Coronary Artery Anomalies

  • Andrew M. CreanEmail author
Part of the Medical Radiology book series (MEDRAD)


Coronary anomalies are uncommon yet occur not infrequently in the practice of any regular cardiac imager. They can be among both the most challenging and satisfying of lesions to investigate, and frequently noninvasive imaging represents the standard of reference for full description and understanding of the abnormality in question. This article uses a broad definition of coronary anomalies to include all non-atherosclerotic forms of coronary abnormality—not simply congenital anomalies, but also inflammatory anomalies (e.g., due to Kawasaki or Behcet disease) and postsurgical anomalies (e.g., after Ross, Bentall, or arterial switch procedure).


  1. Al-Turki MA, Patton D, Crean AM, Horlick E, Dhillon R, Johri AM (2015) Spontaneous thrombosis of a left circumflex artery fistula draining into the coronary sinus. World J Pediatr Congenit Heart Surg 6(4):640–642PubMedGoogle Scholar
  2. Angelini P (2014) Novel imaging of coronary artery anomalies to assess their prevalence, the causes of clinical symptoms, and the risk of sudden cardiac death. Circ Cardiovasc Imaging 7(4):747–754PubMedGoogle Scholar
  3. Angelini P, Flamm SD (2007) Newer concepts for imaging anomalous aortic origin of the coronary arteries in adults. Catheter Cardiovasc Interv 69(7):942–954PubMedGoogle Scholar
  4. Angelini P, Uribe C, Monge J, Tobis JM, Elayda MA, Willerson JT (2015) Origin of the right coronary artery from the opposite sinus of Valsalva in adults: characterization by intravascular ultrasonography at baseline and after stent angioplasty. Catheter Cardiovasc Interv 86(2):199–208PubMedPubMedCentralGoogle Scholar
  5. Argo A, Zerbo S, Maresi EG, Rizzo AM, Sortino C, Grassedonio E et al (2016) Utility of post mortem MRI in definition of thrombus in aneurismatic coronary arteries due to incomplete Kawasaki disease in infants. J Forens Radiol Imag 7:17–20Google Scholar
  6. Bajona P, Maselli D, Dore R, Minzioni G (2007) Anomalous origin of the left main artery from the pulmonary artery: adult presentation with systemic collateral supply and giant right coronary artery aneurysm. J Thorac Cardiovasc Surg 134(2):518–520PubMedGoogle Scholar
  7. Baks T, Cademartiri F, Moelker AD, Weustink AC, van Geuns R-J, Mollet NR et al (2006) Multislice computed tomography and magnetic resonance imaging for the assessment of reperfused acute myocardial infarction. J Am Coll Cardiol 48(1):144–152PubMedGoogle Scholar
  8. Bartoloni G, Giorlandino A, Calafiore AM, Caltabiano R, Cosentino S, Algieri G et al (2012) Multiple coronary artery-left ventricular fistulas causing sudden death in a young woman. Hum Pathol 43(9):1520–1523PubMedGoogle Scholar
  9. Basha KMS, Vaijyanath P, Thomas S (2016) Adult type ALCAPA–A rare presentation. J Indian Colleg CardiolGoogle Scholar
  10. Basso C, Maron BJ, Corrado D, Thiene G (2000) Clinical profile of congenital coronary artery anomalies with origin from the wrong aortic sinus leading to sudden death in young competitive athletes. J Am Coll Cardiol 35(6):1493–1501PubMedGoogle Scholar
  11. Bravo-Valenzuela NJM, Silva GRN (2015) Aneurysm of the left coronary artery in postoperative bland-white-garland syndrome. Case Rep Cardiol 2015:568014PubMedPubMedCentralGoogle Scholar
  12. Brothers JA, McBride MG, Seliem MA, Marino BS, Tomlinson RS, Pampaloni MH et al (2007) Evaluation of myocardial ischemia after surgical repair of anomalous aortic origin of a coronary artery in a series of pediatric patients. J Am Coll Cardiol 50(21):2078–2082PubMedGoogle Scholar
