Ecological Impacts of Genetically Modified Crops: Ten Years of Field Research and Commercial Cultivation

  • Olivier SanvidoEmail author
  • Jörg Romeis
  • Franz Bigler
Part of the Advances in Biochemical Engineering/Biotechnology book series (ABE, volume 107)


The worldwide commercial cultivation of genetically modified (GM) crops has raised concerns about potential adverse effects on the environment resulting from the use of these crops. Consequently, the risks of GM crops for the environment, and especially for biodiversity, have been extensively assessed before and during their commercial cultivation. Substantial scientific data on the environmental effects of the currently commercialized GM crops are available today. We have reviewed this scientific knowledge derived from the past 10 years of worldwide experimental field research and commercial cultivation. The review focuses on the currently commercially available GM crops that could be relevant for agriculture in Western and Central Europe (i.e., maize, oilseed rape, and soybean), and on the two main GM traits that are currently commercialized, herbicide tolerance (HT) and insect resistance (IR). The sources of information included peer-reviewed scientific journals, scientific books, reports from regions with extensive GM crop cultivation, as well as reports from international governmental organizations. The data available so far provide no scientific evidence that the cultivation of the presently commercialized GM crops has caused environmental harm. Nevertheless, a number of issues related to the interpretation of scientific data on effects of GM crops on the environment are debated controversially. The present review highlights these scientific debates and discusses the effects of GM crop cultivation on the environment considering the impacts caused by cultivation practices of modern agricultural systems.

Transgenic crops Environmental effects Bt-maize Insect resistance Herbicide tolerance  


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  1. 1.
    Dale PJ, Clarke B, Fontes EMG (2002) Nat Biotechnol 20:567 PubMedCrossRefGoogle Scholar
  2. 2.
    Wolfenbarger LL, Phifer P (2000) Science 290:2088 PubMedADSCrossRefGoogle Scholar
  3. 3.
    Conner AJ, Glare TR, Nap J-P (2003) Plant J 33:19 PubMedCrossRefGoogle Scholar
  4. 4.
    Pretty J (2001) Environ Conserv 28:248 Google Scholar
  5. 5.
    Snow AA, Andow DA, Gepts P, Hallerman EM, Power A, Tiedje JM, Wolfenbarger LL (2005) Ecol Appl 15:377 CrossRefGoogle Scholar
  6. 6.
    Stoate C, Boatman ND, Borralho RJ, Carvalho CR, de Snoo GR, Eden P (2001) J Environ Manage 63:337 PubMedCrossRefGoogle Scholar
  7. 7.
    Hails RS (2002) Nature 418:685 PubMedADSCrossRefGoogle Scholar
  8. 8.
    Robinson RA, Sutherland WJ (2002) J Appl Ecol 39:157 CrossRefGoogle Scholar
  9. 9.
    Chapin FS, Zavaleta ES, Eviner VT, Naylor RL, Vitousek PM, Reynolds HL, Hooper DU, Lavorel S, Sala OE, Hobbie SE, Mack MC, Diaz S (2000) Nature 405:234 PubMedCrossRefGoogle Scholar
  10. 10.
    Tilman D, Cassman KG, Matson PA, Naylor R, Polasky S (2002) Nature 418:671 PubMedADSCrossRefGoogle Scholar
  11. 11.
    Ammann K (2005) Trend Biotechnol 23:388 CrossRefGoogle Scholar
  12. 12.
    McLaughlin A, Mineau P (1995) Agric Ecosyst Environ 55:201 CrossRefGoogle Scholar
  13. 13.
    Walter T, Buholzer S, Kühne A, Schneider K (2005) In: Herzog F, Walter T (eds) Evaluation der Ökomassnahmen Bereich Biodiversität. Agroscope FAL Reckenholz. Eidgenössische Forschungsanstalt für Agrarökologie und Landbau, Zürich (Schriftenreihe der FAL Nr. 56) Google Scholar
  14. 14.
    Chamberlain DE, Fuller RJ, Bunce RGH, Duckworth JC, Shrubb M (2000) J Appl Ecol 37:771 CrossRefGoogle Scholar
  15. 15.
    Royal Society (2003) GM crops, modern agriculture and the environment. The Royal Society, London, p 17 Google Scholar
  16. 16.
