Oxygen Sensing pp 697-704 | Cite as

Characteristics of Carotid Body Chemosensitivity in the Mouse

Baseline Studies for Future Experiments with Knockout Animals
  • L. He
  • J. Chen
  • B. Dinger
  • S. Fidone
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 475)

Keywords

Tyrosine Hydroxylase Atrial Natriuretic Peptide Carotid Body Glomus Cell Carotid Sinus Nerve 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Acker, H., 1994, Mechanisms and meaning of cellular oxygen sensing in the organism. Respir. Physiol. 95(1): 1–10.Google Scholar
  2. Ahluwalia, A., DeFelipe, C., O’Brien, J., Hunt, S.P., and Perretti, M., 1998, Impaired IL-lbeta-induced neutrophil accumulation in tachykinin NK1 receptor knockout mice. Br. J. Pharmacol. 124(6): 1013–1015.Google Scholar
  3. Chen, J., He, L., Dinger, B., and Fidone, S., 1999, Stimulus specific signaling pathways in rabbit carotid body chemoreceptors. Neurosci. (in press).Google Scholar
  4. Gonzalez, C., Almaraz, L., Obeso, A., and Rigual, R., 1994, Carotid body chemoreceptors: from natural stimuli to sensory discharges. Physiol. Rev. 74: 829–898.Google Scholar
  5. Gonzalez, C., Dinger, B.G., and Fidone, S.J., 1995, Mechanisms of carotid body chemoreception. In Regulation of Breathing (J.A. Dempsey and A.I. Pack, eds.), Marcel Dekker, Inc., New York, pp. 391–471.Google Scholar
  6. He, L., Chen, J., Dinger, B., Stensaas, L., and Fidone,, 1996, S. Endothelin modulates chemoreceptor cell function in mammalian carotid body. In Frontiers in Arterial Chemoreception (P. Zapata P, C. Eyzaguirre and R.W. Torrance RW, eds.), Plenum Press, New York, pp. 305–311.Google Scholar
  7. Kline, D.D., Yang, T., Huang, P.L., and Prabhakar, N.R., 1998, Altered respiratory responses to hypoxia in mutant mice deficient in neuronal nitric oxide synthase. J. Physiol. 511,1: 273–287.Google Scholar
  8. Lopez, M.J., Wong, S.K., Kishimoto, I., Dubois, S., Mach, V., Friesen, J., Garbers, D.L., and Beuve, A., 1995, Salt-resistant hypertension in mice lacking the guanylyl cyclase-A receptor for atrial natriuretic peptide. Nature 378(6552): 65–68.Google Scholar
  9. Melo, L.G., Veress, A.T., Chong, C.K., Pang, S.C., Flynn, T.G., and Sonnenberg, H., 1998, Salt-sensitive hypertension in ANP knockout mice: potential role of abnormal plasma renin activity. Am. J. Physiol. 274(1 Pt 2): R255–261.Google Scholar
  10. Missias, A.C., Mudd, J., Cunningham, J.M., Steinbach, J.H., Merlie, J.P., and Sanes, J.R., 1997, Deficient development and maintenance of postsynaptic specializations in mutant mice lacking an ‘adult’ acetylcholine receptor subunit. Development 124(24): 5075–5086.Google Scholar
  11. Morita, H., Kurihara, H., Kurihara, Y., Shindo, T., Kuwaki, T., Kumada, M., and Yazaki, Y., 1998, Systemic and renal response to salt loading in endothelin-1 knockout mice. J. Cardiovasc. Pharmacol. 31 Suppl 1: S557–S560.Google Scholar
  12. Orr-Urtreger, A., Goldner, F.M., Saeki, M., Lorenzo, I., Goldberg, L., DeBiasi, M., Dani, J.A., Patrick, J.W., and Beaudet, A.L., 1997, Mice deficient in the alpha7 neuronal nicotinic acetylcholine receptor lack alpha-bungarotoxin binding sites and hippocampal fast nicotinic currents. J. Neurosci. 17(2): 9165–9171.Google Scholar
  13. Picciotto, M.R., and Wickman, K., 1998, Using knockout and transgenic mice to study neurophysiology and behavior. Physiol. Rev. 78(4): 1131–1163.Google Scholar
  14. Prabhakar, N.R., 1994, Neurotransmitters in the carotid body. Adv. Exp. Med. Biol. 360: 57–70.Google Scholar
  15. Stensaas, L.J., Wang, Z.-Z., Dinger, B., & Fidone, S. (1991). Alteration of atrial natriuretic peptide (ANP) immunostaining in the rat carotid body evoked by hypoxia. Soc. Neurosci. Abstr. 17: 118.Google Scholar
  16. Storm, D.R., Hansel, C., Hacker, B., Parent, A., and Linden, D.J., 1998, Impaired cerebellar long-term potentiation in type I adenylyl cyclase mutant mice. Neuron 20(6): 1199–1210.Google Scholar
  17. Wang, Z.-Z., He, L., Stensaas, L.J., Dinger, B.G., and Fidone, S.J., 1991, Localization and in vitro actions of atrial natriuretic peptide in the cat carotid body. J. Appl. Physiol. 70(2): 942–946.Google Scholar
  18. Zhang, X.-Q., Pang, L., and Eyzaguirre, C., 1995, Effects of hypoxia on the intracellular K+ of clustered and isolated glomus cells of mice and rats. Brain Res. 676: 413–420.Google Scholar
  19. Zhou, L., Zhang, C.L., Messing, A., and Chiu, S.Y., 1998, Temperature-sensitive neuromuscular transmission in Kv1.1 null mice: role of potassium channels under the myelin sheath in young nerves. J. Neurosci. 18(18): 7200–7215.Google Scholar
  20. Zimmer, A., Zimmer, A.M., Baffi, J., Usdin, T., Reynolds, K., Konig, M., Palkovits, M., and Mezey, E., 1998, Hypoalgesia in mice with a targeted deletion of the tachykinin 1 gene. Proc. Natl. Acad. Sci. USA 95(5): 2630–2635.Google Scholar

Copyright information

© Kluwer Academic Publishers 2002

Authors and Affiliations

  • L. He
    • 1
  • J. Chen
    • 1
  • B. Dinger
    • 1
  • S. Fidone
    • 1
  1. 1.Department of PhysiologyUniversity of Utah School of MedicineSalt Lake City

Personalised recommendations