Cell-Cell Contact Between Lymphocytes and Fibroblast-Like Synovioctyes Induces Lymphocytic Expression of Aminopeptidase n/cd13 and Results in Lymphocytic Activation

  • Dagmar Riemann
  • Jana Röntsch
  • Bettina Hause
  • Jürgen Langner
  • Astrid Kehlen
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 477)

Key words

cell-cell contact aminopeptidase CD13 synoviocytes 

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References

  1. Bhat, N.K. et al., 1989, Expression of ets genes in mouse thymocyte subsets and T cells, J. Immunol 142: 672–678.PubMedGoogle Scholar
  2. Entschladen, F. et al., 1997, Differential requirement of protein tyrosine kinases and protein kinase C in the regulation of T cell locomotion in three-dimensional collagen matrices. J. Immunol 159, 3203–3210.PubMedGoogle Scholar
  3. Esparza J, et al., 1999, Fibronectin upregulates gelatinase B (MMP-9) and induces coordinated expression of gelatinase A (MMP-2) and its activator MT1-MMP (MMP-14) by human T lymphocyte cell lines. A process repressed through RAS/MAP kinase signaling pathways. Blood 94:2754–66.PubMedGoogle Scholar
  4. Holoshitz, J. et al., 1991, T lymphocyte-synovial fibroblast interactions induced by mycobacterial proteins in rheumatoid arthritis. Arthritis Rheum. 34: 679–686.PubMedGoogle Scholar
  5. Kehlen, A. et al., 1998, Regulation of the expression of aminopeptidase A, aminopeptidase N/CD13 and dipeptidylpeptidase IV/CD26 in renal carcinoma cells and renal tubular epithelial cells by cytokines and cAMP-increasing mediators. Clin. Exp. Immunol. 111: 435–441.CrossRefPubMedGoogle Scholar
  6. Kobayashi, I., and Ziff, M., 1973, Electron microscopic, studies of lymphoid cells in the rheumatoid synovial membrane. Arthritis Rheum. 16: 471–486.PubMedGoogle Scholar
  7. Maranto, A.R. and Schoen, F.J., 1988, Phosphatase enzyme activity is retained in glutaraldehyde treated bioprosthetic heart valves. ASAIO Trans 34: 827–830.PubMedGoogle Scholar
  8. Mauch, C. et al., 1989, Collagenase gene expression in fibroblasts is regulated by a three-dimensional contact with collagen. FEBS Lett. 250: 301–305.CrossRefPubMedGoogle Scholar
  9. Riemann, D. et al., 1997, Induction of aminopeptidase N/CD13 on human lymphocytes after adhesion to fibroblast-like synoviocytes, endothelial cells, epithelial cells, and monocytes/macrophages. J. Immunol. 158: 3425–3432.PubMedGoogle Scholar
  10. Riemann, D., et al., 1999; CD 13-not just a marker in leukemia typing. Immunol. Today 20: 83–88.CrossRefPubMedGoogle Scholar
  11. Schwachula, A. et al., 1994, Characterization of the phenotype and functional properties of fibroblast-like synoviocytes in comparison to skin fibroblasts and umbilical vein endothelial cells. Immunobiology 190: 67–92.PubMedGoogle Scholar
  12. Shapiro, L. H. et al., 1991, Separate promoters control transcription of the human aminopeptidase N gene in myeloid and intestinal epithelial cells. J. Biol. Chem. 266: 11999–2007.PubMedGoogle Scholar
  13. Shapiro, L. H. et al., 1995, Myb and Ets proteins cooperate to transactivate an early myeloid gene. J. Biol. Chem. 270: 8763–8771.PubMedGoogle Scholar
  14. Thiele, K. et al., 2000, Cell-cell contact of human T cells with fibroblasts changes lymphocytic mRNA expression: Increased mRNA expression of interleukin-17 and interleukin-17 receptor, Eur. Cytokine Network 11: in press.Google Scholar
  15. Van Hal, T.T. et al., 1994, Potential indirect anti-inflammatory effects of IL-4. Stimulation of human monocytes, macrophages, and endothelial cells by IL-4 increases aminopeptidase N activity (CD13; EC 3.4.11.2). J. Immunol. 153: 2718–2728.PubMedGoogle Scholar
  16. Wasylyk, B. et al., 1998, Ets transcription factors: nuclear effectors of the Ras-MAP-kinase signaling pathway. TIBS 23: 213–216.PubMedGoogle Scholar

Copyright information

© Kluwer Academic Publishers 2002

Authors and Affiliations

  • Dagmar Riemann
    • 1
  • Jana Röntsch
    • 1
  • Bettina Hause
    • 2
  • Jürgen Langner
    • 1
  • Astrid Kehlen
    • 1
  1. 1.Institute of Medical ImmunologyMartin Luther University Halle-Wittenberg
  2. 2.Institute of Plant Biochemistry HalleGermany

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