Metal Catalyzed Reductive C–C Bond Formation

Volume 279 of the series Topics in Current Chemistry pp 139-172


Recent Advances in Alkene Hydroformylation

  • Bernhard BreitAffiliated withInstitut für Organische Chemie und Biochemie, Albert-Ludwigs Universität Freiburg Email author 

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Recent advances in synthetic aspects of the rhodium-catalyzed hydroformylation of alkenes are reviewed. Emphasis is given to practical improvements, efficient new catalysts for regioselective and enantioselective hydroformylation, and to applications of the reaction in organic synthesis. Furthermore, new developments in directed hydroformylation are covered as well as new approaches toward efficient hydroformylation catalysts employing the concept of self-assembly.