  13. Buecker A, Katoh M, Krombach GA, Spuentrup E, Bruners P, Günther RW et al (2005) A feasibility study of contrast enhancement of acute myocardial infarction in multislice computed tomography: comparison with magnetic resonance imaging and gross morphology in pigs. Investig Radiol 40(11):700–704Google Scholar
  14. Burchill L, Huang J, Tretter J, Khan A, Crean A, Veldtman G et al (2017) Noninvasive imaging in adult congenital heart disease. Circ Res 120:995–1014PubMedGoogle Scholar
  15. Burk LM, Wang K-H, Wait JM, Kang E, Willis M, Lu J et al (2015) Delayed contrast enhancement imaging of a murine model for ischemia reperfusion with carbon nanotube micro-CT. PLoS One 10(1):e0115607PubMedPubMedCentralGoogle Scholar
  16. Cheitlin MD, De Castro CM, McAllister HA (1974) Sudden death as a complication of anomalous left coronary origin from the anterior sinus of Valsalva, a not-so-minor congenital anomaly. Circulation 50(4):780–787PubMedGoogle Scholar
  17. Courand P-Y, Bozio A, Ninet J, Henaine R, Veyrier M, Bakloul M et al (2013) Focus on echocardiographic and Doppler analysis of coronary artery abnormal origin from the pulmonary trunk with mild myocardial dysfunction. Echocardiography 30(7):829–836PubMedGoogle Scholar
  18. Crean AM, Kilcullen N, Younger JF (2008) Arrhythmic acute coronary syndrome and anomalous left main stem artery: culprit or innocent bystander. Acute Card Care 10(1):60–61PubMedGoogle Scholar
  19. Crean AM, Spears DA, Suszko AM, Chauhan VS (2013) High-resolution 3D scar imaging using a novel late iodine enhancement multidetector CT protocol to guide ventricular tachycardia catheter ablation. J Cardiovasc Electrophysiol 24(6):708–710PubMedGoogle Scholar
  20. Crean AM, Deva DP, Wald R (2016) Emerging role of stress perfusion cardiovascular magnetic resonance in the patient with congenital heart disease. In: da Cruz EM, Ivy D, Hraska V, Jaggers J (eds) Pediatric and congenital cardiology, cardiac surgery and intensive care. Springer, London, pp 1–22Google Scholar
  21. Deux J-F, Potet J, Lim P, Teiger E, Mayer J, Bensaid A et al (2013) Is multidetector computed tomography a suitable alternative to MR imaging for the assessment of myocardial necrosis after alcohol septal ablation? Int J Cardiol 164(3):306–311PubMedGoogle Scholar
  22. Deva DP, Torres FS, Wald RM, Roche SL, Jimenez-Juan L, Oechslin EN et al (2014) The value of stress perfusion cardiovascular magnetic resonance imaging for patients referred from the adult congenital heart disease clinic: 5-year experience at the Toronto General Hospital. Cardiol Young 24(5):822–830PubMedPubMedCentralGoogle Scholar
  23. Dichtl W, Waldenberger P, Pachinger O, Müller S (2005) An uncommon coronary artery fistula causing survived sudden cardiac death in a young woman. Int J Card Imaging 21(4):387–390Google Scholar
  24. Dwivedi G, Al-Shehri H, deKemp RA, Ali I, Alghamdi AA, Klein R et al (2013) Scar imaging using multislice computed tomography versus metabolic imaging by F-18 FDG positron emission tomography: a pilot study. Int J Cardiol 168(2):739–745PubMedGoogle Scholar
  25. Eid AH, Itani Z, Al-Tannir M, Sayegh S, Samaha A (2009) Primary congenital anomalies of the coronary arteries and relation to atherosclerosis: an angiographic study in Lebanon. J Cardiothorac Surg 4:58PubMedPubMedCentralGoogle Scholar
  26. El-Segaier M, Galal M (2013) Intracoronary thrombus in an infant with Kawasaki disease and giant coronary aneurysm. Acta Paediatr 102(5):e227–e228PubMedGoogle Scholar
  27. Erol C, Seker M (2011) Coronary artery anomalies: the prevalence of origination, course, and termination anomalies of coronary arteries detected by 64-detector computed tomography coronary angiography. J Comput Assist Tomogr 35(5):618–624PubMedGoogle Scholar
