (1971)Google Scholar
  19. 19.
    Larsen, B., Haug, A.: Carbohydrate Res. 17, 287 (1971)Google Scholar
  20. 20.
    Pindar, D.F., Bucke, C: Biochem. J. 152, 617 (1975)Google Scholar
  21. 21.
    Sutherland, I.W.: In: Extracellular microbial polysaccharides. Sandford, P.A., Laskin, A. (eds.), p. 40. Am. Chem. Soc., Washington, D.C. 1977Google Scholar
  22. 22.
    Neijssel, O.M., Tempest, D.W.: Arch. Microbiology 107, 215 (1976)Google Scholar
  23. 23.
    Williams, A.G.: Extracellular polysaccharide production by a gram-negative bacterial isolate. Ph. D. thesis, University of Wales 1974Google Scholar
  24. 24.
    Silman, R.W., Rogovin, S.P.: Biotech. Bioeng. 14, 23 (1972)Google Scholar
  25. 25.
    Mian, F., Jarman, T.R., Righelato, R.C.: J. Bact. 134, 418 (1978)Google Scholar
  26. 26.
    Davidson, I.W.: FEMS Microbiology Lett. 3, 347 (1978)Google Scholar
  27. 27.
    Williams, A.G., Wimpenny, J.W.T.: J. Gen. Microbiol. 104, 47 (1978)Google Scholar
  28. 28.
    Ellwood, D.C, Evans, C.G.T., Yeo, R.G.: U.K. Pat. 1512 536 (1978)Google Scholar
  29. 29.
    Harada, T., Yoshimura, T., Hidaka, H., Koreeda, A.: Agricult. Biol. Chem. 29, 757 (1965)Google Scholar
  30. 30.
    Evans, L.R., Linker, A.: J. Bact. 116, 915 (1973)Google Scholar
  31. 31.
    Wilkinson, J.F., Duguid, J.P., Edmunds, P.N.: J. Gen. Microbiol. 11, 59 (1954)Google Scholar
  32. 32.
    Silman, R.W., Rogovin, P.: Biotech. Bioeng. 12, 75 (1970)Google Scholar
  33. 33.
    Moraine, R.A., Rogivin, P.: Biotech. Bioeng. 15, 225 (1973)Google Scholar
  34. 34.
    Godet, P.: Proc. Biochemistry 8 (1), 33 (1973)Google Scholar
  35. 35.
    McNeely, W.J.: U.S. Pat. 3391060 (1969)Google Scholar
  36. 36.
    Lindblom, G.P., Patton, J.: U.S. Pat. 3328262 (1967)Google Scholar
  37. 37.
    Tong, G.: Int. Biochem. Symp. Stone and Webster Canada Limited 1977Google Scholar
  38. 38.
    Jeanes, A.: Food Technol. 28, 34 (1974)Google Scholar
  39. 39.
    Jeanes, A.: J. Polymer Sci.: Symposium No. 45, 209 (1974)Google Scholar
  40. 40.
    Catley, B.J.: FEBS Letters 20, 174 (1972)Google Scholar
  41. 41.
    Hofheinz, W., Grisebach, H.: Chem. Ber. 96, 2867 (1963)Google Scholar
  42. 42.
    Adams, G.A., Martin, S.M.: Can. J. Biochem. 42, 1403 (1964)Google Scholar
  43. 43.
    Simley, K.L.: Food Technol. 20, 112 (1966)Google Scholar
  44. 44.
    Spencer, J.F.T., Gorin, P.A.J.: Biotechnol. Bioeng. 15, 1 (1973)Google Scholar
  45. 45.
    Farr, D.R., Armister, H., Horisberger, M.: Carbohydrate Res. 24, 207 (1972)Google Scholar
  46. 46.
    Blakebrough, N., McMananey, W.J., Tart, K.R.: Trans. IChemE, 56, 127 (1978)Google Scholar
  47. 47.
    Leduy, A., Marsan, A.A., Coupal, B.: Biotechnol. Bioeng. 16, 61 (1974)Google Scholar
  48. 48.
    Miura, Y., Fukushima, S., Sambuichi, M., Ueda, S.: J. Ferment Technol. 54, 166 (1976)Google Scholar
  49. 49.
    Whitcomb, P.J., Ek, B.J., Macosko, C.W.: In: Extracellular microbial polysaccharides. Sandford, P.A., Laskin, A. (eds.), p. 160. Am. Chem. Soc., Washington D.C. 1977Google Scholar
  50. 50.
