Abstract
Contamination of soil through heavy metals like As, Hg, Cd, Cr, Pb, etc. cause different environmental hazards, soil pollutions, and destruction of ecosystems integrity. Heavy metal exposure to plants causes severe oxidative stress due to production of free radical which leads to changes in morpho-physiological, biochemical, cellular, and tissue level gene integrity in entire plants. In these adverse conditions, crop plants develop several complex physiological, biochemical, and molecular adaptive mechanisms for better stability, tolerance, and survival. Plant scientists have used conventional breeding techniques for development of agriculturally important heavy metal stress tolerant cultivars which are time consuming and labor intensive. Recent advances in various branches of biological sciences such as hormonal interactions, microbiological engineering, transcriptomics, proteomics, metabolomics, and ionomics have dominantly supported the identification and characterization of genes, transcription factors, and stress tolerance proteins involved in heavy metal detoxifications, which apparently helps in developing metal stress tolerant crop cultivars. This book chapter summarizes several tolerance mechanisms of plants under heavy metal toxicity, the knowledge of recent advances on the role of hormones, microbes, genetic engineering, metabolomics, ionomics (trace elements), proteomics (stress related proteins), and various signal transduction pathways in relation to various heavy metals.
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References
Abbas G, Murtaza B, Bibi I, Shahid M, Niazi NK, Khan MI, Amjad M, Hussain M, Natasha (2018) Arsenic uptake, toxicity, detoxification, and speciation in plants: physiological, biochemical, and molecular aspects. Int J Environ Res Public Health 15(1):59
Adediran GA, Ngwenya BT, Mosselmans JFW, Heal KV, Harvie BA (2015) Mechanism behind bacteria induced plant growth promotion and Zn accumulation in Brassica juncea. J Hazard Mater 283:490–499. https://doi.org/10.1016/j.jhazmat.2014.09.064
Ahn YO, Kim SH, Lee J, Kim HR, Lee HS, Kwak SS (2012) Three Brassica rapa metallothionein genes are differentially regulated under various stress conditions. Mol Biol Rep 39(3):2059–2067
Ahsan N, Lee DG, Alam I, Kim PJ, Lee JJ, Ahn YO, Kwak SS, Lee IJ, Bahk JD, Kang KY, Renaut J, Komatsu S, Lee BH (2008) Comparative proteomic study of arsenic-induced differentially expressed proteins in rice roots reveals glutathione plays a central role during As stress. Proteomics 8:3561–3576
Akbulut M, Cakır S (2010) The effects of se phytotoxicity on the antioxidant systems of leaf tissues in barley (Hordeum vulgare L.) seedlings. Plant Physiol Biochem 48:160–166. https://doi.org/10.1016/j.plaphy.2009.11.001
Ali B, Xu X, Gill RA, Yang S, Ali S, Tahir M (2014) Promotive role of 5-aminolevulinic acid on mineral nutrients and antioxidative defense system under lead toxicity in Brassica napus. Ind Crop Prod 52:617–626
Anawar HM, García-Sánchez A, Hossain ZM (2013) In: Gupta DK (ed) Biogeochemical cycling of arsenic in soil–plant continuum: perspectives for phytoremediation. Heavy metal stress in plants. Springer, Berlin, pp 203–224. https://doi.org/10.1007/978-3-642-38469-1-11
Arenhart RA, De Lima JC, Pedron M, Carvalho FEL, Da Silveira JAG, Rosa SB (2013) Involvement of ASR genes in aluminium tolerance mechanisms in rice. Plant Cell Environ 36:52–67
Ashraf U, Kanu AS, Mo ZW, Hussain S, Anjum SA, Khan I (2015) Lead toxicity in rice; effects, mechanisms and mitigation strategies—a mini review. Environ Sci Pollut Res 22:18318–18332. https://doi.org/10.1007/s11356-015-5463-x
Atici O, Agar G, Battal P (2005) Changes in phytohormones contents in chickpea seeds germinating under lead or zinc stress. Biol Plant 49:215–222
