The Neglected Tropical Diseases: The Ancient Afflictions of Stigma and Poverty and the Prospects for their Control and Elimination

Conference paper
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 582)


Visceral Leishmaniasis Lymphatic Filariasis Buruli Ulcer Hookworm Infection Melinda Gate Foundation 
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  1. Bleakley, H. (2003). Disease and development: evidence from the American South. Journal of the European Economic Association. 1, 376–386.CrossRefGoogle Scholar
  2. Ceccarelli, G. (1994). Infettivologia e parasssitologia nella Bivvia. Minerva Medica. 85, 417–422.PubMedGoogle Scholar
  3. Dirckx, J.H. (1985). The biblical plague of “hemorrhoids”. An outbreak of bilharziasis. American Journal of Dermatopathology. 7, 31–36.CrossRefGoogle Scholar
  4. Ekwanzala, M., Pepin, J., Khonde, N., Molisho, S., Bruneel, H., and De Wals, P. (1996). In the heart of darkness: sleeping sickness in Zaire. Lancet. 348, 1427–1430.PubMedCrossRefGoogle Scholar
  5. Fenwick, A., Molyneux, D., Nantulya, V. (2005). Achieving the millennium development goals. Lancet. 365, 1029–1030.PubMedGoogle Scholar
  6. Frick, K.D., Hanson, C.L., and Jacobson, G.A. (2003). Global burden of trachoma and economics of the disease. American Journal of Tropical Medicine and Hygiene. 69, 1–10.PubMedGoogle Scholar
  7. Grove, D.I. (1990). A History of Human Helminthology. CAB International, pp. 209, 469, 521, and 616.Google Scholar
  8. Harrison, G. (1978). Mosquitoes, Malaria & Man: A History of the Hostilities since 1880. New York: E.P. Dutton, pp. 242–54.Google Scholar
  9. Hopkins, D.R., Ruiz-Tiben, E., Diallo, N., Withers, P.C. Jr., and Maguire, J.H. (2002). Drancunculiasis eradication: and now, Sudan. American Journal of Tropical Medicine and Hygiene. 67, 415–422.PubMedGoogle Scholar
  10. Hotez, P.J. (2001). Vaccines as instruments of foreign policy. EMBO reports. 2, 862–868.PubMedCrossRefGoogle Scholar
  11. Hotez, P.J. (2004a). Should we establish a North American school of global health sciences? American Journal of Medical Sciences. 328, 71–77.CrossRefGoogle Scholar
  12. Hotez, P.J. (2004b). The National Institutes of Health roadmap and the developing world. Journal of Investigative Medicine. 52, 246–247.PubMedGoogle Scholar
  13. Hotez, P.J., Brooker, S., Bethony, J.M., Bottazzi, M.E., Loukas, A., and Xiao, S.H. (2004a). Hookworm infection. New England Journal of Medicine. 351, 799–807.PubMedCrossRefGoogle Scholar
  14. Hotez, P.J., Remme, H., Buss, P., Alleyne, G., Morel, C., and Breman, J. (2004b). Combating tropical communicable diseases: workshop report of the disease control priorities project. Clinical Infectious Diseases. 38, 871–878.PubMedCrossRefGoogle Scholar
  15. Hotez, P.J., Bethony, J., Brooker, S., and Albonico, M. (2005). Eliminating neglected diseases in Africa. Lancet. 365, 2089.PubMedCrossRefGoogle Scholar
  16. Hulse, E.V. (1971). Joshua’s curse and the abandonment of ancient Jericho: schistosomiasis as a possible medical explanation. Med. Hist. 15, 376–386.PubMedGoogle Scholar
  17. King, C.H., Dickman, K., Tisch, D.J. (2005). Reassessment of the cost of chronic helmintic infection: a meta-analysis of disability-related outcomes in endemic schistosomiasis. Lancet. 365, 1561–1569.PubMedCrossRefGoogle Scholar
  18. Kremer, M. and Glennerster. (2004). Strong Medicine, Creating Incentives for Pharmaceutical Research on Neglected Diseases. Princeton University Press. pp. 25–64.Google Scholar
  19. Levine, R. and the What Works Working Group. (2004a). Millions Saved, Proven Successes in Global Health, Case 6, Controlling Onchocerciasis in Sub-Saharan Africa, Center for Global Development, pp. 57–64.Google Scholar
  20. Levine, R. et al. (2004b). Millions Saved, Case 11, Controlling Chagas Disease in the Southern Cone of South America, pp. 99–104.Google Scholar
  21. Little, M.P., Breitling, L.P., Basanez, M.G., Alley, E.S., and Boatin, B.A. (2004). Association between microfilarial load and excess mortality in onchocerciasis: an epidemiological study. Lancet. 363, 1514–1521.PubMedCrossRefGoogle Scholar