    Elliott, J.E.: In: Extracellular microbial polysaccharides. Sandford, P.A., Laskin, A. (eds.), p. 144. Am. Chem. Soc., Washington D.C. 1977Google Scholar
  51. 51.
    Charles, M.E.: In: Adv. Biochem. Eng. Ghose, T.K., Fiechter, A., Blakebrough, N. (eds.), Vol. 8, p. 1. Berlin, Heidelberg, New York: Springer 1978Google Scholar
  52. 52.
    Holzwarth, G.: Biochemistry 15, 4333 (1976)Google Scholar
  53. 53.
    Tako, M., Nagahama, T., Nomura, D.: J. Agric. Chem. Soc. (Japan) 51, 513 (1977)Google Scholar
  54. 54.
    Bhavaraju, S.M., Russell, T.W.F., Blanch, H.W.: AIChEJ 24, 454 (1978)Google Scholar
  55. 55.
    Lipps, B.J.: U.S. Pat. 3,281,329 (1966)Google Scholar
  56. 56.
    Bates, R.L., Fondy, P.L., Fenic, J.G.: Mixing. Uhl, V.W., Gray, J.B. (eds.), Vol. 1. New York: Academic Press 1966Google Scholar
  57. 57.
    Holland, F.A., Chapman, F.S.: Liquid mixing and processing in stirred tank. New York: Reinhold 1966Google Scholar
  58. 58.
    Metzner, A.B., Feehs, R.H., Ramos, H.L., Otto, R.E., Tuthill, J.D.: AIChEJ 7, 3 (1961)Google Scholar
  59. 59.
    Metzner, A.B., Otto, R.E.: AIChEJ 3, 3 (1957)Google Scholar
  60. 60.
    Nagata, S.: Mixing principles and applications. New York: John Wiley and Sons 1975Google Scholar
  61. 61.
    Aiba, S., Humphrey, A.E., Millis, N.F.: Biochem. Eng. New York: Academic Press 1973Google Scholar
  62. 62.
    Calderbank, P.H., Moo-Young, M.B.: Trans. IChemE 99, 337 (1961)Google Scholar
  63. 63.
    Ranade, V.R., Ulbrecht, J.: Proc. Soc. Europ. Conf. on Mixing. Paper F6 Cambridge, England 1977Google Scholar
  64. 64.
    Van't Riet, K.: Turbine agitation hydrodynamics and dispersion performance. PhD Thesis, Delft Univers. 1975Google Scholar
  65. 65.
    Oyama, Y., Endoh, K.: Chem. Eng. (Japan) 19, 2 (1955)Google Scholar
  66. 66.
    Michel, B.J., Miller, S.A.: AIChEJ 8, 262 (1962)Google Scholar
  67. 67.
    Taguchi, H., Miyamoto, S.: Biotech. Bioeng. 8, 43 (1966)Google Scholar
  68. 68.
    Bruijn, W., Van't Riet, K., Smith, J.M.: Trans. IChemE 52, 88 (1974)Google Scholar
  69. 69.
    Edney, H.G.S., Edwards, M.F.: Trans. IChemE 54, 160 (1976)Google Scholar
  70. 70.
    Oldshue, J.: Biotech. Bioeng. 8, 3 (1966)Google Scholar
  71. 71.
    Uhl, V.W., Gray, J.B.: Mixing. Vols. 1 and 2. New York: Academic Press 1966Google Scholar
  72. 72.
    Johnson, D.N., Hubbard, D.W.: Biotech. Bioeng. 16, 1283 (1974)Google Scholar
  73. 73.
    Hubbard, D.W., Williams, C.N.: Process Biochem. 12 (10), 11 (1977)Google Scholar
  74. 74.
    Giacobbe, F., Capobianco, G.: Paper presented Soc. Gen. Microbiol. Meeting. Reading, England, Sept. 1976Google Scholar
  75. 75.
    Moraine, R.A., Rogovin, P.: Biotech. Bioeng. 15, 225 (1973)Google Scholar
  76. 76.
    Giesekus, H.: Rheol Acta 4, 85 (1965)Google Scholar
  77. 77.
    Ulbrecht, J.: The chem. Eng., p. 347. London 1974Google Scholar
  78. 78.
    White, J.L., Chankraiphon, S., Ide, Y.: Trans. Soc. Rheol. 21, 1 (1977)Google Scholar
  79. 79.
    Chavan, V.V., Arumugan, M., Ulbrecht, J.: AIChEJ 21, 613 (1975)Google Scholar
  80. 80.