Azcón R, Perálvarez MDC, Roldán A, Barea JM (2010) Arbuscular mycorrhizal fungi, Bacillus cereus, and Candida parapsilosis from a multi contaminated soil alleviate metal toxicity in plants. Microb Ecol 59:668–677
Azevedo R, Rodriguez E (2012) Phytotoxicity of mercury in plants: a review. J Bot 2012:848614. https://doi.org/10.1155/2012/848614
Babu AG, Kim JD, Oh BT (2013) Enhancement of heavy metal phytoremediation by Alnus firma with endophytic Bacillus thuringiensis GDB1. J Hazard Mater 250:477–483. https://doi.org/10.1016/j.jhazmat.2013.02.014
Babu AG, Shea PJ, Sudhakar D, Jung IB, Oh BT (2015) Potential use of Pseudomonas koreensis AGB-1 in associated with Miscanthus sinensis to remediate heavy metal (loid)-contaminated mining site soil. J Environ Manage 151:160–166
Baccouch S, Chaoui A, El Ferjani E (1998) Nickel-induced oxidative damage and antioxidant response in Zea mays shoots. Plant Physiol Biochem 36:689–694
Baryla A, Carrier P, Franck F, Coulomb C, Sahut C (2001) Leaf chlorosis in oilseed rape plants (Brassica napus) grown on cadmium-polluted soil: causes and consequences for photosynthesis and growth. Planta 212:696–709
Belimov AA, Puhalsky IV, Safronova VI, Shaposhnikov AI, Vishnyakova MA, Semenova EV (2015) Role of plant genotype and soil conditions in symbiotic plant-microbe interactions for adaptation of plants to cadmium polluted soils. Water Air Soil Pollut 226:264. https://doi.org/10.1007/s11270-015-2537-9
BGS & DPHE (2001) Arsenic contamination of groundwater in Bangladesh (four volumes). BGS technical report WC/00/19, British Geological Survey, Keyworth
Bienert GP, Thorsen M, Schüssler MD (2008) A subgroup of plant aquaporins facilitate the bi-directional diffusion of As(OH)3 and Sb(OH)3 across membranes. BMC Plant Biol 6:26
Boddi B, Oravecz A, Lehoczki E (1995) Effect of cadmium on organization and photoreduction of protochlorphyllide in dark-grown leaves and etioplast inner membrane preparations of wheat. Photosynthetica 31:411–420
Boening DW (2000) Ecological effects, transport, and fate of mercury: a general review. Chemosphere 40(12):1335–1351
Boominathan R, Doran PM (2002) Ni-induced oxidative stress in roots of the Ni hyperaccumulator, Alyssum bertolonii. New Phytol 156:205–215
Castiglione S, Franchin C, Fossati T, Lingua G, Torrigiani P, Biondi S (2007) High zinc concentrations reduce rooting capacity and alter metallothionein gene expression in white poplar (Populus alba L. cv. Villafranca). Chemosphere 67(6):1117–1126
Castillo-Michel H, Hernandez-Viezcas J, Dokken KM, Marcus MA, Peralta-Videa JR, Gardea-Torresdey JL (2011) Localization and speciation of arsenic in soil and desert plant Parkinsonia florida using mu XRF and mu XANES. Environ Sci Technol 45:7848–7785
Charfeddine M, Charfeddine S, Bouaziz D, Messaoud RB, Bouzid RG (2017) The effect of cadmium on transgenic potato (Solanum tuberosum) plants overexpressing the StDREB transcription factors. Plant Cell Tiss Org Cult 128(3):521–541
Chatterjee J, Chatterjee C (2000) Phytotoxicity of cobalt, chromium and copper in cauliflower. Environ Pollut 109:69–74
Chatterjee C, Dube BK, Sinha P, Srivastava P (2004) Detrimental effects of lead phytotoxicity on growth, yield, and metabolism of rice. Commun Soil Sci Plant Anal 35:255–265. https://doi.org/10.1081/CSS-120027648
Chen YA, Chi WC, Huang TL, Lin CY, Quynh Nguyeh TT, Hsuing YC (2012) Mercury-induced biochemical and proteomic changes in rice roots. Plant Physiol Biochem 55:23–32. https://doi.org/10.1016/j.plaphy.2012.03.008
Chen L, Luo SL, Li XJ, Wan Y, Chen JL, Liu CB (2014) Interaction of Cd-hyperaccumulator Solanum nigrum L. and functional endophyte Pseudomonas sp. Lk9 on soil heavy metals uptake. Soil Biol Biochem 68:300–308. https://doi.org/10.1016/j.soilbio.2013.10.021
Chen Y, Wang S, Nan Z, Ma J, Zang F (2017) Effect of fluoride and cadmium stress on the uptake and translocation of fluoride and cadmium and other mineral nutrition elements in radish in single element or co-taminated sierozem. Environ Exp Bot 134:54–61
