Carcinoma of the Vagina

  • Higinia R. Cardenes
  • Jennifer E. Zook
  • David L. Andolino
Part of the Medical Radiology book series (MEDRAD)


Primary vaginal cancer is a rare entity representing about 2% of all female genital neoplasias and only 0.1–0.2% of all cancers (Jemal et al. 59(4):225–249, 2009). Most carcinomas found in the vagina represent direct extension or metastasis from other primary gynecologic (cervix or vulva) and non-gynecologic sites, most commonly breast and gastrointestinal tract. There are a number of controversies in terms of epidemiology, staging, and diagnostic evaluation as well as in the management of vaginal cancer. Because of its rarity, there is a lack of prospective, randomized studies in patients with vaginal cancer, and therefore it is difficult to establish strong, evidence based-recommendations. Decisions regarding therapeutic options are for the most part, based on retrospective data and individual assessment using general principles derived from clinical experience in the cancer management in other sites. Most of the available data refer to the treatment of primary invasive SCC of the vagina, since this represents the most common histology.


Intensity Modulate Radiation Therapy Stereotactic Body Radiotherapy Figo Stage High Dose Rate National Cancer Data Base 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2011

Authors and Affiliations

  • Higinia R. Cardenes
    • 1
  • Jennifer E. Zook
    • 1
  • David L. Andolino
    • 1
  1. 1.Department of Radiation OncologyIndiana University School of MedicineIndianapolisUSA

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