Epidemiology of Cancer and Aging

  • Lodovico Balducci
  • Matti Aapro
Part of the Cancer Treatment and Research book series (CTAR, volume 124)


A review of the epidemiology of cancer and age allows concludes:
  • Age is a risk factor both for cancer and carcinogenesis, at least up to age 95;

  • Multiple primary malignancies are more common in older individuals. In many case each of these neoplasms is amenable to cure or life-prolonging treatment. Possible exceptions include localized low grade prostate cancer in men aged 70 plus and smoldering acute leukemia

  • The biological behavior of cancer may be altered with age: in some cases the neoplasm may become more resistant to chemotherapy, in other cases more aggressive and in other cases more indolent;

  • Cancer is prevalently a disease of healthy elderly individuals whose life expectancy and quality of life may be compromised by cancer.


Breast Cancer Renal Cell Carcinoma Clin Oncol Natl Cancer Inst Comprehensive Geriatric Assessment 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science + Business Media, Inc. 2005

Authors and Affiliations

  • Lodovico Balducci
    • 1
    • 2
  • Matti Aapro
    • 3
  1. 1.Senior Adult Oncology ProgramH. Lee Moffitt Cancer Center and Research InstituteTampa
  2. 2.University of South Florida College of MedicineTampa
  3. 3.Multidisciplinary Oncology InstituteClinique de GenolierSwitzerland

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