Multiple alignment with guaranteed error bounds and communication cost

  • Pavel A. Pevzner
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 644)


Multiple sequence alignment is an important problem in computational molecular biology. Dynamic programming for optimal multiple alignment requires too much time to be practical. Although many algorithms for suboptimal alignment have been suggested, no ‘performance guarantees’ algorithms have been known until recently. We give an approximation multiple alignment algorithm with guaranteed error bounds equal to the normalized communication cost of a corresponding graph.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1992

Authors and Affiliations

  • Pavel A. Pevzner
    • 1
  1. 1.Department of MathematicsUniversity of Southern CaliforniaLos Angeles

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