Post-polymerization Modification of Surface-Bound Polymers

  • Hanju Jo
  • Patrick Theato
Part of the Advances in Polymer Science book series (POLYMER, volume 270)


Surfaces that have been intricately functionalized with reactive polymers have attracted scientific attention recently because of their potential use in a broad range of applications. Polymers containing chemically reactive functional groups can be utilized for subsequent modification of various surfaces. Reactive polymeric surfaces can be produced by surface-initiated polymerization, such as atom transfer radical polymerization, nitroxide-mediated polymerization, and ring-opening metathesis polymerization. Such surfaces can subsequently undergo post-polymerization modification to alter their physicochemical properties. Post-polymerization modification has a number of advantages, including the fact that diverse polymer structures are rapidly accessible without individual synthesis; polymerization of new functional monomers can produce a variety of surfaces and interfaces; and other materials can be easily modified, which would be difficult using conventional direct polymerization. In addition, the libraries of chemical reactions and materials that can be used in post-polymerization modifications are abundant. Therefore, post-polymerization modification opens up new platforms for the facile and versatile modification of various surfaces. This chapter focuses on a discussion of post-polymerization modification of various surface-bound polymers, from planar surfaces to three-dimensional objects, and on the extended applications of the reactive surfaces.


Click chemistry Functionalized surfaces Multifunctionalization Post-polymerization modification Surface-initiated polymerization 


  1. 1.
    Azzaroni O (2012) Polymer brushes here, there, and everywhere: recent advances in their practical applications and emerging opportunities in multiple research fields. J Polym Sci A Polym Chem 50:3225–3258Google Scholar
  2. 2.
    Tsujii Y, Ohno K, Yamamoto S, Goto A, Fukuda T (2006) Structure and properties of high-density polymer brushes prepared by surface-initiated living radical polymerization. Adv Polym Sci 197:1–45Google Scholar
  3. 3.
    Olivier A, Meyer F, Raquez JM, Damman P, Dubois P (2012) Surface-initiated controlled polymerization as a convenient method for designing functional polymer brushes: from self-assembled monolayers to patterned surfaces. Prog Polym Sci 37:157–181Google Scholar
  4. 4.
    Barbey R, Lavanant L, Paripovic D, Schuwer N, Sugnaux C, Tugulu S, Klok HA (2009) Polymer brushes via surface-initiated controlled radical polymerization: synthesis, characterization, properties, and applications. Chem Rev 109:5437–5527Google Scholar
  5. 5.
    Chen K, Liang D, Tian J, Shi L, Zhao H (2008) In-situ polymerization at the interfaces of micelles: a “grafting from” method to prepare micelles with mixed coronal chains. J Phys Chem B 112:12612–12617Google Scholar
  6. 6.
    Liu X, Guo S, Mirkin CA (2003) Surface and site-specific ring-opening metathesis polymerization initiated by dip-pen nanolithography. Angew Chem Int Ed Engl 42:4785–4789Google Scholar
  7. 7.
    Senkovskyy V, Khanduyeva N, Komber H, Oertel U, Stamm M, Kuckling D, Kiriy A (2007) Conductive polymer brushes of regioregular head-to-tail poly(3-alkylthiophenes) via catalyst-transfer surface-initiated polycondensation. J Am Chem Soc 129:6626–6632Google Scholar
  8. 8.
    Sontag SK, Marshall N, Locklin J (2009) Formation of conjugated polymer brushes by surface-initiated catalyst-transfer polycondensation. Chem Commun 2009(23):3354–3356. doi: 10.1039/B907264KGoogle Scholar
  9. 9.
    Tomlinson MR, Genzer J (2003) Formation of surface-grafted copolymer brushes with continuous composition gradients. Chem Commun 2003(12):1350–1351 doi: 10.1039/B303823HGoogle Scholar
  10. 10.
    Wang X, Tu H, Braun PV, Bohn PW (2006) Length scale heterogeneity in lateral gradients of poly(N-isopropylacrylamide) polymer brushes prepared by surface-initiated atom transfer radical polymerization coupled with in-plane electrochemical potential gradients. Langmuir 22:817–823Google Scholar
  11. 11.
    Zhao B (2004) A combinatorial approach to study solvent-induced self-assembly of mixed poly(methyl methacrylate)/polystyrene brushes on planar silica substrates: effect of relative grafting density. Langmuir 20:11748–11755Google Scholar
  12. 12.
    Edmondson S, Osborne VL, Huck WT (2004) Polymer brushes via surface-initiated polymerizations. Chem Soc Rev 33:14–22Google Scholar
  13. 13.
    Gauthier MA, Gibson MI, Klok HA (2009) Synthesis of functional polymers by post-polymerization modification. Angew Chem Int Ed Engl 48:48–58Google Scholar
  14. 14.
    Boaen NK, Hillmyer MA (2005) Post-polymerization functionalization of polyolefins. Chem Soc Rev 34:267–275Google Scholar
  15. 15.
    Theato P (2008) Synthesis of well-defined polymeric activated esters. J Polym Sci A Polym Chem 46:6677–6687Google Scholar
  16. 16.
    Evans RA (2007) The rise of azide-alkyne 1,3-dipolar ‘click’ cycloaddition and its application to polymer science and surface modification. Aust J Chem 60:384–395Google Scholar
  17. 17.
    Arnold RM, Patton DL, Popik VV, Locklin J (2014) A dynamic duo: pairing click chemistry and postpolymerization modification to design complex surfaces. Acc Chem Res 47:2999–3008Google Scholar
  18. 18.
    Theato P, Klok H-A (2013) Functional polymers by post-polymerization modification : concepts, guidelines, and applications. Wiley-VCH, WeinheimGoogle Scholar
  19. 19.
    Milner ST (1991) Polymer brushes. Science 251:905–914Google Scholar
  20. 20.
    Ionov L, Zdyrko B, Sidorenko A, Minko S, Klep V, Luzinov I, Stamm M (2004) Gradient polymer layers by “grafting to” approach. Macromol Rapid Commun 25:360–365Google Scholar
  21. 21.
    Minko S, Patil S, Datsyuk V, Simon F, Eichhorn KJ, Motornov M, Usov D, Tokarev I, Stamm M (2002) Synthesis of adaptive polymer brushes via “grafting to” approach from melt. Langmuir 18:289–296Google Scholar
  22. 22.
    Advincula RC (2004) Polymer brushes: synthesis, characterization, applications. Wiley-VCH, WeinheimGoogle Scholar
  23. 23.
    Zhao B, Brittain WJ (2000) Polymer brushes: surface-immobilized macromolecules. Prog Polym Sci 25:677–710Google Scholar
  24. 24.
    Brittain WJ, Minko S (2007) A structural definition of polymer brushes. J Polym Sci A Polym Chem 45:3505–3512Google Scholar
  25. 25.
