A multi-scale line filter with automatic scale selection based on the Hessian matrix for medical image segmentation

  • C. Lorenz
  • I. -C. Carlsen
  • T. M. Buzug
  • C. Fassnacht
  • J. Weese
Regular Papers
Part of the Lecture Notes in Computer Science book series (LNCS, volume 1252)


A multi-scale segmentation technique for line-like structures in 2D and 3D medical images is presented. It is based on normalized second derivatives and on the eigenvector analysis of the Hessian matrix. The method allows for the estimation of the local diameter, the longitudinal direction and the contrast of line-structures and for the distinction between edge-like and line-like structures. The characteristics of the method in respect to several analytic line-profiles as well as the influence of neighboring structures and line-bending is discussed. The method is applied to 3D medical images.


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Copyright information

© Springer-Verlag 1997

Authors and Affiliations

  • C. Lorenz
    • 1
  • I. -C. Carlsen
    • 1
  • T. M. Buzug
    • 1
  • C. Fassnacht
    • 1
  • J. Weese
    • 1
  1. 1.Technical Systems DepartmentPhilips ResearchHamburgGermany

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