    Jaffe G (2004) Transgen Res 13:5 CrossRefGoogle Scholar
  17. 17.
    CFIA (2004) Canadian Food Inspection Agency, Ottawa, p 33 Google Scholar
  18. 18.
    EFSA (2004) Guidance document of the scientific panel on genetically modified organisms for the risk assessment of genetically modified plants and derived food and feed. European Food Safety Authority, Brussels, p 94 Google Scholar
  19. 19.
    EPA (1998) Guidelines for ecological risk assessment. US Environ Protection Agency, Washington, DC, p 80 Google Scholar
  20. 20.
    OECD (1993) Safety considerations for biotechnology: scale-up of crop plants. Organisation for Economic Co-Operation and Development, Paris, p 43 Google Scholar
  21. 21.
    James C (2005) Global status of commercialized biotech/GM crops: 2005, ISAAA Brief No. 34. International Service for the Acquisition of Agri-biotech Applications, Ithaca, NY, p 11 Google Scholar
  22. 22.
    de Maagd RA (2004) In: Nap JPH, Atanassov A, Stiekema WJ (eds) Genomics for biosafety in plant biotechnology. IOS Press, Amsterdam, p 117 Google Scholar
  23. 23.
    Ely S (1993) In: Entwistle PF, Cory JS, Bailey MJ, Higgs S (eds) Bacillus thuringiensis, an environmental biopesticide: theory and practice. Wiley, Chichester, p 105 Google Scholar
  24. 24.
    Shelton AM, Zhao JZ, Roush RT (2002) Ann Rev Entomol 47:845 CrossRefGoogle Scholar
  25. 25.
    Pilcher CD, Rice ME, Obrycki JJ, Lewis LC (1997) J Econ Entomol 90:669 Google Scholar
  26. 26.
    Gonzales-Nunez M, Ortego F, Castanera P (2000) J Econ Entomol 93:459 CrossRefGoogle Scholar
  27. 27.
    Dutton A, Romeis J, Bigler F (2005) Entomol Experiment Appl 114:161 CrossRefGoogle Scholar
  28. 28.
    AGBIOS (2006) Biotech Crop Database. AGBIOS, Merrickville, Ontario Google Scholar
  29. 29.
    Ward DP, de Gooyer TA, Vaughn TT, Head G, McKee MJ, Astwood JD, Pershing JC (2005) In: Vidal S, Kuhlmann U, Edwards CR (eds) Western corn rootworm: ecology and management. CABI Publishing, Wallingford UK, p 239 CrossRefGoogle Scholar
  30. 30.
    Romeis J, Meissle M, Bigler F (2006) Nat Biotechnol 24:63 PubMedCrossRefGoogle Scholar
  31. 31.
    Hilbeck A, Baumgartner M, Fried PM, Bigler F (1998) Environ Entomol 27:480 Google Scholar
  32. 32.
    Hilbeck A, Moar WJ, Pusztai-Carey M, Filippini A, Bigler F (1998) Environ Entomol 27:1255 Google Scholar
  33. 33.
    Hilbeck A, Moar WJ, Pusztai-Carey M, Filippini A, Bigler F (1999) Entomol Experiment Appl 91:305 CrossRefGoogle Scholar
  34. 34.
    Dutton A, Klein H, Romeis J, Bigler F (2002) Ecol Entomol 27:441 CrossRefGoogle Scholar
  35. 35.
    Rodrigo-Simon A, De Maagd RA, Avilla C, Bakker PL, Molthoff J, Gonzalez-Zamora JE, Ferre J (2006) Appl Environ Microbiol 72:1595 PubMedCrossRefGoogle Scholar
  36. 36.
    Romeis J, Dutton A, Bigler F (2004) J Insect Physiol 50:175 PubMedCrossRefGoogle Scholar
  37. 37.
    Dutton A, Romeis J, Bigler F (2003) Biocontrol 48:611 CrossRefGoogle Scholar
  38. 38.
    Eizaguirre M, Albajes R, Lopez C, Eras J, Lumbierres B, Pons X (2006) Transgen Res 15:1 CrossRefGoogle Scholar
  39. 39.
    Pilcher CD, Rice ME, Obrycki JJ (2005) Environ Entomol 34:1302 CrossRefGoogle Scholar
  40. 40.