    Iwakura Y, Kurosaki T, Nakabayashi N (1961) Reactive fiber.1. Copolymerization and copolymer of acrylonitrile with glycidyl methacrylate and with glycidyl acrylate. Macromol Chem 44–6:570–590Google Scholar
  26. 26.
    Wong LJ, Sevimli S, Zareie HM, Davis TP, Bulmus V (2010) PEGylated functional nanoparticles from a reactive homopolymer scaffold modified by thiol addition chemistry. Macromolecules 43:5365–5375Google Scholar
  27. 27.
    Henry SM, El-Sayed MEH, Pirie CM, Hoffman AS, Stayton PS (2006) pH-responsive poly(styrene-alt-maleic anhydride) alkylamide copolymers for intracellular drug delivery. Biomacromolecules 7:2407–2414Google Scholar
  28. 28.
    Mansfeld U, Pietsch C, Hoogenboom R, Becer CR, Schubert US (2010) Clickable initiators, monomers and polymers in controlled radical polymerizations – a prospective combination in polymer science. Polym Chem 1:1560–1598Google Scholar
  29. 29.
    Heilmann SM, Rasmussen JK, Krepski LR (2001) Chemistry and technology of 2-alkenyl azlactones. J Polym Sci A Polym Chem 39:3655–3677Google Scholar
  30. 30.
    Kolb HC, Finn MG, Sharpless KB (2001) Click chemistry: diverse chemical function from a few good reactions. Angew Chem Int Ed 40:2004–2021Google Scholar
  31. 31.
    Barner-Kowollik C, Du Prez FE, Espeel P, Hawker CJ, Junkers T, Schlaad H, Van Camp W (2011) “Clicking” polymers or just efficient linking: what is the difference? Angew Chem Int Ed 50:60–62Google Scholar
  32. 32.
    Yang SK, Weck M (2009) Covalent and orthogonal multi-functionalization of terpolymers. Soft Matter 5:582–585Google Scholar
  33. 33.
    Xu JW, Prifti F, Song J (2011) A versatile monomer for preparing well-defined functional polycarbonates and poly(ester-carbonates). Macromolecules 44:2660–2667Google Scholar
  34. 34.
    Pyun J, Kowalewski T, Matyjaszewski K (2003) Synthesis of polymer brushes using atom transfer radical polymerization. Macromol Rapid Commun 24:1043–1059Google Scholar
  35. 35.
    Wu T, Gong P, Szleifer I, Vlcek P, Subr V, Genzer J (2007) Behavior of surface-anchored poly(acrylic acid) brushes with grafting density gradients on solid substrates: 1. Experiment. Macromolecules 40:8756–8764Google Scholar
  36. 36.
    Edmondson S, Huck WTS (2004) Controlled growth and subsequent chemical modification of poly(glycidyl methacrylate) brushes on silicon wafers. J Mater Chem 14:730–734Google Scholar
  37. 37.
    Xu FJ, Zhong SP, Yung LY, Tong YW, Kang ET, Neoh KG (2006) Thermoresponsive comb-shaped copolymer-Si(100) hybrids for accelerated temperature-dependent cell detachment. Biomaterials 27:1236–1245Google Scholar
  38. 38.
    Barbey R, Klok HA (2010) Room temperature, aqueous post-polymerization modification of glycidyl methacrylate-containing polymer brushes prepared via surface-initiated atom transfer radical polymerization. Langmuir 26:18219–18230Google Scholar
  39. 39.
    Li Y, Benicewicz BC (2008) Functionalization of silica nanoparticles via the combination of surface-initiated RAFT polymerization and click reactions. Macromolecules 41:7986–7992Google Scholar
  40. 40.
    Cullen SP, Mandel IC, Gopalan P (2008) Surface-anchored poly(2-vinyl-4,4-dimethyl azlactone) brushes as templates for enzyme immobilization. Langmuir 24:13701–13709Google Scholar
  41. 41.
    Hensarling RM, Rahane SB, LeBlanc AP, Sparks BJ, White EM, Locklin J, Patton DL (2011) Thiol-isocyanate “click” reactions: rapid development of functional polymeric surfaces. Polym Chem 2:88–90Google Scholar
  42. 42.
    Cai T, Neoh KG, Kang ET (2011) Poly(vinylidene fluoride) graft copolymer membranes with “clickable” surfaces and their functionalization. Macromolecules 44:4258–4268Google Scholar
  43. 43.
    Nozaki K, Sato N, Tonomura Y, Yasutomi M, Takaya H, Hiyama T, Matsubara T, Koga N (1997) Mechanistic aspects of the alternating copolymerization of propene with carbon monoxide catalyzed by Pd(II) complexes of unsymmetrical phosphine-phosphite ligands. J Am Chem Soc 119:12779–12795Google Scholar
  44. 44.
    Angiolini L, Caretti D, Mazzocchetti L, Salatelli E, Willem R, Biesemans M (2006) Cross-linked polystyrene resins containing triorganotin-4-vinylbenzoates: assessment of their catalytic activity in transesterification reactions. J Organomet Chem 691:3043–3052Google Scholar
  45. 45.
    Aamer KA, Tew GN (2007) RAFT polymerization of a novel activated ester monomer and conversion to a terpyridine-containing homopolymer. J Polym Sci A Polym Chem 45:5618–5625Google Scholar
  46. 46.
    Orski SV, Fries KH, Sheppard GR, Locklin J (2010) High density scaffolding of functional polymer brushes: surface initiated atom transfer radical polymerization of active esters. Langmuir 26:2136–2143Google Scholar
  47. 47.
    Gunay KA, Schuwer N, Klok HA (2012) Synthesis and post-polymerization modification of poly(pentafluorophenyl methacrylate) brushes. Polym Chem 3:2186–2192Google Scholar
  48. 48.
    Kessler D, Jochum FD, Choi J, Char K, Theato P (2011) Reactive surface coatings based on polysilsesquioxanes: universal method toward light-responsive surfaces. ACS Appl Mater Interfaces 3:124–128Google Scholar
  49. 49.
    Kessler D, Theato P (2009) Reactive surface coatings based on polysilsesquioxanes: defined adjustment of surface wettability. Langmuir 25:14200–14206Google Scholar
  50. 50.
    Eberhardt M, Theato P (2005) RAFT polymerization of pentafluorophenyl methacrylate: preparation of reactive linear diblock copolymer. Macromol Rapid Commun 26:1488–1493Google Scholar
  51. 51.
    Gibson MI, Frohlich E, Klok HA (2009) Postpolymerization modification of poly(pentafluorophenyl methacrylate): synthesis of a diverse water-soluble polymer library. J Polym Sci A Polym Chem 47:4332–4345Google Scholar
  52. 52.
    Eberhardt M, Mruk R, Zentel R, Theato P (2005) Synthesis of pentafluorophenyl(meth)acrylate polymers: new precursor polymers for the synthesis of multifunctional materials. Eur Polym J 41:1569–1575Google Scholar
  53. 53.
