Alkyne and Alkene Insertion into Metal–Heteroatom and Metal–Hydrogen Bonds: The Key Stages of Hydrofunctionalization Process

  • Valentine P. AnanikovEmail author
  • Irina P. Beletskaya
Part of the Topics in Organometallic Chemistry book series (TOPORGAN, volume 43)


In this chapter we review mechanistic concepts of carbon–heteroatom bond formation involving hydrofunctionalization of double and triple carbon–carbon bonds via migratory insertion pathway. A variety of useful synthetic procedures were developed within the scope of hydrofunctionalization reaction involving transition metal catalysts to change the direction of the addition reaction and to improve the selectivity of the process. Outstanding potential of multiple bonds activation and insertion in the metal complexes is far from being fully explored. The key factors determining insertion pathways into metal–heteroatom vs. metal–hydrogen bonds and the influence on regioselectivity of the insertion remain to be revealed in nearest future.


Alkenes Alkynes Catalysis Insertion Mechanism Selectivity 


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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  1. 1.Zelinsky Institute of Organic ChemistryRussian Academy of SciencesMoscowRussia
  2. 2.Chemistry DepartmentLomonosov Moscow State UniversityMoscowRussia

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