Examination of Regulatory Cross-talk Between the Decay Accelerating Factor-binding Fimbrial/Afimbrial Adhesins and Type I Fimbriae

  • Nicola Holden
  • Claire Cotterill
  • David Gally


  1. The revised sequence of DaaA means that the protein is 98% identical to the afimbrial adhesin regulator AFAA-III.

  2. While PapB repressed FimB OFF to ON switching in strain AAEC370A,this was not the case for DaaA.

  3. PapB,but not DaaA,reduced the level of expression of type 1 fimbriae,in static LB media.

  4. Attention is now focused on the amino terminus of the PapB protein as the possible domain involved in cross talk with type 1 fimbriae.



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Copyright information

© Kluwer Academic Publishers 2002

Authors and Affiliations

  • Nicola Holden
    • 1
  • Claire Cotterill
    • 1
  • David Gally
    • 1
  1. 1.Department of VeterinaryPathology, Royal (Dick) School of Veterinary StudiesUniversity of EdinburghEdinburghUK

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