    Li CZ, Benicewicz BC (2005) Synthesis of well-defined polymer brushes grafted onto silica nanoparticles via surface reversible addition-fragmentation chain transfer polymerization. Macromolecules 38:5929–5936Google Scholar
  54. 54.
    Ranjan R, Brittain WJ (2008) Synthesis of high density polymer brushes on nanoparticles by combined RAFT polymerization and click chemistry. Macromol Rapid Commun 29:1104–1110Google Scholar
  55. 55.
    De P, Li M, Gondi SR, Sumerlin BS (2008) Temperature-regulated activity of responsive polymer-protein conjugates prepared by grafting-from via RAFT polymerization. J Am Chem Soc 130:11288–11289Google Scholar
  56. 56.
    Kessler D, Teutsch C, Theato P (2008) Synthesis of processable inorganic-organic hybrid polymers based on poly(silsesquioxanes): grafting from polymerization using ATRP. Macromol Chem Phys 209:1437–1446Google Scholar
  57. 57.
    Kessler D, Theato P (2008) Synthesis of functional inorganic-organic hybrid polymers based on poly(silsesquioxanes) and their thin film properties. Macromolecules 41:5237–5244Google Scholar
  58. 58.
    Tiktopulo EI, Bychkova VE, Ricka J, Ptitsyn OB (1994) Cooperativity of the coil-globule transition in a homopolymer – microcalorimetric study of poly(N-isopropylacrylamide). Macromolecules 27:2879–2882Google Scholar
  59. 59.
    Fujishige S, Kubota K, Ando I (1989) Phase-transition of aqueous-solutions of poly(N-isopropylacrylamide) and poly(N-isopropylmethacrylamide). J Phys Chem 93:3311–3313Google Scholar
  60. 60.
    Barbara PF, Rentzepis PM, Brus LE (1980) Photochemical kinetics of salicylidenaniline. J Am Chem Soc 102:2786–2791Google Scholar
  61. 61.
    Thompson BC, Abboud KA, Reynolds JR, Nakatani K, Audebert P (2005) Electrochromic conjugated N-salicylidene-aniline (anil) functionalized pyrrole and 2,5-dithienylpyrrole-based polymers. New J Chem 29:1128–1134Google Scholar
  62. 62.
    Ledbette JW (1966) Spectroscopic evidence for enol imine-keto enamine tautomerism of N-(O- and P-hydroxybenzylidene) anils in solution. J Phys Chem 70:2245Google Scholar
  63. 63.
    Rissing C, Son DY (2009) Application of thiol-Ene chemistry to the preparation of carbosilane-thioether dendrimers. Organometallics 28:3167–3172Google Scholar
  64. 64.
    Samanta S, Locklin J (2008) Formation of photochromic spiropyran polymer brushes via surface-initiated, ring-opening metathesis polymerization: reversible photocontrol of wetting behavior and solvent dependent morphology changes. Langmuir 24:9558–9565Google Scholar
  65. 65.
    Fries K, Samanta S, Orski S, Locklin J (2008) Reversible colorimetric ion sensors based on surface initiated polymerization of photochromic polymers. Chem Commun 2008(47):6288–6290 doi: 10.1039/B818042CGoogle Scholar
  66. 66.
    Jochum FD, Theato P (2009) Temperature and light sensitive copolymers containing azobenzene moieties prepared via a polymer analogous reaction. Polymer 50:3079–3085Google Scholar
  67. 67.
    Decher G (1997) Fuzzy nanoassemblies: toward layered polymeric multicomposites. Science 277:1232–1237Google Scholar
  68. 68.
    Bertrand P, Jonas A, Laschewsky A, Legras R (2000) Ultrathin polymer coatings by complexation of polyelectrolytes at interfaces: suitable materials, structure and properties. Macromol Rapid Commun 21:319–348Google Scholar
  69. 69.
    Bergbreiter DE, Liao KS (2009) Covalent layer-by-layer assembly-an effective, forgiving way to construct functional robust ultrathin films and nanocomposites. Soft Matter 5:23–28Google Scholar
  70. 70.
    Buck ME, Zhang J, Lynn DM (2007) Layer-by-layer assembly of reactive ultrathin films mediated by click-type reactions of poly(2-alkenyl azlactone)s. Adv Mater 19:3951–3955Google Scholar
  71. 71.
    Peyratout CS, Dahne L (2004) Tailor-made polyelectrolyte microcapsules: from multilayers to smart containers. Angew Chem Int Ed 43:3762–3783Google Scholar
  72. 72.
    Tang ZY, Wang Y, Podsiadlo P, Kotov NA (2006) Biomedical applications of layer-by-layer assembly: from biomimetics to tissue engineering. Adv Mater 18:3203–3224Google Scholar
  73. 73.
    Boudou T, Crouzier T, Ren KF, Blin G, Picart C (2010) Multiple functionalities of polyelectrolyte multilayer films: new biomedical applications. Adv Mater 22:441–467Google Scholar
  74. 74.
    Buck ME, Lynn DM (2011) Layer-by-layer fabrication of covalently crosslinked and reactive polymer multilayers using azlactone-functionalized copolymers: a platform for the design of functional biointerfaces. Adv Eng Mater 13:B343–B352Google Scholar
  75. 75.
    Buck ME, Breitbach AS, Belgrade SK, Blackwell HE, Lynn DM (2009) Chemical modification of reactive multilayered films fabricated from poly(2-alkenyl azlactone)s: design of surfaces that prevent or promote mammalian cell adhesion and bacterial biofilm growth. Biomacromolecules 10:1564–1574Google Scholar
  76. 76.
    Buck ME, Lynn DM (2010) Reactive layer-by-layer assembly of suspended thin films and semipermeable membranes at interfaces created between aqueous and organic phases. Adv Mater 22:994–998Google Scholar
  77. 77.
    Buck ME, Lynn DM (2010) Functionalization of fibers using azlactone-containing polymers: layer-by-layer fabrication of reactive thin films on the surfaces of hair and cellulose-based materials. ACS Appl Mater Interfaces 2:1421–1429Google Scholar
  78. 78.
    Buck ME, Lynn DM (2010) Free-standing and reactive thin films fabricated by covalent layer-by-layer assembly and subsequent lift-off of azlactone-containing polymer multilayers. Langmuir 26:16134–16140Google Scholar
  79. 79.
    Buck ME, Schwartz SC, Lynn DM (2010) Superhydrophobic thin films fabricated by reactive layer-by-layer assembly of azlactone-functionalized polymers. Chem Mater 22:6319–6327Google Scholar
  80. 80.
    Kinsinger MI, Buck ME, Abbott NL, Lynn DM (2010) Immobilization of polymer-decorated liquid crystal droplets on chemically tailored surfaces. Langmuir 26:10234–10242Google Scholar
  81. 81.
