Multiscale Modeling of Alternative Splicing Regulation

  • Damien Eveillard
  • Delphine Ropers
  • Hidde de Jong
  • Christiane Branlant
  • Alexander Bockmayr
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 2602)

Abstract

Alternative plicing is a key process in post-transcriptional regulation, by which several kind of mature RNA can be obtained from the ame premessenger RNA. Using a constraint programming approach, we model the alternative plicing regulation at different scales (single site vs. multiple sites), thus exploiting different types of available experimental data.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2003

Authors and Affiliations

  • Damien Eveillard
    • 1
  • Delphine Ropers
    • 2
  • Hidde de Jong
    • 3
  • Christiane Branlant
    • 2
  • Alexander Bockmayr
    • 1
  1. 1.LORIAUniver itéHenriPoincaréVandæuvre-lès-NancyFrance
  2. 2.Laboratoire de Maturation de ARN et Enzymologie MoléculaireVandœuvre-lès-NancyFrance
  3. 3.INRIA Rhône-Alpe ,Helix ProjectMontbonnotFrance

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