Systems-based Analysis of Plant Metabolism by Integration of Metabolomics with Transcriptomics

  • M. Y. Hirai
  • T. Tohge
  • K. Saito
Part of the Biotechnology in Agriculture and Forestry book series (AGRICULTURE, volume 57)

6 Conclusions

In the present studies on sulfur metabolism and anthocyanin production, we could integrate metabolomics and transcriptomics and predict comprehensively gene function especially in secondary metabolism. Concerning the production of secondary metabolites, the regulation at the transcriptional level may be dominant over other regulation at translational and enzymatic activity levels, and hence the transcript profile may determine directly the metabolite profile. We believe that almost all genes involved in the secondary metabolism of interest can be identified by the approach presented in this article. This type of functional genomics can be applied to novel biosynthetic pathway in non-model plants, crops and medicinal plants by using transcriptome analysis such as cDNA-AFLP and cDNA subtraction as substitutions for DNA array.


Anthocyanin Biosynthesis Sulfur Metabolism Anthocyanin Production Sulfur Assimilation Green Star 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2006

Authors and Affiliations

  • M. Y. Hirai
    • 1
  • T. Tohge
    • 1
  • K. Saito
    • 1
    • 2
    • 3
  1. 1.RIKEN Plant Science CenterYokohama, KanagawaJapan
  2. 2.Department of Molecular Biology and Biotechnology, Graduate School of Pharmaceutical SciencesChiba UniversityChibaJapan
  3. 3.Japan Science and Technology AgencyCRESTKawaguchi, SaitamaJapan

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