    Broderick AH, Azarin SM, Buck ME, Palecek SP, Lynn DM (2011) Fabrication and selective functionalization of amine-reactive polymer multi layers on topographically patterned microwell cell culture arrays. Biomacromolecules 12:1998–2007Google Scholar
  82. 82.
    Saurer EM, Flessner RM, Buck ME, Lynn DM (2011) Fabrication of covalently crosslinked and amine-reactive microcapsules by reactive layer-by-layer assembly of azlactone-containing polymer multilayers on sacrificial microparticle templates. J Mater Chem 21:1736–1745Google Scholar
  83. 83.
    Such GK, Quinn JF, Quinn A, Tjipto E, Caruso F (2006) Assembly of ultrathin polymer multilayer films by click chemistry. J Am Chem Soc 128:9318–9319Google Scholar
  84. 84.
    Kinnane CR, Such GK, Caruso F (2011) Tuning the properties of layer-by-layer assembled poly(acrylic acid) click films and capsules. Macromolecules 44:1194–1202Google Scholar
  85. 85.
    Tang YC, Liu GM, Yu CQ, Wei XL, Zhang GZ (2008) Chemical oscillation induced periodic swelling and shrinking of a polymeric multilayer investigated with a quartz crystal microbalance. Langmuir 24:8929–8933Google Scholar
  86. 86.
    Such GK, Tjipto E, Postma A, Johnston APR, Caruso F (2007) Ultrathin, responsive polymer click capsules. Nano Lett 7:1706–1710Google Scholar
  87. 87.
    Bergbreiter DE, Chance BS (2007) “Click”-based covalent layer-by-layer assembly on polyethylene using water-soluble polymeric reagents. Macromolecules 40:5337–5343Google Scholar
  88. 88.
    Huang CJ, Chang FC (2009) Using click chemistry to fabricate ultrathin thermoresponsive microcapsules through direct covalent layer-by-layer assembly. Macromolecules 42:5155–5166Google Scholar
  89. 89.
    Vestberg R, Malkoch M, Kade M, Wu P, Fokin VV, Sharpless KB, Drockenmuller E, Hawker CJ (2007) Role of architecture and molecular weight in the formation of tailor-made ultrathin multilayers using dendritic macromolecules and click chemistry. J Polym Sci A Polym Chem 45:2835–2846Google Scholar
  90. 90.
    El Haitami AE, Thomann JS, Jierry L, Parat A, Voegel JC, Schaaf P, Senger B, Boulmedais F, Frisch B (2010) Covalent layer-by-layer assemblies of polyelectrolytes and homobifunctional spacers. Langmuir 26:12351–12357Google Scholar
  91. 91.
    Jierry L, Ben Ameur N, Thomann JS, Frisch B, Gonthier E, Voegel JC, Senger B, Decher G, Felix O, Schaaf P, Mesini P, Boulmedais F (2010) Influence of Cu(I)-alkyne pi-complex charge on the step-by-step film buildup through sharpless click reaction. Macromolecules 43:3994–3997Google Scholar
  92. 92.
    De Geest BG, Van Camp W, Du Prez FE, De Smedt SC, Demeester J, Hennink WE (2008) Degradable multilayer films and hollow capsules via a ‘click’ strategy. Macromol Rapid Commun 29:1111–1118Google Scholar
  93. 93.
    Ochs CJ, Such GK, Stadler B, Caruso F (2008) Low-fouling, biofunctionalized, and biodegradable click capsules. Biomacromolecules 9:3389–3396Google Scholar
  94. 94.
    Zhang Y, He H, Gao C, Wu JY (2009) Covalent layer-by-layer functionalization of multiwalled carbon nanotubes by click chemistry. Langmuir 25:5814–5824Google Scholar
  95. 95.
    Rydzek G, Thomann JS, Ben Ameur N, Jierry L, Mesini P, Ponche A, Contal C, El Haitami AE, Voegel JC, Senger B, Schaaf P, Frisch B, Boulmedais F (2010) Polymer multilayer films obtained by electrochemically catalyzed click chemistry. Langmuir 26:2816–2824Google Scholar
  96. 96.
    Seo J, Schattling P, Lang T, Jochum F, Nilles K, Theato P, Char K (2010) Covalently bonded layer-by-layer assembly of multifunctional thin films based on activated esters. Langmuir 26:1830–1836Google Scholar
  97. 97.
    Arnold RM, Huddleston NE, Locklin J (2012) Utilizing click chemistry to design functional interfaces through post-polymerization modification. J Mater Chem 22:19357–19365Google Scholar
  98. 98.
    Orski SV, Fries KH, Sontag SK, Locklin J (2011) Fabrication of nanostructures using polymer brushes. J Mater Chem 21:14135–14149Google Scholar
  99. 99.
    Orski SV, Poloukhtine AA, Arumugam S, Mao LD, Popik VV, Locklin J (2010) High density orthogonal surface immobilization via photoactivated copper-free click chemistry. J Am Chem Soc 132:11024–11026Google Scholar
  100. 100.
    Arnold RM, Locklin J (2013) Self-sorting click reactions that generate spatially controlled chemical functionality on surfaces. Langmuir 29:5920–5926Google Scholar
  101. 101.
    Arnold RM, McNitt CD, Popik VV, Locklin J (2014) Direct grafting of poly(pentafluorophenyl acrylate) onto oxides: versatile substrates for reactive microcapillary printing and self-sorting modification. Chem Commun 50:5307–5309Google Scholar
  102. 102.
    Hensarling RM, Doughty VA, Chan JW, Patton DL (2009) “Clicking” polymer brushes with thiol-yne chemistry: indoors and out. J Am Chem Soc 131:14673–14675Google Scholar
  103. 103.
    Hensarling RM, Hoff EA, LeBlanc AP, Guo W, Rahane SB, Patton DL (2013) Photocaged pendent thiol polymer brush surfaces for postpolymerization modifications via thiol-click chemistry. J Polym Sci A Polym Chem 51:1079–1090Google Scholar
  104. 104.
    Bally F, Cheng K, Nandivada H, Deng XP, Ross AM, Panades A, Lahann J (2013) Co-immobilization of biomolecules on ultrathin reactive chemical vapor deposition coatings using multiple click chemistry strategies. ACS Appl Mater Interfaces 5:9262–9268Google Scholar
  105. 105.
    Spruell JM, Wolffs M, Leibfarth FA, Stahl BC, Heo JH, Connal LA, Hu J, Hawker CJ (2011) Reactive, multifunctional polymer films through thermal cross-linking of orthogonal click groups. J Am Chem Soc 133:16698–16706Google Scholar
  106. 106.
    Rahane SB, Hensarling RM, Sparks BJ, Stafford CM, Patton DL (2012) Synthesis of multifunctional polymer brush surfaces via sequential and orthogonal thiol-click reactions. J Mater Chem 22:932–943Google Scholar
  107. 107.