    Riddick EW, Dively G, Barbosa P (1998) Ann Entomol Soc USA 91:647 Google Scholar
  41. 41.
    Daly T, Buntin GD (2005) Environ Entomol 34:1292 CrossRefGoogle Scholar
  42. 42.
    Naranjo SE (2005) Environ Entomol 34:1193 CrossRefGoogle Scholar
  43. 43.
    Whitehouse MEA, Wilson LJ, Fitt GP (2005) Environ Entomol 34:1224 CrossRefGoogle Scholar
  44. 44.
    Naranjo SE, Head G, Dively GP (2005) Environ Entomol 34:1178 CrossRefGoogle Scholar
  45. 45.
    Clark BW, Phillips TA, Coats JR (2005) J Agric Food Chem 53:4643 PubMedCrossRefGoogle Scholar
  46. 46.
    O'Callaghan M, Glare TR, Burgess EPJ, Malone LA (2005) Ann Rev Entomol 50:271 CrossRefGoogle Scholar
  47. 47.
    Candolfi MP, Brown K, Grimm C, Reber B, Schmidli H (2004) Biocontrol Sci Technol 14:129 CrossRefGoogle Scholar
  48. 48.
    Meissle M, Lang A (2005) Agric Ecosyst Environ 107:359 CrossRefGoogle Scholar
  49. 49.
    Musser FR, Shelton AM (2003) J Econ Entomol 96:71 PubMedCrossRefGoogle Scholar
  50. 50.
    Men XY, Ge F, Edwards CA, Yardim EN (2004) Phytoparasitica 32:246 CrossRefGoogle Scholar
  51. 51.
    Bambawale OM, Singh A, Sharma OP, Bhosle BB, Lavekar RC, Dhandapani A, Kanwar V, Tanwar RK, Rathod KS, Patange NR, Pawar VM (2004) Curr Sci 86:1628 Google Scholar
  52. 52.
    Hagerty AM, Kilpatrick AL, Turnipseed SG, Sullivan MJ, Bridges WC (2005) Environ Entomol 34:105 CrossRefGoogle Scholar
  53. 53.
    Wu KM, Guo YY (2003) Environ Entomol 32:312 CrossRefGoogle Scholar
  54. 54.
    de la Poza M, Pons X, Farinos GP, Lopez C, Ortego F, Eizaguirre M, Castanera P, Albajes R (2005) Crop Protect 24:677 CrossRefGoogle Scholar
  55. 55.
    Head G, Moar M, Eubanks M, Freeman B, Ruberson J, Hagerty A, Turnipseed S (2005) Environ Entomol 34:1257 CrossRefGoogle Scholar
  56. 56.
    Torres JB, Ruberson JR (2005) Environ Entomol 34:1242 CrossRefGoogle Scholar
  57. 57.
    EPA (2001) Biopesticides registration action document – Bacillus thuringiensis plant-incorporated protectants. US Environmental Protection Agency, Washington DC, p 481 Google Scholar
  58. 58.
    Babendreier D, Kalberer NM, Romeis J, Fluri P, Mulligan E, Bigler F (2005) Apidologie 36:585 CrossRefGoogle Scholar
  59. 59.
    Malone LA (2004) Bee World 85:29 Google Scholar
  60. 60.
    Malone LA, Pham-Delegue MH (2001) Apidologie 32:287 CrossRefGoogle Scholar
  61. 61.
    Losey JE, Rayor LS, Carter ME (1999) Nature 399:214 PubMedADSCrossRefGoogle Scholar
  62. 62.
    Hellmich RL, Siegfried BD, Sears MK, Stanley-Horn DE, Daniels MJ, Mattila HR, Spencer T, Bidne KG, Lewis LC (2001) Proc Natl Acad Sci USA 98:11925 PubMedADSCrossRefGoogle Scholar
  63. 63.
    Stanley-Horn DE, Dively GP, Hellmich RL, Mattila HR, Sears MK, Rose R, Jesse LCH, Losey JE, Obrycki JJ, Lewis L (2001) Proc Natl Acad Sci USA 98:11931 PubMedADSCrossRefGoogle Scholar
  64. 64.
    Anderson PL, Hellmich RL, Sears MK, Sumerford DV, Lewis LC (2004) Environ Entomol 33:1109 CrossRefGoogle Scholar
  65. 65.
