Antibiodic Resistance in the Intensive Care Unit

  • L. del Sorbo
  • J. C. Marshall
Conference paper
Part of the Yearbook of Intensive Care and Emergency Medicine book series (YEARBOOK, volume 2006)

Conclusion

Escalating rates of antimicrobial resistance among Gram-positive and Gram-negative bacteria provide particular challenges for the treatment of critically ill patients.

Widespread empiric antibiotic therapy in the ICU has fostered the emergence and dissemination of resistant bacteria. However, strategies aimed at controlling antibiotic use have been only partially successful. Normal host-microbial interactions are complex, and inappropriate use of antimicrobials can disrupt this fine balance, with deleterious consequences for both host and micro-organism: the line between benefit and harm is a fine one. More rational administration of antimicrobial agents and more reliable and rapid diagnostic technologies, are key priorities for future development.

Keywords

Antibiotic Resistance Antimicrobial Resistance National Nosocomial Infection Surveillance Curr Opin Crit Antibiotic Resistance Factor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Springer-Verlag Berlin Heidelberg 2006

Authors and Affiliations

  • L. del Sorbo
    • 1
  • J. C. Marshall
    • 1
  1. 1.Department of Surgery and Critical Care MedicineUniversity of Toronto St. Michael’s HospitalTorontoCanada

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