  28. Esposito A, Palmisano A, Antunes S, Maccabelli G, Colantoni C, Rancoita PMV et al (2016) Cardiac CT with delayed enhancement in the characterization of ventricular tachycardia structural substrate: relationship between CT-segmented scar and electro-anatomic mapping. JACC Cardiovasc Imaging 9(7):822–832PubMedGoogle Scholar
  29. Fierens C, Budts W, Denef B, Van De Werf F (2000) A 72 year old woman with ALCAPA. Heart 83(1):E2PubMedPubMedCentralGoogle Scholar
  30. Frapier JM, Leclercq F, Bodino M, Chaptal PA (1999) Malignant ventricular arrhythmias revealing anomalous origin of the left coronary artery from the pulmonary artery in two adults. Eur J Cardiothorac Surg 15(4):539–541PubMedGoogle Scholar
  31. Fujimoto S, Kondo T, Orihara T, Sugiyama J, Kondo M, Kodama T et al (2011) Prevalence of anomalous origin of coronary artery detected by multi-detector computed tomography at one center. J Cardiol 57(1):69–76PubMedGoogle Scholar
  32. Garg N, Tewari S, Kapoor A, Gupta DK, Sinha N (2000) Primary congenital anomalies of the coronary arteries: a coronary: arteriographic study. Int J Cardiol 74(1):39–46PubMedGoogle Scholar
  33. Ghaderi F, Gholoobi A, Moeinipour A (2014) Unique echocardiographic markers of anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) in the adult. Echocardiography 31(1):E13–E15PubMedGoogle Scholar
  34. Ghosh A, Agarwala BN (2011) Kawasaki disease: giant aneurysm with a large thrombus of the left coronary artery. Clin Pract 1(2):e23PubMedPubMedCentralGoogle Scholar
  35. Gillebert C, Van Hoof R, Van de Werf F, Piessens J, De Geest H (1986) Coronary artery fistulas in an adult population. Eur Heart J 7(5):437–443PubMedGoogle Scholar
  36. Graidis C, Dimitriadis D, Karasavvidis V, Dimitriadis G, Argyropoulou E, Economou F et al (2015) Prevalence and characteristics of coronary artery anomalies in an adult population undergoing multidetector-row computed tomography for the evaluation of coronary artery disease. BMC Cardiovasc Disord 15:112PubMedPubMedCentralGoogle Scholar
  37. Gräni C, Buechel RR, Kaufmann PA, Kwong RY (2017) Multimodality imaging in individuals with anomalous coronary arteries. JACC Cardiovasc Imaging 10(4):471–481PubMedGoogle Scholar
  38. Greenwood JP, Maredia N, Younger JF, Brown JM, Nixon J, Everett CC et al (2012) Cardiovascular magnetic resonance and single-photon emission computed tomography for diagnosis of coronary heart disease (CE-MARC): a prospective trial. Lancet 379(9814):453–460PubMedPubMedCentralGoogle Scholar
  39. Greenwood JP, Herzog BA, Brown JM, Everett CC, Nixon J, Bijsterveld P et al (2016) Prognostic value of cardiovascular magnetic resonance and single-photon emission computed tomography in suspected coronary heart disease: long-term follow-up of a prospective, diagnostic accuracy cohort study. Ann Intern Med 165(1):1–9Google Scholar
  40. Habis M, Capderou A, Sigal-Cinqualbre A, Ghostine S, Rahal S, Riou JY et al (2009) Comparison of delayed enhancement patterns on multislice computed tomography immediately after coronary angiography and cardiac magnetic resonance imaging in acute myocardial infarction. Heart 95(8):624–629PubMedGoogle Scholar
  41. Harada M, Akimoto K, Ogawa S, Kato H, Nakamura Y, Hamaoka K et al (2013) National Japanese survey of thrombolytic therapy selection for coronary aneurysm: intracoronary thrombolysis or intravenous coronary thrombolysis in patients with Kawasaki disease. Pediatr Int 55(6):690–695PubMedGoogle Scholar
  42. Hofmeyr L, Moolman J, Brice E, Weich H (2009) An unusual presentation of an anomalous left coronary artery arising from the pulmonary artery (ALCAPA) in an adult: anterior papillary muscle rupture causing severe mitral regurgitation. Echocardiography 26(4):474–477PubMedGoogle Scholar
