Recurrence Quantification Analysis to Characterise the Heart Rate Variability Before the Onset of Ventricular Tachycardia

  • Niels Wessel
  • Norbert Marwan
  • Udo Meyerfeldt
  • Alexander Schirdewan
  • Jürgen Kurths
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 2199)


Ventricular tachycardia or fibrillation (VT) as fatal cardiac arrhythmias are the main factors triggering sudden cardiac death. The objective of this recurrence quantification analysis approach is to find early signs of sustained VT in patients with an implanted cardioverter-defibrillator (ICD). These devices are able to safeguard patients by returning their hearts to a normal rhythm via strong defibrillatory shocks; additionally, they are able to store at least 1000 beat-to-beat intervals immediately before the onset of a life-threatening arrhythmia. We study these 1000 beat-to-beat intervals of 63 chronic heart failure ICD patients before the onset of a life-threatening arrthymia and at a control time, i.e. without VT event. We find that no linear parameter shows significant differences in heart rate variability between the VT and the control time series. However, the results of the recurrence quantification analysis are promising for this classification task.


Heart Rate Variability Ventricular Tachycardia Implantable Cardioverter Defibrillator Recurrence Plot Heart Rate Variability Parameter 
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  1. 1.
    Mirowski, M., Reid, P.R., Mower, M.M., Watkins, L., Gott, V.L., Schauble, J.F., Langer, A., Heilman, M.S., Kolenik, S.A., Fischell, R.E., Weisfeldt, M.L.: Termination of malignant ventricular tachyarrhythmias with an implanted automatic defibrillator in human beings. N Engl J Med 303 (1980) 322–324CrossRefGoogle Scholar
  2. 2.
    Grimm, W., Floresm, B.T., Marchlinski, F.E.: Shock occurence and survival in 241 patients with implantable cardioverter-defibrillator therapy. Circulation 87 (1993) 18880–18888Google Scholar
  3. 3.
    The antiarrhythmic versus implantable defibrillators (AVID) investigators: A comparison of antiarrhythmic drug therapy with implantable defibrillators in patients resuscitated from near fatal ventricular arrhythmias. N Engl J Med 337 (1997) 1576–1583Google Scholar
  4. 4.
    Hook, B.G., Callans, D.J., Kleiman, R.B., Flores, B.T., Marchlinski, F.E.: Implantable cardioverter-defibrillator therapy in the absence of significant symptoms. Circulation 87 (1993) 1897–1906Google Scholar
  5. 5.
    Gronefeld, G.C., Mauss, O., Li, Y.G., Klingeheben, T., Hohnloser, S.H.: Association between atrial fibrillation and appropriate implantable cardioverted defibrillator therapy: results from a prospective study. J Cardiovasc Electrophysiol 11 (2000) 1208–1214CrossRefGoogle Scholar
  6. 6.
    Kleiger, R.E., Miller, J.P., Bigger, J.T., Moss, A.: Decreased heart rate variability and its association with increased mortality after acute myocardial infarction. Am J Cardiol 59 (1987) 256–262CrossRefGoogle Scholar
  7. 7.
    Tsuji, H., Larson, M.G., Venditti, F.J. Jr, Manders, E.S., Evans, J.C., Feldman, C.L., Levy, D.: Impact of reduced heart rate variability on risk for cardiac events. The Framingham Heart Study. Circulation 94 (1996) 2850–2855Google Scholar
  8. 8.
    Kurths, J., Voss, A., Witt, A., Saparin, P., Kleiner, H.J., Wessel, N.: Quantitative analysis of heart rate variability. Chaos 5 (1995) 88–94CrossRefGoogle Scholar
  9. 9.
    Voss, A., Kurths, J., Kleiner, H.J., Witt, A., Wessel, N., Saparin, P., Osterziel, K.J., Schurath, R., Dietz, R.: The application of methods of non-linear dynamics for the improved and predictive recognition of patients threatened by sudden cardiac death. Cardiovasc Res 31 (1996) 419–433CrossRefGoogle Scholar
  10. 10.
    Wessel, N., Ziehmann, Ch., Kurths, J., Meyerfeldt, U., Schirdewan, A., Voss, A.: Short-term Forecasting of Life-threatening Cardiac Arrhythmias based on Symbolic Dynamics and Finite-Time Growth Rates. Phys Rev E 61 (2000) 733–739CrossRefGoogle Scholar
  11. 11.
    Wessel, N., Voss, A., Malberg, H., Ziehmann, Ch., Voss, H.U., Schirdewan, A., Meyerfeldt, U., Kurths, J.: Nonlinear analysis of complex phenomena in cardiological data. Herzschr Elektrophys 11 (2000) 159–173CrossRefGoogle Scholar
  12. 12.
    Heart rate variability: standards of measurement, physiological interpretation and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electropysiology. Circulation 93 (1996) 1043–1065Google Scholar
  13. 13.
    Eckmann, J.-P., Kamphorst, S.O., Ruelle, D.: Recurrence plots of dynamical systems. Europhys Lett 4 (1987) 973–977CrossRefGoogle Scholar
  14. 14.
    Argyris, J.H., Faust, G., Haase, M.: An exploration of Chaos. North Holland, Amsterdam, 1994zbMATHGoogle Scholar
  15. 15.
    Ott, E.: Chaos in dynamical systems: University Press, Cambridge, 1993zbMATHGoogle Scholar
  16. 16.
    Zbilut, J.P., Webber Jr., C.L.: Embeddings and delays as derived from quantification of recurrence plots. Phys. Lett. A 171 (1992) 199–203CrossRefGoogle Scholar
  17. 17.
    Giuliani, A., Piccirillo, G., Marigliano, V., Colosimo, A.: A nonlinear explanation of aging-induced changes in heartbeat dynamics. Am J Physiol 275 (1998) H1455-H14691Google Scholar
  18. 18.
    Gonzalez, J.J., Cordero, J.J., Feria, M., Pereda, E.: Detection and sources of nonlinearity in the variability of cardiac R-R intervals and blood pressure in rats. Am J Physiol Heart Circ Physiol 279 (2000) H3040-H3046Google Scholar
  19. 19.
    Censi, F., Barbaro, V., Bartolini, P., Calcagnini, G., Michelucci, G. F., Cerutti, S.: Recurrent patterns of atrial depolarization during atrial fibrillation assessed by recurrence plot quantification. in: Annals of Biomedical Engineering 28 (2000), 61–70CrossRefGoogle Scholar
  20. 20.
    Gao, J., Cai, H.: On the structures and quantification of recurrence plots. Physics Letter A 270 (2000), 75–87CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2001

Authors and Affiliations

  • Niels Wessel
    • 1
  • Norbert Marwan
    • 1
  • Udo Meyerfeldt
    • 2
  • Alexander Schirdewan
    • 2
  • Jürgen Kurths
    • 1
  1. 1.University of PotsdamPotsdamGermany
  2. 2.Franz-Volhard-HospitalHumboldt-UniversityBerlinBerlinGermany

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