Chiang HC, Lo JC, Yeh KC (2006) Genes associated with heavy metal tolerance and accumulation in Zn/Cd hyperaccumulator Arabidopsis halleri: a genomic survey with cDNA microarray. Environ Sci Technol 40(21):6792–6798
Choudhary SP, Kanwar M, Bhardwaj R, Yu JQ, Tran LS (2012) Chromium stress mitigation by polyamine-brassinosteroid application involves phytohormonal and physiological strategies in Raphanus sativus L. PLoS One 7:e33210
Clemens S, Palmgreen MG, Kramer U (2002) A long way ahead: understanding and engineering plant metal accumulation. Trends Plant Sci 7:309–315
Dalcorso G, Farinati S, Furini A (2010) Regulatory networks of cadmium stress in plants. Plant Signal Behav 5(6):1–5
Dar TA, Moin U, Khan MMA, Hakeem KR, Jaleel H (2015) Jasmonates counter plant stress: a review. Environ Exp Bot 115:49–57
Das N, Bhattacharya S, Maiti MK (2016) Enhanced cadmium accumulation and tolerance in transgenic tobacco overexpressing rice metal tolerance protein gene OsMTP1 is promising for phytoremediation. Plant Physiol Biochem 105:297–309
De Araújo RP, de Almeida AAF, Pereira LS, Mangabeira PA, Souza JO (2017) Photosynthetic, antioxidative, molecular and ultrastructural responses of young cacao plants to Cd toxicity in the soil. Ecotoxicol Environ Saf 144:148–157
Delnomdedieu M, Basti MM, Otvos JD, Thomas DJ (1994) Reduction and binding of arsenate and dimethyl arsenate by glutathione a magnetic resonance study. Chem Biol Interact 90:139–155
Dimkpa CO, Svatoš A, Dabrowska P, Schmidt A, Boland W, Kothe E (2008) Involvement of siderophores in the reduction of metal-induced inhibition of auxin synthesis in Streptomyces spp. Chemosphere 74:19–25. https://doi.org/10.1016/j.chemosphere.2008.09.079
Dumont E, Vanhaecke F, Cornelis R (2006) Selenium speciation from food source to metabolites: a critical review. Anal Bioanal Chem 385:1304–1323. https://doi.org/10.1007/s00216-006-0529-8
Faè M, Balestrazzi A, Confalonieri M, Donà M, Macovei A, Valassi A, Carbonera D (2014) Copper-mediated genotoxic stress is attenuated by the overexpression of the DNA repair gene MtTdp2α (tyrosyl-DNA phosphodiesterase 2) in Medicago truncatula plants. Plant Cell Rep 33(7):1071–1080
Feng J, Wang Y, Zha J, Zhu L, Bian X, Zhang W (2011) Source attributions of heavy metals in rice plant along highway in eastern China. J Environ Sci 23:1158–1164. https://doi.org/10.1016/S1001-0742(10)60529-3
Flathman PE, Lanza GR (1998) Phytoremediation: current views on an emerging green technology. J Soil Contam 7:415–432
Flora SJS (2009) Structural, chemical and biological aspects of antioxidants for strategies against metal and metalloid exposure. Oxid Med Cell Longev 2:191–206
Gajewska E, Wielanek M, Bergier K, Skłodowska M (2009) Nickel induced depression of nitrogen assimilation in wheat roots. Acta Physiol Plant 31:1291–1300
Gangwar S, Singh VP, Srivastava PK, Maurya JN (2011) Modification of chromium (VI) phytotoxicty by exogenous gibberellic acid application in Pisum sativa (L.) seedlings. Acta Physiol Plant 33:1385–1397
Gao Y, Miao C, Mao L, Zhou P, Jin Z (2010) Improvement of phytoextraction and antioxidative defense in Solanum nigrum L. under cadmium stress by application of cadmium-resistant strain and citric acid. J Hazard Mater 181:771–777
Garg N, Aggarwal N (2012) Effect of mycorrhizal inoculations on heavy metal uptake and stress alleviation of Cajanus cajan (L.) Millsp. Genotypes grown in cadmium and lead contaminated soils. Plant Growth Regul 66:9–26
Gielen H, Vangronsveld J, Cuypers A (2017) Cd-induced Cu deficiency responses in Arabidopsis thaliana: are phytochelatins involved? Plant Cell Environ 40:390–400
Gong B, Nie W, Yan Y, Gao Z, Shi Q (2017) Unravelling cadmium toxicity and nitric oxide induced tolerance in Cucumis sativus: insight into regulatory mechanisms using proteomics. J Hazard Mater 336:202–213
