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The Development of Artificial Receptors for Small Peptides Using Combinatorial Approaches

  • Carsten Schmuck
  • Peter Wich
Chapter
Part of the Topics in Current Chemistry book series (TOPCURRCHEM, volume 277)

Abstract

In this article we describe some examples how combinatorial libraries are applied in supramolecular chemistry e.g. to identify artificial receptors for peptide binding in aqueous solvent. Whereas in the classical combinatorial approach mainly large but completely random libraries are used, nowadays also the use of small but focused libraries is coming into focus. We discuss the pros and cons of these two different approaches, using examples from literature work and our own studies in this field.

Combinatorial libraries Peptides Receptors Supramolecular chemistry 

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Copyright information

© Springer-Verlag Berlin Heidelberg 2007

Authors and Affiliations

  1. 1.Institut für Organische ChemieUniversität WürzburgWürzburgGermany

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