  43. Hundley WG, Li HF, Lange RA, Pfeifer DP, Meshack BM, Willard JE et al (1995) Assessment of left-to-right intracardiac shunting by velocity-encoded, phase-difference magnetic resonance imaging. A comparison with oximetric and indicator dilution techniques. Circulation 91(12):2955–2960PubMedGoogle Scholar
  44. Jacquier A, Revel D, Saeed M (2008) MDCT of the myocardium: a new contribution to ischemic heart disease. Acad Radiol 15(4):477–487PubMedGoogle Scholar
  45. Jin YD, Hsiung MC, Tsai SK, Chang C-Y, Wei J, Ou C et al (2011) Successful intraoperative identification of an anomalous origin of the left coronary artery from the pulmonary artery using real time three-dimensional transesophageal echocardiography. Echocardiography 28(7):E149–E151PubMedGoogle Scholar
  46. Kang WC, Chung W-J, Choi CH, Park KY, Jeong MJ, Ahn TH et al (2007) A rare case of anomalous left coronary artery from the pulmonary artery (ALCAPA) presenting congestive heart failure in an adult. Int J Cardiol 115(2):e63–e67PubMedGoogle Scholar
  47. Keir M, Wald RM, Roche SL, Oechslin EN, Horlick E, Osten MD et al (2015) Does a dedicated subspecialty ACHD coronary clinic result in greater consistency in approach and reduced loss to follow-up? An evaluation of the first 3years of the Toronto congenital coronary Clinic for Adults. Prog Pediatr Cardiol 39(2):145–150Google Scholar
  48. Keir M, Spears D, Caldarone C, Crean AM (2017) Proving the innocence of a “malignant” coronary artery: calling dobutamine stress CT for the defence. J Cardiovasc Comput Tomogr 11(1):68–69PubMedGoogle Scholar
  49. Kragel AH, Roberts WC (1988) Anomalous origin of either the right or left main coronary artery from the aorta with subsequent coursing between aorta and pulmonary trunk: analysis of 32 necropsy cases. Am J Cardiol 62(10 Pt 1):771–777PubMedGoogle Scholar
  50. Kramer PH, Goldstein JA, Herkens RJ, Lipton MJ, Brundage BH (1984) Imaging of acute myocardial infarction in man with contrast-enhanced computed transmission tomography. Am Heart J 108(6):1514–1523PubMedGoogle Scholar
  51. Krexi L, Sheppard MN (2013) Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA), a forgotten congenital cause of sudden death in the adult. Cardiovasc Pathol 22(4):294–297PubMedGoogle Scholar
  52. Kristensen T, Kofoed KF, Helqvist S, Helvind M, Søndergaard L (2008) Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) presenting with ventricular fibrillation in an adult: a case report. J Cardiothorac Surg 3:33PubMedPubMedCentralGoogle Scholar
  53. Kuramochi Y, Ohkubo T, Takechi N, Fukumi D, Uchikoba Y, Ogawa S (2000) Hemodynamic factors of thrombus formation in coronary aneurysms associated with Kawasaki disease. Pediatr Int 42(5):470–475PubMedGoogle Scholar
  54. Lardo AC, Cordeiro MAS, Silva C, Amado LC, George RT, Saliaris AP et al (2006) Contrast-enhanced multidetector computed tomography viability imaging after myocardial infarction: characterization of myocyte death, microvascular obstruction, and chronic scar. Circulation 113(3):394–404PubMedPubMedCentralGoogle Scholar
  55. Lau G (1995) Sudden death arising from a congenital coronary artery fistula. Forensic Sci Int 73(2):125–130PubMedGoogle Scholar
  56. Lee M-L, Chen M (2009) Diagnosis and management of congenital coronary arteriovenous fistula in the pediatric patients presenting congestive heart failure and myocardial ischemia. Yonsei Med J 50(1):95–104PubMedPubMedCentralGoogle Scholar
  57. Lee SE, CW Y, Park K, Park KW, Suh J-W, Cho Y-S et al (2016) Physiological and clinical relevance of anomalous right coronary artery originating from left sinus of Valsalva in adults. Heart 102(2):114–119PubMedGoogle Scholar
  58. Liu Y, Miller BW (2012) ALCAPA presents in an adult with exercise intolerance but preserved cardiac function. Case Rep Cardiol 2012:471759PubMedPubMedCentralGoogle Scholar