    Diamanti S, Arifuzzaman S, Elsen A, Genzer J, Vaia RA (2008) Reactive patterning via post-functionalization of polymer brushes utilizing disuccinimidyl carbonate activation to couple primary amines. Polymer 49:3770–3779Google Scholar
  108. 108.
    Slater MD, Frechet JMJ, Svec F (2009) In-column preparation of a brush-type chiral stationary phase using click chemistry and a silica monolith. J Sep Sci 32:21–28Google Scholar
  109. 109.
    Chen Y, Wu M, Wang K, Chen B, Yao S, Zou H, Nie L (2011) Vinyl functionalized silica hybrid monolith-based trypsin microreactor for on line digestion and separation via thiol-ene “click” strategy. J Chromatogr A 1218:7982–7988Google Scholar
  110. 110.
    Wang K, Chen Y, Yang H, Li Y, Nie L, Yao S (2012) Modification of VTMS hybrid monolith via thiol-ene click chemistry for capillary electrochromatography. Talanta 91:52–59Google Scholar
  111. 111.
    Yang HH, Chen YZ, Liu YX, Nie LH, Yao SZ (2013) One-pot synthesis of (3-sulfopropyl methacrylate potassium)-silica hybrid monolith via thiol-ene click chemistry for CEC. Electrophoresis 34:510–517Google Scholar
  112. 112.
    Fournier D, Pascual S, Montembault V, Haddleton DM, Fontaine L (2006) Well-defined azlactone-functionalized (Co)polymers on a solid support: synthesis via supported living radical polymerization and application as nucleophile scavengers. J Comb Chem 8:522–530Google Scholar
  113. 113.
    Tripp JA, Stein JA, Svec F, Frechet JMJ (2000) “Reactive filtration”: use of functionalized porous polymer monoliths as scavengers in solution-phase synthesis. Org Lett 2:195–198Google Scholar
  114. 114.
    Tripp JA, Svec F, Frechet JMJ (2001) Grafted macroporous polymer monolithic disks: a new format of scavengers for solution-phase combinatorial chemistry. J Comb Chem 3:216–223Google Scholar
  115. 115.
    Lucchesi C, Pascual S, Dujardin G, Fontaine L (2008) New functionalized polyHIPE materials used as amine scavengers in batch and flow-through processes. React Funct Polym 68:97–102Google Scholar
  116. 116.
    Guyomard A, Fournier D, Pascual S, Fontaine L, Bardeau JF (2004) Preparation and characterization of azlactone functionalized polymer supports and their application as scavengers. Eur Polym J 40:2343–2348Google Scholar
  117. 117.
    Lucchesi C, Pascual S, Jouanneaux A, Dujardin G, Fontaine L (2007) Tuning the parameters of the suspension polymerization of styrene, divinylbenzene, and N-(p-vinylbenzyl)-4,4-dimethylazlactone. J Polym Sci A Polym Chem 45:3677–3686Google Scholar
  118. 118.
    Dao TTH, Guerrouache M, Carbonnier B (2012) Thiol-yne click adamantane monolithic stationary phase for capillary electrochromatography. Chin J Chem 30:2281–2284Google Scholar
  119. 119.
    Preinerstorfer B, Bicker W, Lindner W, Lammerhofer M (2004) Development of reactive thiol-modified monolithic capillaries and in-column surface functionalization by radical addition of a chromatographic ligand for capillary electrochromatography. J Chromatogr A 1044:187–199Google Scholar
  120. 120.
    Lv Y, Hughes TC, Hao X, Hart NK, Littler SW, Zhang X, Tan T (2010) A novel route to prepare highly reactive and versatile chromatographic monoliths. Macromol Rapid Commun 31:1785–1790Google Scholar
  121. 121.
    Lv Y, Lin Z, Svec F (2012) “Thiol-ene” click chemistry: a facile and versatile route for the functionalization of porous polymer monoliths. Analyst 137:4114–4118Google Scholar
  122. 122.
    Tijunelyte I, Babinot J, Guerrouache M, Valincius G, Carbonnier B (2012) Hydrophilic monolith with ethylene glycol-based grafts prepared via surface confined thiol-ene click photoaddition. Polymer 53:29–36Google Scholar
  123. 123.
    Sun XL, Lin D, He XW, Chen LX, Zhang YK (2010) A facile and efficient strategy for one-step in situ preparation of hydrophobic organic monolithic stationary phases by click chemistry and its application on protein separation. Talanta 82:404–408Google Scholar
  124. 124.
    Sun XL, He XW, Chen LX, Zhang YK (2011) In-column “click” preparation of hydrophobic organic monolithic stationary phases for protein separation. Anal Bioanal Chem 399:3407–3413Google Scholar
  125. 125.
    Salwinski A, Roy V, Agrofoglio LA, Delepee R (2011) In situ one-step method for synthesis of “click”-functionalized monolithic stationary phase for capillary electrochromatography. Macromol Chem Phys 212:2700–2707Google Scholar
  126. 126.
    Xie SF, Svec F, Frechet JMJ (1999) Design of reactive porous polymer supports for high throughput bioreactors: poly(2-vinyl-4,4-dimethylazlactone-co-acrylamide-co-ethyl dimethacrylate) monoliths. Biotechnol Bioeng 62:30–35Google Scholar
  127. 127.
    Peterson DS, Rohr T, Svec F, Frechet JMJ (2002) Enzymatic microreactor-on-a-chip: protein mapping using trypsin immobilized on porous polymer monoliths molded in channels of microfluidic devices. Anal Chem 74:4081–4088Google Scholar
  128. 128.
    Peterson DS, Rohr T, Svec F, Frechet JMJ (2003) Dual-function microanalytical device by in situ photolithographic grafting of porous polymer monolith: integrating solid-phase extraction and enzymatic digestion for peptide mass mapping. Anal Chem 75:5328–5335Google Scholar
  129. 129.
    Geiser L, Eeltink S, Svec F, Frechet JMJ (2008) In-line system containing porous polymer monoliths for protein digestion with immobilized pepsin, peptide preconcentration and nano-liquid chromatography separation coupled to electrospray ionization mass spectroscopy. J Chromatogr A 1188:88–96Google Scholar
  130. 130.
    Logan TC, Clark DS, Stachowiak TB, Svec F, Frechet JMJ (2007) Photopatterning enzymes on polymer monoliths in microfluidic devices for steady-state kinetic analysis and spatially separated multi-enzyme reactions. Anal Chem 79:6592–6598Google Scholar
  131. 131.
    Ekstrom S, Onnerfjord P, Nilsson J, Bengtsson M, Laurell T, Marko-Varga G (2000) Integrated microanalytical technology enabling rapid and automated protein identification. Anal Chem 72:286–293Google Scholar
  132. 132.
    Lazar IM, Ramsey RS, Ramsey JM (2001) On-chip proteolytic digestion and analysis using “wrong-way-round” electrospray time-of-flight mass spectrometry. Anal Chem 73:1733–1739Google Scholar
  133. 133.
