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Future Aspects of Bioprocess Monitoring

  • Thomas Becker
  • Bernd Hitzmann
  • K. Muffler
  • Ralf Pörtner
  • Kenneth F. Reardon
  • Frank Stahl
  • Roland Ulber
Chapter
Part of the Advances in Biochemical Engineering/Biotechnology book series (ABE, volume 105)

Abstract

Nature has the impressive ability to efficiently and precisely control biological processes by applying highly evolved principles and using minimal space and relatively simple building blocks. The challenge is to transfer these principles into technically applicable and precise analytical systems that can be used for many applications. This article summarizes some of the new approaches in sensor technology and control strategies for different bioprocesses such as fermentations, biotransformations, and downstream processes. It focuses on bio- and chemosensors, optical sensors, DNA and protein chip technology, software sensors, and modern aspects of data evaluation for improved process monitoring and control.

Biosensors Microarray technologies Process control Process monitoring Software sensors 

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Copyright information

© Springer-Verlag Berlin Heidelberg 2006

Authors and Affiliations

  • Thomas Becker
    • 1
  • Bernd Hitzmann
    • 2
  • K. Muffler
    • 5
  • Ralf Pörtner
    • 3
  • Kenneth F. Reardon
    • 4
  • Frank Stahl
    • 2
  • Roland Ulber
    • 5
  1. 1.Universität HohenheimProcess AnalysisStuttgartGermany
  2. 2.Institute of Technical ChemistryUniversity of HannoverHannoverGermany
  3. 3.Hamburg University of TechnologyBioprocess and Biochemical EngineeringHamburgGermany
  4. 4.Colorado State UniversityDepartment of Chemical EngineeringColoradoUSA
  5. 5.University of KaiserslauternFaculty of Mechanical and Process EngineeringKaiserslauternGermany

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