  59. Lopes R, Almeida PB, Amorim MJ, Magalhães D, Silva JC, Pinho P et al (2011 Aug) Anomalous origin of the left coronary artery from the pulmonary artery in an asymptomatic adult. Congenit Heart Dis 6(4):366–369PubMedGoogle Scholar
  60. Lowe GDO (2003) Virchow’s triad revisited: abnormal flow. Pathophysiol Haemost Thromb 33(5–6):455–457PubMedGoogle Scholar
  61. Lozano I, Batalla A, Rubin J, Avanzas P, Martin M, Moris C (2008) Sudden death in a patient with multiple left anterior descending coronary artery fistulas to the left ventricle. Int J Cardiol 125(3):e37–e39PubMedGoogle Scholar
  62. de Meester de Ravenstein C, Bouzin C, Lazam S, Boulif J, Amzulescu M, Melchior J et al (2015) Histological validation of measurement of diffuse interstitial myocardial fibrosis by myocardial extravascular volume fraction from modified look-locker imaging (MOLLI) T1 mapping at 3 T. J Cardiovasc Magn Reson 17:48Google Scholar
  63. Mendiola Ramírez K, Osorio Díaz JO, Maldonado Velázquez Mdel R, Faugier Fuentes E (2011) Kawasaki’s disease in remission with cardiac involvement: intrasacular thrombus in a giant aneurism of both coronary arteries. Case report. Reumatol Clin 7(5):329–332PubMedGoogle Scholar
  64. Nakahira A, Sasaki Y, Hirai H, Fukui T, Motoki M, Takahashi Y et al (2007) Rupture of aneurysmal circumflex coronary artery into the left atrium after ligation of its arteriovenous fistula. Circ J 71(12):1996–1998PubMedGoogle Scholar
  65. Namgung J, Kim JA (2014) The prevalence of coronary anomalies in a single center of Korea: origination, course, and termination anomalies of aberrant coronary arteries detected by ECG-gated cardiac MDCT. BMC Cardiovasc Disord 14:48PubMedPubMedCentralGoogle Scholar
  66. Nony P, Beaune J, Champsaur G, Bozio A, Age C, Fontana J et al (1992) Anomalous origin of left coronary artery from the pulmonary artery: evolution of left ventricular function and perfusion after surgery in a 44-year-old man. Clin Cardiol 15(6):466–468PubMedGoogle Scholar
  67. Okura N, Okuda T, Shiotani S, Kohno M, Hayakawa H, Suzuki A et al (2013) Sudden death as a late sequel of Kawasaki disease: postmortem CT demonstration of coronary artery aneurysm. Forensic Sci Int 225(1–3):85–88PubMedGoogle Scholar
  68. Pachon R, Bravo C, Niemiera M (2015) Sudden cardiac death as a presentation of anomalous origin of the left coronary artery from pulmonary artery in a young adult. Eur Heart J Acute Cardiovasc Care 4(6):589–590PubMedGoogle Scholar
  69. Patil S, Shirodkar S, Pinto R, Dalvi B (2008) Giant coronary artery aneurysm with a thrombus secondary to Kawasaki disease. Ann Pediatr Cardiol 1(1):59–61PubMedPubMedCentralGoogle Scholar
  70. Peña E, Nguyen ET, Merchant N, Dennie C (2009) ALCAPA syndrome: not just a pediatric disease. Radiographics 29(2):553–565PubMedGoogle Scholar
  71. Quah JX, Hofmeyr L, Haqqani H, Clarke A, Rahman A, Pohlner P et al (2014) The management of the older adult patient with anomalous left coronary artery from the pulmonary artery syndrome: a presentation of two cases and review of the literature. Congenit Heart Dis 9(6):E185–E194PubMedGoogle Scholar
  72. Raghuram AR, Krishnan R, Kumar S, Balamurugan K, Anand ND (2004) Anomalous left coronary artery from pulmonary artery (ALCAPA) in an adult. Indian J Thorac Cardiovasc Surg 20(4):213–215Google Scholar
  73. Rajs J, Brodin LA, Hertzfeld I, Larsen FF (2001) Death related to coronary artery fistula after rupture of an aneurysm to the coronary sinus. Am J Forensic Med Pathol 22(1):58–61PubMedGoogle Scholar
  74. Rana O, Swallow R, Senior R, Greaves K (2009) Detection of myocardial ischaemia caused by coronary artery-left ventricular fistulae using myocardial contrast echocardiography. Eur J Echocardiogr 10(1):175–177PubMedGoogle Scholar