Gontia-Mishra I, Sapre S, Sharma A, Tiwari S (2016) Alleviation of mercury toxicity in wheat by the interaction of mercury-tolerant plant growth promoting rhizobacteria. J Plant Growth Regul 35:1000–1012. https://doi.org/10.1007/s00344-016-9598-x
Gonzales-Chavez MC, Carrillo-Gonzales R, Wright SF, Nichols KA (2004) The role of glomalin, a protein produced by arbuscular mycorrhizal fungi, in sequestering potentially toxic elements. Environ Pollut 130:317–323. https://doi.org/10.1016/j.envpol.2004.01.004
Grill E, Loffler S, Winnacke EL, Zenk MH (1989) Phytochelatins, the heavy-metal-binding peptides of plants, are synthesized from glutathione by a specific γ-glutamylcysteine dipeptidyl transpeptidase (phytochelatin synthase). Proc Natl Acad Sci USA 86(18):6838–6842
Guan Z, Chai T, Zhang Y, Xu J, Wei W (2009) Enhancement of Cd tolerance in transgenic tobacco plants overexpressing a Cd-induced catalase cDNA. Chemosphere 76:623–630. https://doi.org/10.1016/j.chemosphere.2009.04.047
Gumaelius L, Lahner B, Salt DE, Banks JA (2004) Arsenic hyperaccumulation in gametophytes of Pteris vittata. A new model system for analysis of arsenic hyperaccumulation. Plant Physiol 136:3198–3208
Han FX, Su YDL, Monts MJ, Plodine C, Banin A, Triplett GE (2003) Assessment of global industrial-age anthropogenic arsenic contamination. Naturwissenschaften 90(9):395–401
Hansda A, Kumar V (2017) Cu-resistant Kocuria sp. CRB15: a potential PGPR isolated from the dry tailing of Rakha copper mine. 3 Biotech 7:132. https://doi.org/10.1007/s13205-017-0757-y
Hassan TU, Bano A, Naz I (2017) Alleviation of heavy metals toxicity by the application of plant growth promoting rhizobacteria and effects on wheat grown in saline sodic field. Int J Phytoremediation 19:522–529. https://doi.org/10.1080/15226514.2016.1267696
He H, Ye Z, Yang D, Yan J, Xiao L, Zhong T, Yuan M, Cai X, Fang Z, Jing Y (2013) Characterization of endophytic Rahnella sp. JN6 from Polygonum pubescens and its potential in promoting growth and Cd, Pb, Zn uptake by Brassica napus. Chemosphere 90:1960–1965
Hossain Z, Komatsu S (2013) Contribution of proteomic studies towards understanding plant heavy metals stress response. Front Plant Sci 3:310. https://doi.org/10.3389/fpls.2012.00310
Hossain MA, Hossain MD, Rohman MM, da Silva JAT, Fujita M (2012) Onion major compounds (flavonoids, organosulfurs) and highly expressed glutathione-related enzymes: possible physiological interaction, gene cloning and abiotic stress response. In: Aguirre CB, Jaramillo LM (eds) Onion consumption and health. Nova Science, New York
Iuchi S, Koyama H, Iuchi A, Kobayashi Y, Kitabayashi S, Kobayashi Y (2007) Zinc finger protein STOP1 is critical for proton tolerance in Arabidopsis and coregulates a key gene in aluminum tolerance. Proc Natl Acad Sci U S A 104:9900–9905. https://doi.org/10.1073/pnas.0700117104
Jain CK, Ali I (2000) Arsenic: occurrence, toxicity and speciation techniques. Water Res 34:4304–4312
Jaiswal S (2011) Role of rhizobacteria in reduction of arsenic uptake, by plants: a review. J Bioremed Biodegr 2:126
Jarvis C, Jones LHP, Hopper MJ (1976) Cadmium uptake from solution by plants and its transport from roots to shoots. Plant Soil 44:179–191
Jonak C, Nakagami H, Hirt H (2004) Heavy metal stress. Activation of distinct mitogen-activated protein kinase pathways by copper and cadmium. Plant Physiol 136(2):3276–3283
Kanwar MK, Bhardwaj R, Arora P, Chowdhary SP, Sharma P, Kumar S (2012) Plant steroid hormones produced under Ni stress are involved in the regulation of metal uptake and oxidative stress in Brassica juncea L. Chemosphere 86:41–49
Khan MIR, Khan NA (2014) Ethylene reverses photosynthetic inhibition by nickel and zinc in mustard through changes in PS II activity, photosynthetic nitrogen use efficiency, and antioxidant metabolism. Protoplasma 251:1007–1019
Khan I, Ahmad A, Iqbal M (2009) Modulation of antioxidant defence system for arsenic detoxification in Indian mustard. Ecotoxicol Environ Saf 72:626–634
