Pneumonia Caused by Chlamydia pneumoniae
Chapter
Conclusions
A lot of circumstantial evidence now suggests that C. pneumoniae infection is important in patients with CAP: it is commonly present when looked for, it often coexists with bacterial pathogens, it may lead to more complicated course when not treated in the presence of bacterial copathogens, and outcomes, including mortality, are improved if macrolides are incorporated in CAP therapy regimens. Future studies are needed to document the role of this organism more clearly. This would require routine serologic testing, along with cultures and molecular biology techniques, to confirm the high frequency of infection with this organism. In addition, it would be necessary to conduct outcome studies that correlate the use of therapy for C. pneumoniae with improved outcomes in patients who are actually documented to have CAP due to this organism. In the meantime, it is reasonable to suggest empirical treatment of patient with CAP with drugs active against C. pneumoniae, such as macrolides alone or in combination with beta-lactams, or new fluoroquinolones (levafloxacin, gatifloxacin, and moxifloxacin).
Keywords
Nursing Home Streptococcus Pneumoniae Mycoplasma Pneumoniae Microbial Etiology Erythromycin Estolate
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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