Classification of Dementia Types from Cognitive Profiles Data
The Cognitive Drug Research (CDR) system is specifically validated for dementia assessment; it consists of a series of computerized tests, which assess the cognitive faculties of the patient to derive a cognitive profile. We use six different classification algorithms to classify clinically diagnosed diseases from their cognitive profiles. Good accuracy was obtained in separating patients affected by Parkinson’s disease from demented patients, and in discriminating between Alzheimer’s disease and Vascular Dementia. However, in discriminating between Parkinson disease with dementia (PDD) and dementia with Lewy bodies (DLB), the accuracy was only slightly superior to chance; the existence of a significant difference in the cognitive profiles of DLB and PDD is indeed questioned in the medical literature.
KeywordsCDR computerized assessment system dementia classification
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- 2.Knopman, D.S., DeKosky, S.T., Cummings, J.L., Chui, H., Corey-Bloom, J., Relkin, G.: Practice parameter: Diagnosis of dementia (an evidence-based review): Report of the quality standards subcommittee of the American academy of neurology. Neurology 56, 1143–1153 (2001)Google Scholar
- 4.Ballard, C., Aarsland, D., McKeith, I., O’Brien, J., Gray, A., Cormack, F., Burn, D., Cassidy, T., Starfeldt, R., Larsen, J., Brown, R., Tovée, M.: Fluctuations in attention - PD dementia vs DLB with parkinsonism. Neurology 59, 1714–1720 (2002)Google Scholar
- 7.Dougherty, J., Kohavi, R., Sahami, M.: Supervised and unsupervised discretization of continuous features. In: International Conference on Machine Learning, pp. 194–202 (1995)Google Scholar