    Krenkova J, Svec F (2009) Less common applications of monoliths: IV. Recent developments in immobilized enzyme reactors for proteomics and biotechnology. J Sep Sci 32:706–718Google Scholar
  134. 134.
    Chen HX, Huang T, Zhang XX (2009) Immunoaffinity extraction of testosterone by antibody immobilized monolithic capillary with on-line laser-induced fluorescence detection. Talanta 78:259–264Google Scholar
  135. 135.
    Connolly D, O’Shea V, Clark P, O’Connor B, Paull B (2007) Evaluation of photografted charged sites within polymer monoliths in capillary columns using contactless conductivity detection. J Sep Sci 30:3060–3068Google Scholar
  136. 136.
    Kircher L, Theato P, Cameron NR (2013) Reactive thiol-ene emulsion-templated porous polymers incorporating pentafluorophenyl acrylate. Polymer 54:1755–1761Google Scholar
  137. 137.
    Pelton R (2009) Bioactive paper provides a low-cost platform for diagnostics. Trends Analyt Chem 28:925–942Google Scholar
  138. 138.
    Martinez AW, Phillips ST, Butte MJ, Whitesides GM (2007) Patterned paper as a platform for inexpensive, low-volume, portable bioassays. Angew Chem Int Ed 46:1318–1320Google Scholar
  139. 139.
    Tiller JC, Rieseler R, Berlin P, Klemm D (2002) Stabilization of activity of oxidoreductases by their immobilization onto special functionalized glass and novel aminocellulose film using different coupling reagents. Biomacromolecules 3:1021–1029Google Scholar
  140. 140.
    Turner MB, Spear SK, Holbrey JD, Daly DT, Rogers RD (2005) Ionic liquid-reconstituted cellulose composites as solid support matrices for biocatalyst immobilization. Biomacromolecules 6:2497–2502Google Scholar
  141. 141.
    Boese BJ, Breaker RR (2007) In vitro selection and characterization of cellulose-binding DNA aptamers. Nucleic Acids Res 35:6378–6388Google Scholar
  142. 142.
    Pelegrin M, Marin M, Noel D, Del Rio M, Saller R, Stange J, Mitzner S, Gunzburg WH, Piechaczyk M (1998) Systemic long-term delivery of antibodies in immunocompetent animals using cellulose sulphate capsules containing antibody-producing cells. Gene Ther 5:828–834Google Scholar
  143. 143.
    Ali MM, Aguirre SD, Xu YQ, Filipe CDM, Pelton R, Li YF (2009) Detection of DNA using bioactive paper strips. Chem Commun 2009(43):6640–6642 doi: 10.1039/B911559EGoogle Scholar
  144. 144.
    Kadla JF, Asfour FH, Bar-Nir B (2007) Micropatterned thin film honeycomb materials from regiospecifically modified cellulose. Biomacromolecules 8:161–165Google Scholar
  145. 145.
    Xu WZ, Zhang X, Kadla JF (2012) Design of functionalized cellulosic honeycomb films: site-specific biomolecule modification via “click chemistry”. Biomacromolecules 13:350–357Google Scholar
  146. 146.
    Kolb HC, Sharpless KB (2003) The growing impact of click chemistry on drug discovery. Drug Discov Today 8:1128–1137Google Scholar
  147. 147.
    Bryan MC, Fazio F, Lee HK, Huang CY, Chang A, Best MD, Calarese DA, Blixt O, Paulson JC, Burton D, Wilson IA, Wong CH (2004) Covalent display of oligosaccharide arrays in microtiter plates. J Am Chem Soc 126:8640–8641Google Scholar
  148. 148.
    Wang Q, Chan TR, Hilgraf R, Fokin VV, Sharpless KB, Finn MG (2003) Bioconjugation by copper(I)-catalyzed azide-alkyne [3 + 2] cycloaddition. J Am Chem Soc 125:3192–3193Google Scholar
  149. 149.
    Link AJ, Tirrell DA (2003) Cell surface labeling of Escherichia coli via copper(I)-catalyzed [3 + 2] cycloaddition. J Am Chem Soc 125:11164–11165Google Scholar
  150. 150.
    Lee W, Park SJ (2014) Porous anodic aluminum oxide: anodization and templated synthesis of functional nanostructures. Chem Rev 114:7487–7556Google Scholar
  151. 151.
    Liakos IL, Newman RC, McAlpine E, Alexander MR (2004) Comparative study of self-assembly of a range of monofunctional aliphatic molecules on magnetron-sputtered aluminium. Surf Interface Anal 36:347–354Google Scholar
  152. 152.
    Chen YF, Hu YH, Chou YI, Lai SM, Wang CC (2010) Surface modification of nano-porous anodic alumina membranes and its use in electroosmotic flow. Sens Actuat B Chem 145:575–582Google Scholar
  153. 153.
    Sugnaux C, Lavanant L, Klok HA (2013) Aqueous fabrication of pH-gated, polymer-brush-modified alumina hybrid membranes. Langmuir 29:7325–7333Google Scholar
  154. 154.
    Aryal M, Trivedi K, Hu WW (2009) Nano-confinement induced chain alignment in ordered P3HT nanostructures defined by nanoimprint lithography. ACS Nano 3:3085–3090Google Scholar
  155. 155.
    Haberkorn N, Lechmann MC, Sohn BH, Char K, Gutmann JS, Theato P (2009) Templated organic and hybrid materials for optoelectronic applications. Macromol Rapid Commun 30:1146–1166Google Scholar
  156. 156.
    Gitsas A, Yameen B, Lazzara TD, Steinhart M, Duran H, Knoll W (2010) Polycyanurate nanorod arrays for optical-waveguide-based biosensing. Nano Lett 10:2173–2177Google Scholar
  157. 157.
    Steinhart M, Jia ZH, Schaper AK, Wehrspohn RB, Gosele U, Wendorff JH (2003) Palladium nanotubes with tailored wall morphologies. Adv Mater 15:706–709Google Scholar
  158. 158.
    Dersch R, Steinhart M, Boudriot U, Greiner A, Wendorff JH (2005) Nanoprocessing of polymers: applications in medicine, sensors, catalysis, photonics. Polym Adv Technol 16:276–282Google Scholar
  159. 159.
    Greiner A, Wendorff JH, Yarin AL, Zussman E (2006) Biohybrid nanosystems with polymer nanofibers and nanotubes. Appl Microbiol Biotechnol 71:387–393Google Scholar
  160. 160.
    Hulteen JC, Martin CR (1997) A general template-based method for the preparation of nanomaterials. J Mater Chem 7:1075–1087Google Scholar
  161. 161.
    Huczko A (2000) Template-based synthesis of nanomaterials. Appl Phys A Mater Sci Process 70:365–376Google Scholar
  162. 162.