    Oberhauser KS, Prysby MD, Mattila HR, Stanley-Horn DE, Sears MK, Dively G, Olson E, Pleasants JM, Lam WKF, Hellmich RL (2001) Proc Natl Acad Sci USA 98:11913 PubMedADSCrossRefGoogle Scholar
  66. 66.
    Sears MK, Hellmich RL, Stanley-Horn DE, Oberhauser KS, Pleasants JM, Mattila HR, Siegfried BD, Dively GP (2001) Proc Natl Acad Sci USA 98:11937 PubMedADSCrossRefGoogle Scholar
  67. 67.
    Dively GP, Rose R, Sears MK, Hellmich RL, Stanley-Horn DE, Calvin DD, Russo JM, Anderson PL (2004) Environ Entomol 33:1116 CrossRefGoogle Scholar
  68. 68.
    Baumgarte S, Tebbe CC (2005) Molec Ecol 14:2539 CrossRefGoogle Scholar
  69. 69.
    Saxena D, Flores S, Stotzky G (1999) Nature 402:480 PubMedADSGoogle Scholar
  70. 70.
    Zwahlen C, Hilbeck A, Gugerli P, Nentwig W (2003) Molec Ecol 12:765 CrossRefGoogle Scholar
  71. 71.
    Mendelsohn M, Kough J, Vaituzis Z, Matthews K (2003) Nat Biotechnol 21:1003 PubMedCrossRefGoogle Scholar
  72. 72.
    Dubelman S, Ayden BR, Bader BM, Brown CR, Jiang CJ, Vlachos D (2005) Environ Entomol 34:915 CrossRefGoogle Scholar
  73. 73.
    Saxena D, Stotzky G (2000) FEMS Microbiol Ecol 33:35 PubMedCrossRefGoogle Scholar
  74. 74.
    Stotzky G (2004) Plant Soil 266:77 CrossRefGoogle Scholar
  75. 75.
    Tapp H, Stotzky G (1998) Soil Biol Biochem 30:471 CrossRefGoogle Scholar
  76. 76.
    Venkateswerlu G, Stotzky G (1992) Curr Microbiol 25:225 CrossRefGoogle Scholar
  77. 77.
    Head G, Surber JB, Watson JA, Martin JW, Duan JJ (2002) Environ Entomol 31:30 CrossRefGoogle Scholar
  78. 78.
    Hopkins DW, Gregorich EG (2003) Eur J Soil Sci 54:793 CrossRefGoogle Scholar
  79. 79.
    Herman RA, Evans SL, Shanahan DM, Mihaliak CA, Bormett GA, Young DL, Buehrer J (2001) Environ Entomol 30:642 CrossRefGoogle Scholar
  80. 80.
    Sims SR, Ream JE (1997) J Agric Food Chem 45:1502 CrossRefGoogle Scholar
  81. 81.
    Bruinsma M, Kowalchuk GA, van Veen JA (2003) Biol Fert Soils 37:329 Google Scholar
  82. 82.
    Widmer F (2007) Assessing Effects of Transgenic Crops on Soie Microbial Communities (in this volume). Springer, Heidelberg Google Scholar
  83. 83.
    Cartwright C, Lilley A, Kirton J (2004) Mechanisms for investigating changes in soil ecology due to GMO releases. DEFRA Department for Environment Food and Rural Affairs, London, p 133 Google Scholar
  84. 84.
    Motavalli PP, Kremer RJ, Fang M, Means NE (2004) J Environ Qual 33:816 PubMedCrossRefGoogle Scholar
  85. 85.
    Widmer F, Oberholzer HR (2003) In: Francaviglia R (ed) Agricultural impacts on soil erosion and soil biodiversity: developing indicators for policy analysis. OECD Organisation for Economic Co-operation and Development, Rome, Italy, p 551 Google Scholar
  86. 86.
    Griffiths BS, Caul S, Thompson J, Birch ANE, Scrimgeour C, Andersen MN, Cortet J, Messean A, Sausse C, Lacroix B, Krogh PH (2005) Plant Soil 275:135 CrossRefGoogle Scholar
  87. 87.
    Manachini B, Lozzia GC (2002) Boll Zool Agr Bachic Ser II 34:85 Google Scholar
  88. 88.