  75. Ripley DP, Gosling OE, Harries S, Spurrell PA, Bellenger NG (2014) Multimodality imaging in bland-White-Garland syndrome in an adult with a left dominant coronary artery system. Congenit Heart Dis 9(4):E110–E112PubMedGoogle Scholar
  76. Rizk SRY, El Said G, Daniels LB, Burns JC, El Said H, Sorour KA et al (2015) Acute myocardial ischemia in adults secondary to missed Kawasaki disease in childhood. Am J Cardiol 115(4):423–427PubMedGoogle Scholar
  77. Roberts WC, Siegel RJ, Zipes DP (1982) Origin of the right coronary artery from the left sinus of valsalva and its functional consequences: analysis of 10 necropsy patients. Am J Cardiol 49(4):863–868PubMedGoogle Scholar
  78. Sadanandan R, Thankappan A, Jacob B, Kuriakose KM (2012) Anomalous left coronary artery from pulmonary artery (ALCAPA) repair and mitral valve replacement with bioprosthetic valve with in a 62 year old lady. Indian J Thorac Cardiovasc Surg 28(2):146–147Google Scholar
  79. Safaa AM, LL D, Batra R, Essack N (2013) A rare case of adult type ALCAPA syndrome: presentation, diagnosis and management. Heart Lung Circ 22(6):444–446PubMedGoogle Scholar
  80. Said SA (2016) Characteristics of congenital coronary artery fistulas complicated with infective endocarditis: analysis of 25 reported cases. Congenit Heart Dis 11(6):756–765PubMedGoogle Scholar
  81. Said SAM, Schroeder-Tanka JM, Mulder BJM (2008) Female gender and the risk of rupture of congenital aneurysmal fistula in adults. Congenit Heart Dis 3(1):63–68PubMedGoogle Scholar
  82. Sajjadieh Khajouei A, Samie-Nasab M, Behjati M, Biederman RW (2016) Cardiac computed tomography of an asymptomatic 48-year-old woman with ALCAPA syndrome. Echocardiography 33(12):1923–1925PubMedGoogle Scholar
  83. Secinaro A, Ntsinjana H, Tann O, Schuler PK, Muthurangu V, Hughes M et al (2011) Cardiovascular magnetic resonance findings in repaired anomalous left coronary artery to pulmonary artery connection (ALCAPA). J Cardiovasc Magn Reson 13:27PubMedPubMedCentralGoogle Scholar
  84. Seguchi M, Nakanishi T, Nakazawa M, Doi S, Momma K, Takao A et al (1990) Myocardial perfusion after aortic implantation for anomalous origin of the left coronary artery from the pulmonary artery. Eur Heart J 11(3):213–218PubMedGoogle Scholar
  85. Shabestari AA, Akhlaghpoor S, Tayebivaljozi R, Fattahi Masrour F (2012) Prevalence of congenital coronary artery anomalies and variants in 2697 consecutive patients using 64-detector row coronary CT angiography. Iran J Radiol 9(3):111–121PubMedPubMedCentralGoogle Scholar
  86. Sharples L, Hughes V, Crean A, Dyer M, Buxton M, Goldsmith K et al (2007) Cost-effectiveness of functional cardiac testing in the diagnosis and management of coronary artery disease: a randomised controlled trial. The CECaT Trial Health Technol Assess 11(49):iii–iiv, ixPubMedGoogle Scholar
  87. Shen Q, Yao Q, Hu X (2016) Anomalous origin of the left coronary artery from the pulmonary artery in children: diagnostic use of multidetector computed tomography. Pediatr Radiol 46(10):1392–1398PubMedGoogle Scholar
  88. Silverman NH (2015) Echocardiographic presentation of anomalous origin of the left coronary artery from the pulmonary artery. Cardiol Young 25(8):1512–1523PubMedGoogle Scholar
  89. Sivri N, Aktoz M, Yalta K, Ozcelik F, Altun AA (2012) Retrospective study of angiographic ally determined anomalous coronary arteries in 12,844 subjects in Thrace region of Turkey. Hippokratia 16(3):246–249PubMedPubMedCentralGoogle Scholar
  90. Sohrabi B, Habibzadeh A, Abbasov E (2012) The incidence and pattern of coronary artery anomalies in the north-west of iran: a coronary arteriographic study. Korean Circ J 42(11):753–760PubMedPubMedCentralGoogle Scholar