Kim T, Balish RS, Heaton AC, McKinney EC, Dhankher OP, Meagher RB (2005) Engineering a root specific, repressor-operator gene complex. Plant Biotechnol J 3:571–582
Koch I, Wang L, Ollson CA, Cullen WR, Reimer KJ (2000) The predominance of inorganic arsenic species in plants from yellow knife, Northwest Territories, Canada. Environ Sci Technol 34(1):22–26
Kopittke PM, de Jonge MD, Wang P, McKenna BA, Lombi E, Paterson DJ, Howard DL, James SA (2013) Laterally resolved speciation of arsenic in roots of wheat and rice using fluorescence-XANES imaging. New Phytol 201:1251–1262
Koprivova A, North KA, Kopriva S (2008) Complex signalling network in regulation of adenosine-5′-phosphosulphate reductase by salt stress in Arabidopsis roots. Plant Physiol 146:1408–1420
Łabanowska M, Filek M, Koscielniak J, Kurdziel M, Kulis E, Hartikainen H (2012) The effects of short-term selenium stress on Polish and Finnish wheat seedlings-EPR, enzymatic and fluorescence studies. J Plant Physiol 169:275–284. https://doi.org/10.1016/j.jplph.2011.10.012
Larsson EH, Bornman JF, Asp H (1998) Influence of UV-B radiation and Cd2+ on chlorophyll fluorescence, growth and nutrient content in Brassica napus. J Exp Bot 49:1031–1039
Lee K, Bae DW, Kim SH (2010) Comparative proteomic analysis of the short-term responses of rice roots and leaves to cadmium. J Plant Physiol 167(3):161–168
Lehotai N, Kolbert Z, Peto A, Feigl G, Ördög A, Kumar D (2012) Selenite-induced hormonal and signaling mechanisms during root growth of Arabidopsis thaliana L. J Exp Bot 63:5677–5687
Lequeux H, Hermans C, Lutts S, Verbruggen N (2010) Response to copper excess in Arabidopsis thaliana: impact on the root system architecture, hormone distribution, lignin accumulation and mineral profile. Plant Physiol Biochem 48:673–682
Liu J, Leng X, Wang M, Zhu Z, Dai Q (2011) Iron plaque formation on roots of different rice cultivars and the relation with lead uptake. Ecotoxicol Environ Saf 74:1304–1309. https://doi.org/10.1016/j.ecoenv.2011.01.017
Luo S, Xu T, Chen L, Chen J, Rao C, Xiao X, Wan Y, Zeng G, Long F, Liu C, Liu Y (2012) Endophyte-assisted promotion of biomass production and metal uptake of energy crop sweet sorghum by plant-growth-promoting endophyte Bacillus sp. SLS18. Appl Microbiol Biotechnol 93:1745–1753
Luo ZB, He J, Polle A, Rennenberg H (2016) Heavy metal accumulation and signal transduction in herbaceous and woody plants: paving the way for enhancing phytoremediation efficiency. Biotechnol Adv 34:1131–1148
Ma Y, Prasad MNV, Rajkumar M, Freitas H (2011) Plant growth promoting rhizobacteria and endophytes accelerate phytoremediation of metalliferous soils. Biotechnol Adv 29:248–258. https://doi.org/10.1016/j.biotechadv.2010.12.001
Ma Y, Rajkumar M, Luo Y, Freitas H (2013) Phytoextraction of heavy metal polluted soils using Sedum plumbizincicola inoculated with metal mobilizing Phyllobacterium myrsinacearum RC6b. Chemosphere 93:1386–1392
Ma Y, Oliveira RS, Nai FJ, Rajkumar M, Luo YM, Rocha I, Freitas H (2015) The hyperaccumulator Sedum Plumbizincicola harbors metal-resistant endophytic bacteria that improve its phytoextraction capacity in multi-metal contaminated soil. J Environ Manage 156:62–69. https://doi.org/10.1016/j.jenvman.2015.03.024
Magdziak Z, Kozlowska M, Kaczmarek Z, Mleczek M, Chadzinikolau T, Drzewiecka K (2011) Influence of Ca/Mg ratio on phytoextraction properties of Salix viminalis II. Secretion of low molecular weight organic acids to the rhizosphere. Ecotoxicol Environ Saf 74:33–40. https://doi.org/10.1007/s00468-012-0821-5
Marschner H (1995) Mineral nutrition of higher plants, 2nd edn. Academic Press, London, p 889
Masood A, Iqbal N, Khan NA (2012) Role of ethylene in alleviation of cadmium-induced photosynthetic capacity inhibition by sulphur in mustard. Plant Cell Environ 35:524–533