    Saxena D, Stotzky G (2001) Soil Biol Biochem 33:1225 CrossRefGoogle Scholar
  89. 89.
    Escher N, Käch B, Nentwig W (2000) Basic Appl Ecol 1:161 CrossRefGoogle Scholar
  90. 90.
    Pont B, Nentwig W (2005) Biocontr Sci Technol 15:341 CrossRefGoogle Scholar
  91. 91.
    Wandeler H, Bahylova J, Nentwig W (2002) Basic Appl Ecol 3:357 CrossRefGoogle Scholar
  92. 92.
    Sims SR, Martin JW (1997) Pedobiologia 41:412 Google Scholar
  93. 93.
    Yu L, Berry RE, Croft BA (1997) J Econ Entomol 90:113 Google Scholar
  94. 94.
    Zwahlen C, Hilbeck A, Howald R, Nentwig W (2003) Molec Ecol 12:1077 CrossRefGoogle Scholar
  95. 95.
    Vercesi ML, Krogh PH, Holmstrup M (2006) Appl Soil Ecol 32:180 CrossRefGoogle Scholar
  96. 96.
    Ellstrand NC (2003) Dangerous liaisons? When cultivated plants mate with their wild relatives. The John Hopkins University Press, Baltimore Google Scholar
  97. 97.
    de Nijs HCM, Bartsch D, Sweet JB (2004) Introgression from genetically modified plants into wild relatives. CABI Publishing, Wallingford UK CrossRefGoogle Scholar
  98. 98.
    Hails RS, Morley K (2005) Trend Ecol Evolut 20:245 CrossRefGoogle Scholar
  99. 99.
    Stewart CN, Halfhill MD, Warwick SI (2003) Nat Rev Genet 4:806 PubMedCrossRefGoogle Scholar
  100. 100.
    Ellstrand NC, Prentice HC, Hancock JF (1999) Ann Rev Ecol Syst 30:539 CrossRefGoogle Scholar
  101. 101.
    GM Sci Review Panel (2003) GM science review: first report. Department of Trade and Industry, London, p 296 Google Scholar
  102. 102.
    Jacot Y, Ammann K (1999) In: Ammann K, Jacot Y, Simonsen V, Kjellson G (eds) Methods for Risk Assessment of Transgenic Plants III. Ecological risks and prospects of transgenic plants, vol 3. Birkhäuser Verlag, Basel, p 99 Google Scholar
  103. 103.
    Mason P, Braun L, Warwick SI, Zhu B, Stewart CN (2003) Environ Biosafe Res 2:263 CrossRefGoogle Scholar
  104. 104.
    Vacher C, Weis AE, Hermann D, Kossler T, Young C, Hochberg ME (2004) Theor Appl Genet 109:806 PubMedCrossRefGoogle Scholar
  105. 105.
    Daniels R, Boffey C, Mogg R, Bond J, Clarke R (2005) The potential for dispersal of herbicide tolerance genes from genetically modified, herbicide tolerant oilseed rape to wild relative. Centre for Ecology and Hydrology (CEH) Dorset, Dorchester UK, p 23 Google Scholar
  106. 106.
    Halfhill MD, Millwood RJ, Raymer PL, Stewart CN (2002) Environ Biosafe Res 1:19 CrossRefGoogle Scholar
  107. 107.
    Halfhill MD, Zhu B, Warwick SI, Raymer PL, Millwood RJ, Weissinger AK, Stewart CN (2004) Environ Biosafe Res 3:73 CrossRefGoogle Scholar
  108. 108.
    Hansen LB, Siegismund HR, Jørgensen RB (2001) Genet Resour Crop Evolut 48:621 CrossRefGoogle Scholar
  109. 109.
    Hansen LB, Siegismund HR, Jørgensen RB (2003) Heredity 91:276 PubMedCrossRefGoogle Scholar
  110. 110.
    Warwick SI, Simard MJ, Legere A, Beckie HJ, Braun L, Zhu B, Mason P, Seguin-Swartz G, Stewart CN (2003) Theor Appl Genet 107:528 PubMedCrossRefGoogle Scholar
  111. 111.
    Moyes CL, Lilley JM, Casais CA, Cole SG, Haeger PD, Dale PJ (2002) Molec Ecol 11:103 CrossRefGoogle Scholar
  112. 112.