  91. Song G, Ren W, Liu Z, Wu D (2015) Incomplete Kawasaki disease with coronary artery aneurysm and coronary sinus thrombus. Pediatr Cardiol 36(5):1097–1099PubMedGoogle Scholar
  92. Su C-S, Tsai I-C, Lin W-W, Lin F-Y, Ting C-T, Wang K-Y (2010) Usefulness of multidetector-row computed tomography in diagnosis of anomalous origin of left coronary artery arising from the pulmonary artery. J Chin Med Assoc 73(9):492–495PubMedGoogle Scholar
  93. Teo CHY, Paul G (2005) An uncommon cause of death in an older child part 1. Pathology 37(2):172–173PubMedGoogle Scholar
  94. Thom H, West NEJ, Hughes V, Dyer M, Buxton M, Sharples LD et al (2014) Cost-effectiveness of initial stress cardiovascular MR, stress SPECT or stress echocardiography as a gate-keeper test, compared with upfront invasive coronary angiography in the investigation and management of patients with stable chest pain: mid-term outcomes from the CECaT randomised controlled trial. BMJ Open 4(2):e003419PubMedPubMedCentralGoogle Scholar
  95. Thompson WR (2015) Stress echocardiography in paediatrics: implications for the evaluation of anomalous aortic origin of the coronary arteries. Cardiol Young 25(8):1524–1530PubMedGoogle Scholar
  96. Tobler D, Motwani M, Wald RM, Roche SL, Verocai F, Iwanochko RM et al (2014) Evaluation of a comprehensive cardiovascular magnetic resonance protocol in young adults late after the arterial switch operation for d-transposition of the great arteries. J Cardiovasc Magn Reson 16:98PubMedPubMedCentralGoogle Scholar
  97. Tongut A, Özyedek Z, Çerezci İ, Erentürk S, Hatemi AC (2016) Prevalence of congenital coronary artery anomalies as shown by multi-slice computed tomography coronary angiography: a single-centre study from Turkey. J Int Med Res 44(6):1492–1505PubMedPubMedCentralGoogle Scholar
  98. Toumpourleka M, Belitsis G, Alonso R, Rubens M, Moat N, Gatzoulis M (2015) Late presentation and surgical repair of ALCAPA. Int J Cardiol 186:207–209PubMedGoogle Scholar
  99. Wagner A, Mahrholdt H, Holly TA, Elliott MD, Regenfus M, Parker M et al (2003) Contrast-enhanced MRI and routine single photon emission computed tomography (SPECT) perfusion imaging for detection of subendocardial myocardial infarcts: an imaging study. Lancet 361(9355):374–379PubMedGoogle Scholar
  100. Xu H, Zhu Y, Zhu X, Tang L, Xu Y (2012) Anomalous coronary arteries: depiction at dual-source computed tomographic coronary angiography. J Thorac Cardiovasc Surg 143(6):1286–1291PubMedGoogle Scholar
  101. Yamanaka O, Hobbs RE (1990) Coronary artery anomalies in 126,595 patients undergoing coronary arteriography. Catheter Cardiovasc Diagn 21(1):28–40Google Scholar
  102. Yang Y-L, Nanda NC, Wang X-F, Xie M-X, Lu Q, He L et al (2007) Echocardiographic diagnosis of anomalous origin of the left coronary artery from the pulmonary artery. Echocardiography 24(4):405–411PubMedGoogle Scholar
  103. Yildiz A, Okcun B, Peker T, Arslan C, Olcay A, Bulent Vatan M (2010) Prevalence of coronary artery anomalies in 12,457 adult patients who underwent coronary angiography. Clin Cardiol 33(12):E60–E64PubMedGoogle Scholar
  104. Yuksel S, Meric M, Soylu K, Gulel O, Zengin H, Demircan S et al (2013) The primary anomalies of coronary artery origin and course: a coronary angiographic analysis of 16,573 patients. Exp Clin Cardiol 18(2):121–123PubMedPubMedCentralGoogle Scholar

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© Springer International Publishing AG 2018

Authors and Affiliations

  1. 1.Sanghvi Endowed Chair in Cardiovascular Imaging Professor of Cardiology and PediatricsUniversity of Cincinnati Medical Center and Cincinnati Children’s Hospital Medical CenterCincinnatiUSA

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