Mayerová M, Petrová Š, Madaras M, Lipavský J, Šimon T (2017) No enhanced phytoextraction of cadmium, zinc, and lead by high yielding crops. Environ Sci Pollut Res 24:14706–14716
McLaughlin MJ, Tiller KG, Naidu R, Stevens DP (1996) Reviewed: the behaviour and impact of contaminants in fertilizers. Aust J Soil Res 34:1–54
Meng H, Hua S, Shamsi IH, Jilani G, Li Y, Jiang L (2009) Cadmium- induced stress on the seed germination and seedling growth of Brassica napus and its alleviation through exogenous plant growth regulators. Plant Growth Regul 58:47–59
Miransari M (2011) Arbuscular mycorrhizal fungi and nitrogen uptake. Arch Microbiol 193:77–81
Mishra A, Choudhary MA (1998) Amelioration of lead and mercury effects on germination and rice seedling growth by antioxidants. Biol Plantarum 41:469–473
Mittler R (2002) Oxidative stress, antioxidant and stress tolerance. Trends Plant Sci 7:841–851. https://doi.org/10.1016/S1360-1385(02)02312-9
Mohan D, Pittman CU (2006) Activated carbons and low cost adsorbents for remediation of tri-and hexavalent chromium from water. J Hazard Mater 137:762–811
Mohan TC, Castrillo G, Navarro C, Zarco-Fernandez S, Ramireddy E, Mateo C, Zanarreno AM, Paz-Ares J, Munoz R, Garcia-Mina JM, Hernandez LE, Schmulling T, Leyva A (2016) Cytokinin determines thiol-mediated arsenic tolerance and accumulation. Plant Physiol 171:1418–1426
Mortel VD, Villanueva JE, Schat LA, Kwekkeboom H, Coughlan J, Moerland S (2006) Large expression differences in genes for iron and zinc homeostasis, stress response, and lignin biosynthesis distinguish roots of Arabidopsis thaliana and the related metal hyperaccumulator Thlaspi caerulescens. Plant Physiol 142:1127–1134. https://doi.org/10.1104/pp.106.082073
Mosa KA, Ismail A, Helmy M (2017) Functional genomics combined with other omics approaches for better understanding abiotic stress tolerance in plants. In: Sunkar R (ed) Plant stress tolerance. Springer International, Cham, pp 55–73
Mroczek-Zdyrska M, Wójcik M (2012) The influence of selenium on root growth and oxidative stress induced by lead in Vicia faba L. minor plants. Biol Trace Elem Res 147:320–328. https://doi.org/10.1007/s12011-011-9292-6
Mukhopadhyay A, Vij S, Tyagi AK (2004) Overexpression of a zinc finger protein gene from rice confers tolerance to cold, dehydration, and salt stress in transgenic tobacco. Proc Natl Acad Sci U S A 101:6309–6314. https://doi.org/10.1073/pnas.0401572101
Nagajyoti PC, Lee KD, Sreekanth TVM (2010) Heavy metals, occurrence and toxicity for plants: a review. Environ Chem Lett 8:199–216
Oliveira H (2012) Chromium as an environmental pollutant: insights on induced plant toxicity. J Bot 37:1–8
Opdenakker K, Remans T, Keunen E, Vangronsveld J, Cuypers A (2012) Exposure of Arabidopsis thaliana to Cd or Cu excess leads to oxidative stress mediated alterations in MAPKinase transcript levels. Environ Exp Bot 83:53–61. https://doi.org/10.1016/j.envexpbot.2012.04.003
Ortega-Villasante C, Rellán-Álvarez R, Del Campo FF, Carpena-Ruiz RO, Hernández LE (2005) Cellular damage induced by cadmium and mercury in Medicago sativa. J Exp Bot 56:2239–2251. https://doi.org/10.1093/jxb/eri223
Palmieri L, Picault N, Arrigoni R, Besin E, Palmieri F, Hodges M (2008) Molecular identification of three Arabidopsis thaliana mitochondrial dicarboxylate carrier isoforms: organ distribution, bacterial expression, reconstitution into liposomes and functional characterization. Biochem J 410:621–629
Panday N, Sharma CP (2002) Effect of heavy metals Co2+, Ni2+, and Cd2+ on growth and metabolism of cabbage. Plant Sci 163:753–758
Pandey S, Ghosh PK, Ghosh S, De TK, Maiti TK (2013) Role of heavy metal resistant Ochrobactrum sp. and Bacillus sp. strains in bioremediation of a rice cultivar and their PGPR like activities. J Microbiol 51:11–17. https://doi.org/10.1007/s12275-013-2330-7
Patra M, Sharma A (2000) Mercury toxicity in plants. Bot Rev 66(3):379–422