    Darmency H, Lefol E, Fleury A (1998) Molec Ecol 7:1467 CrossRefGoogle Scholar
  113. 113.
    Gueritaine G, Bazot S, Darmency H (2003) New Phytologist 158:561 CrossRefGoogle Scholar
  114. 114.
    Gueritaine G, Sester M, Eber F, Chevre AM, Darmency H (2002) Molec Ecol 11:1419 CrossRefGoogle Scholar
  115. 115.
    Reichman JR, Watrud LS, Lee EH, Burdick CA, Bollman MA, Storm MJ, King GA, Mallory-Smith C (2006) Molec Ecol 15:4243 CrossRefGoogle Scholar
  116. 116.
    Rufener A, Mazyad P, Ammann K (1999) In: Ammann K, Jacot Y, Simonsen V, Kjellson G (eds) Methods for risk assessment of transgenic plants III. Ecological risks and prospects of transgenic plants, vol 3. Birkhäuser Verlag, Basel, p 95 Google Scholar
  117. 117.
    Elton CS (1958) The ecology of invasions by animals and plants. Methuen and Co Ltd., London Google Scholar
  118. 118.
    Levine JM, Vila M, D'Antonio CM, Dukes JS, Grigulis K, Lavorel S (2003) Proc Royal Soc Lond Ser B 270:775 CrossRefGoogle Scholar
  119. 119.
    D'Antonio C, Meyerson LA (2002) Restor Ecol 10:703 CrossRefGoogle Scholar
  120. 120.
    Sakai AK, Allendorf FW, Holt JS, Lodge DM, Molofsky J, With KA, Baughman S, Cabin RJ, Cohen JE, Ellstrand NC, McCauley DE, O'Neil P, Parker IM, Thompson JN, Weller SG (2001) Ann Rev Ecol Systemat 32:305 CrossRefGoogle Scholar
  121. 121.
    Levin SA (1988) Trend Biotechnol 6:S47 CrossRefGoogle Scholar
  122. 122.
    Beckie HJ, Seguin-Swartz G, Nair H, Warwick SI, Johnson E (2004) Weed Sci 52:152 CrossRefGoogle Scholar
  123. 123.
    Hall L, Topinka K, Huffman J, Davis L, Good A (2000) Weed Sci 48:688 CrossRefGoogle Scholar
  124. 124.
    Beckie HJ, Warwick SI, Nair H, Seguin-Swartz GS (2003) Ecol Appl 13:1276 CrossRefGoogle Scholar
  125. 125.
    Legere A (2005) Pest Manage Sci 61:292 CrossRefGoogle Scholar
  126. 126.
    Hall LM, Habibur Rahman M, Gulden RH, Thomas AG (2005) In: Gressel J (ed) Crop ferality and volunteerism. CRC Press, Boca Raton, FL, p 59 Google Scholar
  127. 127.
    Crawley MJ, Hails RS, Rees M, Kohn D, Buxton J (1993) Nature 363:620 ADSCrossRefGoogle Scholar
  128. 128.
    Crawley MJ, Brown SL, Hails RS, Kohn DD, Rees M (2001) Nature 409:682 PubMedADSCrossRefGoogle Scholar
  129. 129.
    Warwick S, Stewart CN (2005) In: Gressel J (ed) Crop ferality and volunteerism. CRC Press, Boca Raton, FL, p 9 Google Scholar
  130. 130.
    Heard MS, Rothery P, Perry JN, Firbank LG (2005) Weed Res 45:331 CrossRefGoogle Scholar
  131. 131.
    Watkinson AR, Freckleton RP, Robinson RA, Sutherland WJ (2000) Science 289:1554 PubMedADSCrossRefGoogle Scholar
  132. 132.
    Dewar AM, May MJ, Woiwod IP, Haylock LA, Champion GT, Garner BH, Sands RJN, Qi AM, Pidgeon JD (2003) Proc Royal Soc Lond Ser B 270:335 CrossRefGoogle Scholar
  133. 133.
    Firbank LG, Forcella F (2000) Science 289:1481 PubMedCrossRefGoogle Scholar
  134. 134.
    May MJ, Champion GT, Dewar AM, Qi A, Pidgeon JD (2005) Proc Royal Soc Ser B 272:111 CrossRefGoogle Scholar
  135. 135.