    Li AP, Muller F, Birner A, Nielsch K, Gosele U (1998) Hexagonal pore arrays with a 50–420 nm interpore distance formed by self-organization in anodic alumina. J Appl Phys 84:6023–6026Google Scholar
  163. 163.
    Ono S, Saito M, Ishiguro M, Asoh H (2004) Controlling factor of self-ordering of anodic porous alumina. J Electrochem Soc 151:B473–B478Google Scholar
  164. 164.
    Masuda H, Fukuda K (1995) Ordered metal nanohole arrays made by a 2-step replication of honeycomb structures of anodic alumina. Science 268:1466–1468Google Scholar
  165. 165.
    Masuda H, Yamada H, Satoh M, Asoh H, Nakao M, Tamamura T (1997) Highly ordered nanochannel-array architecture in anodic alumina. Appl Phys Lett 71:2770–2772Google Scholar
  166. 166.
    Cepak VM, Martin CR (1999) Preparation of polymeric micro- and nanostructures using a template-based deposition method. Chem Mater 11:1363–1367Google Scholar
  167. 167.
    Steinhart M, Wehrspohn RB, Gosele U, Wendorff JH (2004) Nanotubes by template wetting: a modular assembly system. Angew Chem Int Ed 43:1334–1344Google Scholar
  168. 168.
    Steinhart M, Wendorff JH, Wehrspohn RB (2003) Nanotubes a la carte: wetting of porous templates. ChemPhysChem 4:1171–1176Google Scholar
  169. 169.
    Schlitt S, Greiner A, Wendorff JH (2008) Cylindrical polymer nanostructures by solution template wetting. Macromolecules 41:3228–3234Google Scholar
  170. 170.
    Al-Kaysi RO, Ghaddar TH, Guirado G (2009) Fabrication of one-dimensional organic nanostructures using anodic aluminum oxide templates. J Nanomater 2009:1–4Google Scholar
  171. 171.
    Zhang MF, Dobriyal P, Chen JT, Russell TP, Olmo J, Merry A (2006) Wetting transition in cylindrical alumina nanopores with polymer melts. Nano Lett 6:1075–1079Google Scholar
  172. 172.
    Haberkorn N, Nilles K, Schattling P, Theato P (2011) Reactive nanorods based on activated ester polymers: a versatile template-assisted approach for the fabrication of functional nanorods. Polym Chem 2:645–650Google Scholar
  173. 173.
    Lai JJ, Hoffman JM, Ebara M, Hoffman AS, Estournes C, Wattiaux A, Stayton PS (2007) Dual magnetic-/temperature-responsive nanoparticles for microfluidic separations and assays. Langmuir 23:7385–7391Google Scholar
  174. 174.
    Perruchot C, Khan MA, Kamitsi A, Armes SP, von Werne T, Patten TE (2001) Synthesis of well-defined, polymer-grafted silica particles by aqueous ATRP. Langmuir 17:4479–4481Google Scholar
  175. 175.
    Chen XY, Randall DP, Perruchot C, Watts JF, Patten TE, von Werne T, Armes SP (2003) Synthesis and aqueous solution properties of polyelectrolyte-grafted silica particles prepared by surface-initiated atom transfer radical polymerization. J Colloid Interface Sci 257:56–64Google Scholar
  176. 176.
    Li DJ, Sheng X, Zhao B (2005) Environmentally responsive “Hairy” nanoparticles: mixed homopolymer brushes on silica nanoparticles synthesized by living radical polymerization techniques. J Am Chem Soc 127:6248–6256Google Scholar
  177. 177.
    Li DJ, Jones GL, Dunlap JR, Hua FJ, Zhao B (2006) Thermosensitive hairy hybrid nanoparticles synthesized by surface-initiated atom transfer radical polymerization. Langmuir 22:3344–3351Google Scholar
  178. 178.
    Schmidt AM (2005) The synthesis of magnetic core-shell nanoparticles by surface-initiatied ring-opening polymerization of epsilon-Caprolactone. Macromol Rapid Commun 26:93–97Google Scholar
  179. 179.
    Gelbrich T, Feyen M, Schmidt AM (2006) Magnetic thermoresponsive core-shell nanoparticles. Macromolecules 39:3469–3472Google Scholar
  180. 180.
    Kaiser A, Gelbrich T, Schmidt AM (2006) Thermosensitive magnetic fluids. J Phys Condens Matter 18:S2563–S2580Google Scholar
  181. 181.
    Gelbrich T, Reinartz M, Schmidt AM (2010) Active ester functional single core magnetic nanostructures as a versatile immobilization matrix for effective bioseparation and catalysis. Biomacromolecules 11:635–642Google Scholar
  182. 182.
    Erlanger BF, Kokowsky N, Cohen W (1961) The preparation and properties of two new chromogenic substrates of trypsin. Arch Biochem Biophys 95:271–278Google Scholar
  183. 183.
    Roth PJ, Theato P (2008) Versatile synthesis of functional gold nanoparticles: grafting polymers from and onto. Chem Mater 20:1614–1621Google Scholar
  184. 184.
    Roth PJ, Theato P (2012) Covalent attachment of gold nanoparticles to surfaces and polymeric substrates using UV light. Macromol Chem Phys 213:2550–2556Google Scholar
  185. 185.
    Castaneda MT, Merkoci A, Pumera M, Alegret S (2007) Electrochemical genosensors for biomedical applications based on gold nanoparticles. Biosens Bioelectron 22:1961–1967Google Scholar
  186. 186.
    Palecek E, Jelen F (2002) Electrochemistry of nucleic acids and development of DNA sensors. Crit Rev Anal Chem 32:261–270Google Scholar
  187. 187.
    Wang J, Polsky R, Merkoci A, Turner KL (2003) “Electroactive beads” for ultrasensitive DNA detection. Langmuir 19:989–991Google Scholar
  188. 188.
    Grieshaber D, MacKenzie R, Voros J, Reimhult E (2008) Electrochemical biosensors - sensor principles and architectures. Sensors 8:1400–1458Google Scholar
  189. 189.
    Bearinger JP, Voros J, Hubbell JA, Textor M (2003) Electrochemical optical waveguide lightmode spectroscopy (EC-OWLS): a pilot study using evanescent-field optical sensing under voltage control to monitor polycationic polymer adsorption onto indium tin oxide (ITO)-coated waveguide chips. Biotechnol Bioeng 82:465–473Google Scholar
  190. 190.
    Brusatori MA, Van Tassel PR (2003) Biosensing under an applied voltage using optical waveguide lightmode spectroscopy. Biosens Bioelectron 18:1269–1277Google Scholar
  191. 191.
    Yu Y, Jin G (2005) Influence of electrostatic interaction on fibrinogen adsorption on gold studied by imaging ellipsometry combined with electrochemical methods. J Colloid Interface Sci 283:477–481Google Scholar
  192. 192.