    Paca, J., Ettler, P., Gregr, V.: J. Appl. Chem. Biotech. 26, 309 (1976)Google Scholar
  81. 81.
    Hattori, K., Yokoo, S., Imada, O.: J. Ferment: Technol. 50, 737 (1976)Google Scholar
  82. 82.
    Perez, J.F., Sandall, O.C.: AIChEJ 20, 770 (1974)Google Scholar
  83. 83.
    Yagi, H., Yoshida, F.: Ind. Eng. Chem. Process Des. Dev. 14, 488 (1975)Google Scholar
  84. 84.
    Astarita, G., Mashelkar, R.A.: The Chem. Eng., p. 100, 1977Google Scholar
  85. 85.
    Mashelkar, R.A., Soylu, M.A.: Chem. Eng. Sci. 29, 1089 (1974)Google Scholar
  86. 86.
    Astarita, G., Apuzzo, G.: AIChEJ 11, 815 (1965)Google Scholar
  87. 87.
    Nakano, Y., Tien, G.: AIChEJ 14, 145 (1968)Google Scholar
  88. 88.
    Hirose, T., Moo-Young, M.: Can. J. Chem. Eng. 47, 265 (1969)Google Scholar
  89. 89.
    Wellek, R.M., Huang, C.C.: Ind. Eng. Chem. Fundam. 9, 480 (1970)Google Scholar
  90. 90.
    Acharya, A., Mashelkar, R.A., Ulbrecht, J.: Chem. Eng. Sci. 32, 863 (1972)Google Scholar
  91. 91.
    Bhavaraju, S.M., Mashelkar, R.A., Blanch, H.W.: AIChEJ 24, 1063 (1978)Google Scholar
  92. 92.
    Bhavaraju, S.M., Mashelkar, R.A., Blanch, H.W.: AIChEJ 24, 1070 (1978)Google Scholar
  93. 93.
    Calderbank, P.H., Johnson, D.S.L., London, J.: Chem. Eng. Sci. 25, 235 (1970)Google Scholar
  94. 94.
    Acharya, A., Ulbrecht, J.J.: AIChEJ 24, 348 (1978)Google Scholar
  95. 95.
    deNevers, N., Wu, J.L.: AIChEJ 17, 182 (1971)Google Scholar
  96. 96.
    Narayanan, S., Goossens, L.H.J., Kossen, N.W.F.: Chem. Eng. Sci. 29, 2071 (1974)Google Scholar
  97. 97.
    King, M.L., Russell, T.W.F., Blanch, H.W.: Paper presented at Meeting of Am. Chem. Soc., Miami, Florida, Sept. 11, 1978Google Scholar
  98. 98.
    Edwards, M.F., Wilkinson, W.L.: The Chem. Eng., p. 310. London 1972Google Scholar
  99. 99.
    Edwards, M.F., Wilkinson, W.L.: The Chem. Eng., p. 328. London 1972Google Scholar
  100. 100.
    Rao, K.B., Murti, P.S.: Ind. Eng. Chem. Process Des. Develop. 13, 190 (1973)Google Scholar
  101. 101.
    Pollard, R., Topiwala, H.H.: Biotech. Bioeng. 18, 1517 (1976)Google Scholar
  102. 102.
    Sucher, R.W., Robbins, E.A., Schuldz, E.H., Seeley, R.D., Newell, J.A.: 33rd Ann. Meeting of Institute of Food Technologists Miami, Florida 1973Google Scholar
  103. 103.
    Jeanes, A.: In: Encyclopedia of polymer science and technology, Vol. 8. New York: John Wiley and Sons 1968Google Scholar
  104. 104.
    Leader, H.J., Miescher, G.M.: U.S. Pat. 3,316,241 (1967)Google Scholar
  105. 105.
    Mehltretter, C.L.: Biotech. Bioeng. 7, 171 (1965)Google Scholar
  106. 106.
    McNeely, W.J.: U.S. Pat. 3,232,929 (1966)Google Scholar
  107. 107.
    Patton, J.H., Holman, W.F.: U.S. Pat. 3,382,229 (1968)Google Scholar
  108. 108.
    Falcoz, P., Celle, P., Campagne, J.C.: French Pat. 2,299,366 (1976)Google Scholar
  109. 109.
    Cahalan, P.T., Peterson, J.A., Arudt, D.A.: U.S. Pat. 4,053,699 (1977)Google Scholar
  110. 110.