    Squire GR, Brooks DR, Bohan DA, Champion GT, Daniels RE, Haughton AJ, Hawes C, Heard MS, Hill MO, May MJ, Osborne JL, Perry JN, Roy DB, Woiwod IP, Firbank LG (2003) Philos Trans Royal Soc Lond Ser B 358:1779 CrossRefGoogle Scholar
  136. 136.
    Hawes C, Haughton AJ, Osborne JL, Roy DB, Clark SJ, Perry JN, Rothery P, Bohan DA, Brooks DR, Champion GT, Dewar AM, Heard MS, Woiwod IP, Daniels RE, Young MW, Parish AM, Scott RJ, Firbank LG, Squire GR (2003) Philos Trans Royal Soc Lond Ser B 358:1899 CrossRefGoogle Scholar
  137. 137.
    Chassy B, Carter C, McGloughlin M, McHughen A, Parrott W, Preston C, Roush R, Shelton A, Strauss SH (2003) Nat Biotechnol 21:1429 PubMedCrossRefGoogle Scholar
  138. 138.
    Freckleton RP, Sutherland WJ, Watkinson AR (2003) Science 302:994 PubMedCrossRefGoogle Scholar
  139. 139.
    Firbank LG, Heard MS, Woiwod IP, Hawes C, Haughton AJ, Champion GT, Scott RJ, Hill MO, Dewar AM, Squire GR, May MJ, Brooks DR, Bohan DA, Daniels RE, Osborne JL, Roy DB, Black HIJ, Rothery P, Perry JN (2003) J Appl Ecol 40:2 CrossRefGoogle Scholar
  140. 140.
    Carpenter J, Felsot A, Goode T, Hammig M, Onstad D, Sankula S (2002) Comparative environmental impacts of biotechnology-derived and traditional soybean, corn, and cotton crops. Council for Agricultural Science and Technology, Ames, Iowa, p 200 Google Scholar
  141. 141.
    Phipps RH, Park JR (2002) J Animal Feed Sci 11:1 Google Scholar
  142. 142.
    Holland JM (2004) Agric Ecosyst Environ 103:1 MathSciNetCrossRefGoogle Scholar
  143. 143.
    Heap I (2006) The International Survey of Herbicide Resistant Weeds. Google Scholar
  144. 144.
    Owen MDK, Zelaya IA (2005) Pest Manage Sci 61:301 CrossRefGoogle Scholar
  145. 145.
    Bradshaw LD, Padgette SR, Kimball SL, Wells BH (1997) Weed Technol 11:189 Google Scholar
  146. 146.
    CFIA (2003) Technical workshop on the management of herbicide tolerant crops. Canadian Food Inspection Agency, Ottawa, p 28 Google Scholar
  147. 147.
    VanGessel MJ (2001) Weed Sci 49:703 CrossRefGoogle Scholar
  148. 148.
    EPA (2006) Office of Pesticide Programs. Google Scholar
  149. 149.
    Health Canada (2006) Pest Management Regulatory Agency. Google Scholar
  150. 150.
    HRAC (2006) Guideline to the management of herbicide resistance. Herbicide Resistance Action Committee, Brussels, Belgium, Google Scholar
  151. 151.
    Benbrook C (2001) Pesticide Outlook 12:204 CrossRefGoogle Scholar
  152. 152.
    Benbrook C (2003) BioTech InfoNet, p 42 Google Scholar
  153. 153.
    Brimner TA, Gallivan GJ, Stephenson GR (2005) Pest Manage Sci 61:47 CrossRefGoogle Scholar
  154. 154.
    Brookes G, Barfoot P (2005) AgBioForum 8:187 Google Scholar
  155. 155.
    Fernandez-Cornejo J, Mc Bride WD (2002) Economic Research Service. United States Department of Agriculture, Washington, DC, p 61 Google Scholar
  156. 156.
    Duke SO (2005) Pest Manage Sci 61:211 CrossRefGoogle Scholar
  157. 157.
    Qaim M, Traxler G (2005) Agr Econ 32:73 CrossRefGoogle Scholar
  158. 158.
    Trigo EJ, Cap EJ (2003) AgBioForum 6:87 Google Scholar
  159. 159.
    FAO (2004) The state of food and agriculture – agricultural biotechnology, meeting the needs of the poor? Food and Agric Organization of the United Nations, Rome, p 208 Google Scholar
  160. 160.