Patra M, Bhowmik N, Bandopadhyay B, Sharma A (2004) Comparison of mercury, lead and arsenic with respect to genotoxic effects on plant systems and the development of genetic tolerance. Environ Exp Bot 52(3):199–223
Pietrini F, Iannelli MA, Pasqualini S, Massacci A (2003) Interaction of cadmium with glutathione and photosynthesis in developing leaves and chloroplasts of Phragmites australis (Cav.) Trin. ex Steudel. Plant Physiol 133:829–837
Pilon-Smits E (2005) Phytoremediation. Annu Rev Plant Biol 56:15–39
Pourrut B, Shahid M, Camille D, Peter W, Eric P (2011) Lead uptake, toxicity, and detoxification in plants. Rev Environ Contam Toxicol 213:113–136. https://doi.org/10.1007/978-1-4419-9860-6_4
Raab A, Wright SH, Jaspars M, Meharg AA, Feldmann J (2007) Penta valent arsenic can bind to biomolecules. Angew Chem Int Ed Engl 46:2594–2597
Rajkumar M, Sandhya S, Prasad MNV, Freitas H (2012) Perspectives of plant-associated microbes in heavy metal phytoremediation. Biotechnol Adv 30:1562–1574. https://doi.org/10.1016/j.biotechadv.2012.04.011
Ramos J, Clemente MR, Naya L, Loscos J, Rontome C, Sato S (2007) Phytochelatin synthases of the model legume Lotus japonicas. A small multigene family with different responses to cadmium and alternative lyspiced variants. Plant Physiol 143:110–118
Rao KVM, Sresty TVS (2004) Antioxidative parameters in the seedlings of pigeonpea (Cajanus cajan (L.) Millspaugh) in response to Zn and Ni stresses. Plant Sci 157:113–118
Ruiz ON, Alvarez D, Torres C, Roman L, Daniell H (2011) Metallothionein expression in chloroplasts enhances mercury accumulation and phytoremediation capability. Plant Biotechnol J 9:609–617. https://doi.org/10.1111/j.1467-7652.2011.00616.x
Sarry JE, Kuhn L, Ducruix C (2006) The early responses of Arabidopsis thaliana cells to cadmium exposure explored by protein and metabolite profiling analyses. Proteomics 6(7):2180–2198
Schiavon M, Moro I, PilonSmits EA, Matozzo V, Malagoli M, DallaVecchia F (2012) Accumulation of selenium in Ulva sp. and effects on morphology, ultrastructure and antioxidant enzymes and metabolites. Aquat Toxicol 123:222–231
Schützendübel A, Polle A (2002) Plant responses to abiotic stress : heavy metal-induced oxidative stress and protection by mycorrization. J Exp Bot 53:1351–1365
Shahid M, Pinelli E, Dumat C (2012) Review of Pb availability and toxicity to plants in relation with metal speciation; role of synthetic and natural organic ligands. J Hazard Mater 219–220:1–12. https://doi.org/10.1016/j.jhazmat.2012.01.060
Shahzad Z, Gosti F, Frerot H, Lacombe E, Roosens N, Saumitou Laprade P (2010) The five AhMTP1 zinc transporters undergo different evolutionary fates towards adaptive evolution to zinc tolerance in Arabidopsis halleri. PLoS Genet 6:e1000911. https://doi.org/10.1371/journal.pgen.1000911
Shanker AK (2005) Chromium toxicity in plants. Environ Int 31:739–753
Sharaf AEMM, Farghal II, Sofy MR (2009) Role of gibberellic acid in abolishing the detrimental effects of cadmium and lead on the broad bean and lupin plants. Res J Agric Biol Sci 5:668–673
Sharma SS, Dietz KJ (2006) The significance of amino acids and amino acid-derived molecules in plant responses and adaptation to heavy metal stress. J Exp Bot 57:711–726
Sharma SS, Dietz KJ (2009) The relationship between metal toxicity and cellular redox imbalance. Trends Plant Sci 14(1):43–50
Sharma DC, Sharma CP (1996) Chromium uptake and toxicity effects on growth and metabolic activities in wheat, Triticum aestivum L. cv. UP 2003. Indian J Exp Biol 34:689–691
Shaw BP, Sahu SK, Mishra RK (2004) Heavy metal induced oxidative damage in terrestrial plants. In: Prasad MNV (ed) Heavy metal stress in plants: from biomolecules to ecosystems. Narosa Publishing House, New Delhi, pp 84–126
Shi WG, Li H, Liu TX, Polle A, Peng CH, Luo ZB (2015) Exogenous abscisic acid alleviates zinc uptake and accumulation in Populus × canescens exposed to excess zinc. Plant Cell Environ 38:207–223