  22. Lockwood, D.N. and Suneetha, S. (2005). Leprosy: too complex a disease for a simple elimination paradigm. Bulletin of the World Health Organization. 83, 230–235.PubMedGoogle Scholar
  23. Mecaskey, J.W., Knirsch, C.A., Kumaresan, J.A., and Cook, J.A. (2003). The possibility of eliminating blinding trachoma. Lancet. 3, 728–734.CrossRefGoogle Scholar
  24. Medecins Sans Frontieres. (2001). Fatal Imbalance, The Crisis in Research and Development for Drugs for Neglected Diseases. Medecins Sans Frontieres Access to Essential Medicines Campaign and the Drugs for Neglected Diseases Working Group, p. 12.Google Scholar
  25. Molyneux, D.H. (1997). Patterns of change in vector-borne diseases. Annals of Tropical Medicine and Parasitology. 91, 827–839.PubMedCrossRefGoogle Scholar
  26. Molyneux, D.H. (2004). “Neglected” diseases but unrecognized successes — challenges and opportunities for infectious disease control. Lancet. 364, 380–383.PubMedCrossRefGoogle Scholar
  27. Molyneux, D.H. and Nantulya, V.M. (2004). Linking disease control programmes in rural Africa: a pro-poor strategy to reach Abuja targets and millennium development goals. BMJ. 328, 1129–1132.PubMedCrossRefGoogle Scholar
  28. Molyneux, D.H. and Zagaria, N. (2002). Lymphatic filariasis elimination: progress in global programme development. Annals of Tropical Medicine and Parasitology. 96Suppl 2, S15–40.PubMedCrossRefGoogle Scholar
  29. Molyneux, D.H., Hopkins, D.R., and Zagaria, N. (2004). Disease eradication, elimination and control: the need for accurate and consistent usage. Trends in Parasitology. 20, 347–351.PubMedCrossRefGoogle Scholar
  30. Molyneux, D.H., Hotez, P.J., and Fenwick, A. (2005). “Rapid-impact Interventions”: How a policy of integrated control for Africa’s neglected tropical diseases could benefit the poor. PLoS Medicine, 2: e336.PubMedCrossRefGoogle Scholar
  31. Morel, C.M., Acharya, T., Broun, D., Dangi, A., Elias, C., Ganguly, N.K., Gardner, C.A., Gupta, R.K., Haycock, J., Heher, A.D., Keusch, G.T., Hotez, P.J., Krattiger, A.F., Kreutz, F.T., Lall, S., Lee, K., Mahoney, R., Martinez-Palomo, A., Mashelkar, R.A., Matlin, S., Min, H.K., Mzimba, M., Oehler, J., Pick, W., Ridley, R.G., Senanayake, P., Singer, P., and Yun, M.Y. (2005). Health innovation: the neglected capacity of developing countries to address neglected diseases. Science. 309, 401–404.PubMedCrossRefGoogle Scholar
  32. Murray, C.J.L. (1996). Rethinking DALYs. In: The Global Burden of Disease (Murray, C.J.L. and Lopez, A.D., eds.), Global Burden of Disease and Injury Series, Harvard School of Public Health on behalf of the WHO and World Bank, Harvard University Press.Google Scholar
  33. Ostrer, B.S. (2002). Leprosy: medical views of Leviticus Rabba. Early Science and Medicine. 7, 138–154.PubMedGoogle Scholar
  34. Pecoul, B., Chirac, P., Trouiller, P., and Pond, J. (1999). Access to essential drugs in poor countries: a lost battle? Journal of the American Medical Association. 281, 361–367.PubMedCrossRefGoogle Scholar
  35. Ramaiah, K.D., Das, P.K., Michael, E., and Guyatt, H. (2000). The economic burden of lymphatic filariasis in India. Parasitol Today. 16, 251–253.PubMedCrossRefGoogle Scholar
  36. Widdus, R. and White, K. (2004). Combating Diseases Associated with Poverty, Financing Strategies for Product Development and the Potential Role of Public-Private-Partnerships, The Initiative on Public-Private-Partnerships for Health (IPPH), pp. 1–10.Google Scholar
  37. World Health Organization. (2003). Communicable diseases 2002: global defence against the infectious disease threat (ed. Kindhauser, M.K.), Geneva, pp. 106–107.Google Scholar

Copyright information

© Springer Science+Business Media, LLC 2006

Authors and Affiliations

  1. 1.Department of Microbiology, Immunology and Tropical MedicineThe George Washington University and Sabin Vaccine InstituteWashingtonUSA
  2. 2.Task Force for Child SurvivalEmory UniversityAtlantaUSA
  3. 3.Schistosomiasis Control Initiative, Department of Infectious Disease EpidemiologyImperial CollegeLondonUK
  4. 4.Lymphatic Filariasis Support CentreLiverpool School of Tropical MedicineLiverpoolUK

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