    Sun P, Laforge FO, Mirkin MV (2007) Scanning electrochemical microscopy in the 21st century. Phys Chem Chem Phys 9:802–823Google Scholar
  193. 193.
    Edwards MA, Martin S, Whitworth AL, Macpherson JV, Unwin PR (2006) Scanning electrochemical microscopy: principles and applications to biophysical systems. Physiol Meas 27:R63–R108Google Scholar
  194. 194.
    Fortin E, Defontaine Y, Mailley P, Livache T, Szunerits S (2005) Micro-imprinting of oligonucleotides and oligonucleotide gradients on gold surfaces: a new approach based on the combination of scanning electrochemical microscopy and surface plasmon resonance imaging (SECM/SPR-i). Electroanalysis 17:495–503Google Scholar
  195. 195.
    Xiang CH, Xie QJ, Hu JM, Yao S (2005) Symmetric current oscillations at tip and substrate electrodes of scanning electrochemical microscope during silver deposition/stripping. J Electroanal Chem 584:201–209Google Scholar
  196. 196.
    Boldt FM, Heinze J, Diez M, Petersen J, Borsch M (2004) Real-time pH microscopy down to the molecular level by combined scanning electrochemical microscopy/single-molecule fluorescence spectroscopy. Anal Chem 76:3473–3481Google Scholar
  197. 197.
    Shi GD, Garfias-Mesias LF, Smyrl WH (1998) Preparation of a gold-sputtered optical fiber as a microelectrode for electrochemical microscopy. J Electrochem Soc 145:2011–2016Google Scholar
  198. 198.
    Fan FRF, Cliffel D, Bard AJ (1998) Scanning electrochemical microscopy. 37. Light emission by electrogenerated chemiluminescence at SECM tips and their application to scanning optical microscopy. Anal Chem 70:2941–2948Google Scholar
  199. 199.
    Amemiya S, Guo JD, Xiong H, Gross DA (2006) Biological applications of scanning electrochemical microscopy: chemical imaging of single living cells and beyond. Anal Bioanal Chem 386:458–471Google Scholar
  200. 200.
    Michalet X, Pinaud FF, Bentolila LA, Tsay JM, Doose S, Li JJ, Sundaresan G, Wu AM, Gambhir SS, Weiss S (2005) Quantum dots for live cells, in vivo imaging, and diagnostics. Science 307:538–544Google Scholar
  201. 201.
    Reinhard BM, Siu M, Agarwal H, Alivisatos AP, Liphardt J (2005) Calibration of dynamic molecular rule based on plasmon coupling between gold nanoparticles. Nano Lett 5:2246–2252Google Scholar
  202. 202.
    Bunimovich YL, Shin YS, Yeo WS, Amori M, Kwong G, Heath JR (2006) Quantitative real-time measurements of DNA hybridization with alkylated nonoxidized silicon nanowires in electrolyte solution. J Am Chem Soc 128:16323–16331Google Scholar
  203. 203.
    Tans SJ, Verschueren ARM, Dekker C (1998) Room-temperature transistor based on a single carbon nanotube. Nature 393:49–52Google Scholar
  204. 204.
    Avouris P (2004) Carbon nanotube electronics and optoelectronics. MRS Bull 29:403–410Google Scholar
  205. 205.
    Martel R, Schmidt T, Shea HR, Hertel T, Avouris P (1998) Single- and multi-wall carbon nanotube field-effect transistors. Appl Phys Lett 73:2447–2449Google Scholar
  206. 206.
    Chen ZH, Appenzeller J, Lin YM, Sippel-Oakley J, Rinzler AG, Tang JY, Wind SJ, Solomon PM, Avouris P (2006) An integrated logic circuit assembled on a single carbon nanotube. Science 311:1735Google Scholar
  207. 207.
    Yang WR, Thordarson P, Gooding JJ, Ringer SP, Braet F (2007) Carbon nanotubes for biological and biomedical applications. Nanotechnology 18:1–12Google Scholar
  208. 208.
    Martinez MT, Tseng YC, Ormategui N, Loinaz I, Eritja R, Bokor J (2009) Label-free DNA biosensors based on functionalized carbon nanotube field effect transistors. Nano Lett 9:530–536Google Scholar
  209. 209.
    Park HJ, Kim J, Chang JY, Theato P (2008) Preparation of transparent conductive multilayered films using active pentafluorophenyl ester modified multiwalled carbon nanotubes. Langmuir 24:10467–10473Google Scholar
  210. 210.
    Nasreen SA, Sundarrajan S, Nizar SA, Balamurugan R, Ramakrishna S (2013) Advancement in electrospun nanofibrous membranes modification and their application in water treatment. Membranes (Basel) 3:266–284Google Scholar
  211. 211.
    Li LC, Wang BG, Tan HM, Chen TL, Xu JP (2006) A novel nanofiltration membrane prepared with PAMAM and TMC by in situ interfacial polymerization on PEK-C ultrafiltration membrane. J Membr Sci 269:84–93Google Scholar
  212. 212.
    You H, Li X, Yang Y, Wang BY, Li ZX, Wang XF, Zhu MF, Hsiao BS (2013) High flux low pressure thin film nanocomposite ultrafiltration membranes based on nanofibrous substrates. Sep Purif Technol 108:143–151Google Scholar
  213. 213.
    Aerts S, Vanhulsel A, Buekenhoudt A, Weyten H, Kuypers S, Chen H, Bryjak M, Gevers LEM, Vankelecom IFJ, Jacobs PA (2006) Plasma-treated PDMS-membranes in solvent resistant nanofiltration: characterization and study of transport mechanism. J Membr Sci 275:212–219Google Scholar
  214. 214.
    Deng B, Yang XX, Xie LD, Li JY, Hou ZC, Yao S, Liang GM, Sheng KL, Huang Q (2009) Microfiltration membranes with pH dependent property prepared from poly(methacrylic acid) grafted polyethersulfone powder. J Membr Sci 330:363–368Google Scholar
  215. 215.
    Zhang PY, Xu ZL, Yang H, Wei YM, Wu WZ, Chen DG (2013) Preparation and characterization of PVDF-P(PEGMA-r-MMA) ultrafiltration blend membranes via simplified blend method. Desalination 319:47–59Google Scholar
  216. 216.
    Kango S, Kalia S, Celli A, Njuguna J, Habibi Y, Kumar R (2013) Surface modification of inorganic nanoparticles for development of organic-inorganic nanocomposites – a review. Prog Polym Sci 38:1232–1261Google Scholar
  217. 217.
    Thielke MW, Bruckner EP, Wong DL, Theato P (2014) Thiol-ene modification of electrospun polybutadiene fibers crosslinked by UV irradiation. Polymer 55:5596–5599Google Scholar

Copyright information

© Springer International Publishing Switzerland 2015

Authors and Affiliations

  1. 1.Institute for Technical and Macromolecular ChemistryUniversity of HamburgHamburgGermany

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