Measurement of Alkali Labile DNA Damage and Cross-Links Following 2450 MHz Microwave and Low Dose Gamma Irradiation In Vitro
As used in our laboratory, the alkaline comet assay is able to detect the alkaline labile DNA damage induced by doses of ionizing radiation as low as 1 cGy and DNA cross-links induced by 1 mM of CDDP. However, neither DNA damage nor DNA cross-links could be detected after a 2-hour exposure to 2450 MHz CW microwave at a SAR of 1.9 W/kg. Thus the difference between our results and those of Lai and Singh cannot be due to differences in the sensitivity of the assay or the ability to detect DNA cross-links.
KeywordsComet Assay Specific Absorption Rate Alkaline Comet Assay Microwave Exposure Comet Length
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