    Raney T (2006) Curr Opin Biotechnol 17:174 PubMedGoogle Scholar
  161. 161.
    Fitt GP, Wakelyn PJ, Stewart JM, James C, Roupakias D, Hake K, Zafar Y, Pages J, Giband M (2004) Global status and impacts of biotech cotton: report of the second expert panel on biotechnology of cotton. International Cotton Advisory Committee, Washington, DC, p 65 Google Scholar
  162. 162.
    Wu KM, Guo YY (2005) Ann Rev Entomol 50:31 CrossRefGoogle Scholar
  163. 163.
    Pray CE, Huang JK, Hu RF, Rozelle S (2002) Plant J 31:423 PubMedCrossRefGoogle Scholar
  164. 164.
    Hossain F, Pray CE, Lu Y, Huang J, Fan C, Hu R (2004) Int J Occup Environ Health 10:296 PubMedGoogle Scholar
  165. 165.
    Huang JK, Hu RF, Rozelle S, Pray C (2005) Science 308:688 PubMedADSCrossRefGoogle Scholar
  166. 166.
    Bennett R, Morse S, Ismael Y (2003) 7th ICABR International Conference, Ravello, Italy, p 11 Google Scholar
  167. 167.
    Burnside OC (1996) In: Duke SO (ed) Herbicide-resistant crops. CRC Lewis Publishers, Boca Raton, FL, p 391 Google Scholar
  168. 168.
    CCOC (2001) Canola Council of Canada, Winnipeg, p 55 Google Scholar
  169. 169.
    Fawcett R, Towery D (2002) Conservation Technology Information Center, West Lafayette, IN, p 20 Google Scholar
  170. 170.
    Fernandez-Cornejo J, Caswell M (2006) United States Department of Agriculture–Economic Research Service, Washington, DC, p 30 Google Scholar
  171. 171.
    Gianessi LP (2005) Pest Manage Sci 61:241 CrossRefGoogle Scholar
  172. 172.
    Goklany IM (2002) Nat Biotechnol 20:1075 PubMedCrossRefGoogle Scholar
  173. 173.
    Donegan KK, Palm CJ, Fieland VJ, Porteous LA, Ganio LM, Schaller DL, Bucao LQ, Seidler RJ (1995) Appl Soil Ecol 2:111 CrossRefGoogle Scholar
  174. 174.
    Palm CJ, Schaller DL, Donegan KK, Seidler RJ (1996) Can J Microbiol 42:1258 CrossRefGoogle Scholar
  175. 175.
    Sims SR, Holden LR (1996) Environ Entomol 25:659 Google Scholar
  176. 176.
    Mikkelsen TR, Andersen B, Jørgensen RB (1996) Nature 380:31 ADSCrossRefGoogle Scholar
  177. 177.
    Hauser TP, Shaw RG, Østergard H (1998) Heredity 81:429 CrossRefGoogle Scholar
  178. 178.
    Hauser TP, Jørgensen RB, Østergard H (1998) Heredity 81:436 CrossRefGoogle Scholar
  179. 179.
    Snow AA, Andersen B, Jørgensen RB (1999) Mol Ecol 8:605 CrossRefGoogle Scholar
  180. 180.
    Pertl M, Hauser TP, Damgaard C, Jørgensen RB (2002) Heredity 89:212 PubMedCrossRefGoogle Scholar
  181. 181.
    Hauser TP, Damgaard C, Jørgensen RB (2003) Am J Botany 90:571 CrossRefGoogle Scholar
  182. 182.
    Halfhill MD, Sutherland JP, Moon HS, Poppy GM, Warwick SI, Weissinger AK, Rufty TW, Raymer PL, Stewart CN (2005) Mol Ecol 14:3177 PubMedCrossRefGoogle Scholar
  183. 183.
    Ammitzbøll H, Mikkelsen TN, Jørgensen RB (2005) Environ Biosafe Res 4:3 CrossRefGoogle Scholar
  184. 184.
    Rieger MA, Potter TD, Preston C, Powles SB (2001) Theor Appl Genet 103:555 CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2007

Authors and Affiliations

  1. 1.Agroscope Reckenholz-Tänikon Research Station ARTZurichSwitzerland

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