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Web-Enabled Knowledge-Based Analysis of Genetic Data

  • Peter Juvan
  • Blaž Zupan
  • Janez Demšar
  • Ivan Bratko
  • John A. Halter
  • Adam Kuspa
  • Gad Shaulsky
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 2199)

Abstract

We present a web-based implementation of GenePath, an intelligent assistant tool for data analysis in functional genomics. GenePath considers mutant data and uses expert-defined patterns to find gene-to-gene or gene-to-outcome relations. It presents the results of analysis as genetic networks, wherein a set of genes has various influence on one another and on a biological outcome. In the paper, we particularly focus on its web-based interface and explanation mechanisms.

Keywords

Functional Genomic Genetic Network Mutant Data Network Constraint Abductive Inference 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2001

Authors and Affiliations

  • Peter Juvan
    • 1
  • Blaž Zupan
    • 1
    • 3
  • Janez Demšar
    • 1
  • Ivan Bratko
    • 1
    • 2
  • John A. Halter
    • 4
  • Adam Kuspa
    • 5
    • 6
  • Gad Shaulsky
    • 6
  1. 1.Faculty of Computer and Information ScienceUniversity of LjubljanaSlovenia
  2. 2.Jožef Stefan InstituteLjubljanaSlovenia
  3. 3.Office of Information Technology and Department of Family and Community MedicineBaylor College of MedicineHoustonUSA
  4. 4.Division of NeuroscienceUSA
  5. 5.Department of Biochemistry and Molecular BiologyBaylor College of MedicineHoustonUSA
  6. 6.Department of Molecular and Human GeneticsBaylor College of MedicineHoustonUSA

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