Metabolism of Arsenic from Seaweed by Man and Animals
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The arsenosugars in the seaweed were absorbed by humans as well as by the NR sheep. The sheep especially, show tremendously high concentrations of arsenic in the wool and in the urine. Furthermore, the arsenosugars undergo transformation reactions, the metabolites of the arsenosugars XII, XI, and X are the excreted DMAA, MMAA and TMA+. This raises the question; can the concentration of DMAA be used as a bioindicator for the exposure of humans and sheep to inorganic arsenic if the consumption of arsenosugar containing food increases also the level of DMAA in the urine?
KeywordsInductively Couple Plasma Mass Spectrometry Malonic Acid Arsenic Species Inorganic Arsenic Arsenic Content
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- Chappell, W.R., Abernathy, C.O., and Cothern, C.R. (eds.), 1994, Arsenic Exposure and health, Science and Technology Letters, Northwood.Google Scholar