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Measurement of Alkali Labile DNA Damage and Cross-Links Following 2450 MHz Microwave and Low Dose Gamma Irradiation In Vitro

  • I. Lagroye
  • B. Wettring
  • E. G. Moros
  • W. L. Straube
  • W. F. Pickard
  • J. L. Roti Roti

Conclusions

As used in our laboratory, the alkaline comet assay is able to detect the alkaline labile DNA damage induced by doses of ionizing radiation as low as 1 cGy and DNA cross-links induced by 1 mM of CDDP. However, neither DNA damage nor DNA cross-links could be detected after a 2-hour exposure to 2450 MHz CW microwave at a SAR of 1.9 W/kg. Thus the difference between our results and those of Lai and Singh cannot be due to differences in the sensitivity of the assay or the ability to detect DNA cross-links.

Keywords

Comet Assay Specific Absorption Rate Alkaline Comet Assay Microwave Exposure Comet Length 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Kluwer Academic Publishers 2002

Authors and Affiliations

  • I. Lagroye
  • B. Wettring
  • E. G. Moros
  • W. L. Straube
  • W. F. Pickard
  • J. L. Roti Roti

There are no affiliations available

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