    Towle, G.A.: U.S. Pat. 4,051,317 (1977)Google Scholar
  111. 111.
    Albrect, W.J., Sohns, V.E., Rogovin, S.P.: Biotech. Bioeng. 5, 91 (1963)Google Scholar
  112. 112.
    Rogovin, S.P., Albrecht, W.J.: U.S. Pat. 3,119,812 (1964)Google Scholar
  113. 113.
    Jordan, W.A., Carter, W.H.: U.S.Pat. 3,928,316 (1975)Google Scholar
  114. 114.
    Rogovin, P., Albrecht, W., Sohns, V.: Biotech. Bioeng. 7, 161 (1965)Google Scholar
  115. 115.
    Bouniot, A.: U.S. Pat. 3,988,313 (1976)Google Scholar
  116. 116.
    Abdo, M.K.: U.S. Pat. 3,711,462 (1973)Google Scholar
  117. 117.
    Buchanan, B.B., Cottle, J.E.: Pat. 3,773,752 (1973)Google Scholar
  118. 118.
    O'Connell, J.: U.S. Pat. 3,355,447 (1967)Google Scholar
  119. 119.
    Patton, J.T., Holman, W.E.: U.S. Pat. 3,208,526 (1965)Google Scholar
  120. 120.
    Rogovin, S.P., Anderson, R.F., Cadmus, M.C.: Biotech. Bioeng. 3, 51 (1961)Google Scholar
  121. 121.
    Colegrove, G.T.: U.S. Pat. 3,966,618 (1976)Google Scholar
  122. 122.
    Patton, J.T.: U.S. Pat. 3,964,972 (1976)Google Scholar
  123. 123.
    Colegrove, G.T.: U.S. Pat. 3,516,983 (1970)Google Scholar
  124. 124.
    Colin, P., Guibert, V.: U.S. Pat. 3,591,578 (1971)Google Scholar
  125. 125.
    Larsen, B., Haug, A.: Carbohydrate Res. 17, 287 (1971)Google Scholar
  126. 126.
    Empey, R.A.: U.S. Pat. 4,070,535 (1978)Google Scholar
  127. 127.
    Rao, P.S., Srivastava, S.: In: Industrial gums. Whistler, R.L. (ed.). New York: Academic Press 1973Google Scholar
  128. 128.
    Maske, F.J.: U.S. Pat. 4,041,234 (1977)Google Scholar
  129. 129.
    Jeanes, A.R., Sloneker, J.H.: U.S. Pat. 3,096,293 (1963)Google Scholar
  130. 130.
    Patton, J.T.: U.S. Pat. 3,020,207 (1962)Google Scholar
  131. 131.
    Stratton, C.A.: U.S. Pat. 3,844,348 (1974)Google Scholar
  132. 132.
    Selby, H.W., Wynne, W.H.: In: Industrial gums. Whistler, R.L. (ed.). New York: Academic Press 1973Google Scholar
  133. 133.
    McNeely, W.H., Pettitt, D.J.: In: Industrial gums. Whistler, R.L. (ed.). New York: Academic Press 1973Google Scholar
  134. 134.
    Taiho Industrial Co., Ltd.: Brit. Pat. 856,416, 1962; Chem. Abstr. 62, 4654, 1965Google Scholar
  135. 135.
    Towle, G.A.: In: Industrial gums. Whistler, R.L. (ed.). New York: Academic Press 1973Google Scholar
  136. 136.
    Bjerre-Petersen, E., Christensen, J., Hemmingsen, P.: Industrial gums. Whistler, R.L. (ed.). New York: Academic Press 1973Google Scholar
  137. 137.
    Adams, M.F., Ettling, B.V.: In: Industrial gums. Whistler, R.L. (ed.). New York: Academic Press 1973Google Scholar
  138. 138.
    Towle, G.A., Christensen, O.: In: Industrial gums. Whistler, R.L. (ed.). New York: Academic Press 1973Google Scholar
  139. 139.
    Lowry, J.R.: U.S. Pat. 3,034,973 (1962)Google Scholar
  140. 140.
    Strong, C.H.G.: U.S. Pat. 3,856,596 (1974)Google Scholar

Copyright information

© Springer-Verlag 1980

Authors and Affiliations

  • Gary W. Pace
    • 1
  • Renton C. Righelato
    • 2
  1. 1.BiospecialtiesReadingU.K.
  2. 2.Group Research and Development Philip Lyle Memorial Research LaboratoryTate & Lyle LimitedReadingU.K.

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