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Advanced Musculoskeletal Magnetic Resonance Imaging at Ultra-high Field (7 T)

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High-Field MR Imaging

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

Abstract

The major advantage of high-field and ultra-high field MR is the shift from morphological to biochemical and metabolic imaging techniques which normally suffer from low sensitivity at standard field strength (1.5 T). The high signal-to-noise ratio of the higher field systems provides biochemical and metabolic imaging in reasonable scan times, which promotes their widespread clinical application. This development enables the diagnosis of diseases such as osteoarthritis, degenerative disc disease, and muscle disease at their earliest stages, before morphological changes occur. Thus, the imaging pre-requisites are available for the evaluation and follow-up of new disease-modifying drugs and the trend toward more personalized medicine.

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Abbreviations

MR:

Magnetic resonance

SNR:

Signal-to-noise ratio

SAR:

Specific absorption rate

TSE:

Turbo Spin Echo

HASTE:

Half-Fourier acquisition single-shot turbo spin echo

TrueFISP:

True Fast Imaging with Steady-state Free Precession

RF:

Radiofrequency

MRI:

Magnetic resonance imaging

μMRI:

Microscopy magnetic resonance imaging

OA:

Osteoarthiritis

UTE:

Ultrashort echo time

NYUMC:

New York University Langone Medical Center

TFCC:

Triangular fibrocartilage complex

PG:

Proteoglycan

GAG:

Glycosaminoglycans

FCD:

Fixed charge density

TQF:

Triple-quantum filtered

TPI:

Twisted projection imaging

SQ:

Single-quantum

dGEMRIC:

Delayed gadolinium enhanced MRI of cartilage

MACT:

Matrix-associated autologous transplantation

3D GRE:

Three dimensional gradient echo

IR:

Inversion recovery

IVD:

Intervertebral discs

AF:

Annulus fibrosus

NP:

Nucleus pulposus

B0:

Main magnetic field

TR:

Repetition time

SE T2 :

Spin-echo T2 relaxation time constant

31P-MRS:

Phosporus MR spectroscopy

1H-MRS:

Hydrogen MR spectroscopy

CSA:

Chemical shift anisotropy

ATP:

Adenosine triphosphate

PME:

Phosphomonoesters

PDE:

Phosphodiester

CSDE:

Chemical shift displacement error

3D-CSI:

Three dimensional Chemical Shift Imaging

PCr:

Phosphocreatine

ADP:

Adenosine diphosphate

PC:

Phosphocholine

PE:

Phosphoethanolamine

Pi:

Inorganic phosphate

GPC:

Glycophosphocholine

Spsp:

Spectral-spatial

FATSAT:

Fat saturation

MTC:

Magnetization transfer contrast

CW:

Continuous wave

SSFP:

Steady-state free precession

DESS:

Double-echo steady state

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Authors and Affiliations

  1. Department of Radiology, High-Field MR Imaging Centre, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria

    Siegfried Trattnig, Klaus Friedrich, Wolfgang Bogner & Goetz H. Welsch

  2. Division of Radiological Physics, Department of Medical Radiology, University of Basel Hospital, Petersgraben 4, 4031, Basel, Switzerland

    Klaus Scheffler & Oliver Bieri

  3. Department of Trauma Surgery, University Hospital of Erlangen, Krankenhaustrasse 12, 91054, Erlangen, Germany

    Goetz H. Welsch

Authors
  1. Siegfried Trattnig
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  2. Klaus Friedrich
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  3. Wolfgang Bogner
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  4. Klaus Scheffler
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  5. Oliver Bieri
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  6. Goetz H. Welsch
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Correspondence to Siegfried Trattnig .

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Editors and Affiliations

  1. Radiologische Klinik, Abt. Chir./Kernspintomographie, Univ.Klinikum Freiburg, Hugstetter Str. 55, Freiburg, 79106, Germany

    Jürgen Hennig

  2. Inst. Experimentelle Physik, Abt. Biomedizinische Magnetresonanz, Otto-von-Guericke Univ. Magdeburg, Leipziger Str. 44, Magdeburg, 39120, Germany

    Oliver Speck

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Trattnig, S., Friedrich, K., Bogner, W., Scheffler, K., Bieri, O., Welsch, G.H. (2012). Advanced Musculoskeletal Magnetic Resonance Imaging at Ultra-high Field (7 T). In: Hennig, J., Speck, O. (eds) High-Field MR Imaging. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2010_99

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  • DOI: https://doi.org/10.1007/174_2010_99

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