Shin H, Shin HS, Gary R, Harrison MJ (2004) Phosphate transport in Arabidopsis: Pht1;1 and Pht1;4 play a major role in phosphate acquisition from both low- and high-phosphate environments. Plant J 39:629–642
Shin M, Shim J, You Y, Myung H, Bang KS, Cho M (2012) Characterization of lead resistant endophytic Bacillus sp. MN3-4 and its potential for promoting lead accumulation in metal hyperaccumulator Alnus firma. J Hazard Mater 19:314–320. https://doi.org/10.1016/j.jhazmat.2011.11.010
Singh N, Ma LQ, Srivastava M, Rathinasabapathi B (2006) Metabolic adaptations to arsenic induced oxidative stress in Pteris vittata L. and Pterisensi formis L. Plant Sci 170:274–282
Singh HP, Mahajan P, Kaur S, Batish DR, Kohli RK (2013) Chromium toxicity and tolerance in plants. Environ Chem Lett 11:229–254
Singh S, Barla A, Srivastava A, Bose S (2015) Isolation of arsenic resistant bacteria from Bengal Delta sediments and their efficiency in arsenic removal from soil in association with Pteris vittata. Geomicrobiol J 32(8):712–723
Singh S, Parihar P, Singh R, Singh VP, Prasad SM (2016) Heavy metal tolerance in plants: role of transcriptomics, proteomics, metabolomics, and ionomics. Front Plant Sci 6:1143. https://doi.org/10.3389/fpls.2015.01143
Sirhindi G, Mir MA, Sharma P, Singh GS, Kaur H, Mushtaq R (2015) Modulatory role of jasmonic acid on photosynthesis pigments, antioxidants and stress makers of Glycine max L. under nickel stress. Physiol Mol Biol Plants 21:559–565
Song WY, Yamaki T, Yamaji N, Ko D, Jung KH, Fujii-Kashino M (2014) A rice ABC transporter, OsABCC1, reduces arsenic accumulation in the grain. PNAS 111:15699–15704. https://doi.org/10.1073/pnas.1414968111
Sors TG, Ellis DR, Na GN, Lahner B, Lee S, Leustek T (2005) Analysis of sulfur and selenium assimilation in Astragalus plants with varying capacities to accumulate selenium. Plant J 42:785–797. https://doi.org/10.1111/j.1365-313X.2005.02413.x
Srivastava S, Shanker K, Srivatava R, Srivastava S, Dass S, Prakash S, Srivastava MM (1998) Effect of selenium supplementation on the uptake and translocation of chromium in spinach (Spinacea oleracea). Bull Environ Contam Toxicol 60:750–758
Srivastava AK, Venkatachalam P, Raghothama KG, Sahi SV (2007) Identification of lead-regulated genes by suppression subtractive hybridization in the heavy metal accumulator Sesbania drummondii. Planta 225:1353–1365
Srivastava S, Suprasanna P, D’Souza SF (2011) Redox states and energetic equilibrium determine the magnitude of stress in Hydrilla verticillata upon exposure to arsenate. Protoplasma 248:805–816
Srivastava S, Srivastava AK, Suprasanna P, D’Souza SF (2013a) Identification and profiling of arsenic stress induced microRNA in Brassica juncea. J Exp Bot 64:303–315
Srivastava S, Verma PC, Chaudhary V, Singh N, Abhilash PC, Kumar KV (2013b) Inoculation of arsenic-resistant Staphylococcus arlettae on growth and arsenic uptake in Brassica juncea (L.) Czern. var. R-46. J Hazard Mater 262:1039–1047. https://doi.org/10.1016/j.jhazmat.2012.08.019
Sun WJ, Sierra-Alvarez R, Milner L, Field JA (2010) Anoxic oxidation of arsenite linked to chlorate reduction. Appl Environ Microbiol 76:6804–6811
Sun SK, Chen Y, Che J, Konishi N, Tang Z, Miller AJ, Ma JF, Zhao FJ (2018) Decreasing arsenic accumulation in rice by overexpressing OsNIP1;1 and OsNIP3;3 through disrupting arsenite radial transport in roots. New Phytol 219(2):641–653. https://doi.org/10.1111/nph.15190
Tamaoki M, Freeman JL, Pilon-Smits EAH (2008) Cooperative ethylene and jasmonic acid signaling regulates selenate resistance in Arabidopsis. Plant Physiol 146:1219–1230. https://doi.org/10.1104/pp.107.110742
Tang W, Charles TM, Newton RJ (2005) Overexpression of the pepper transcription factor CaPF1 in transgenic Virginia pine (Pinus Virginiana Mill.) confers multiple stress tolerance and enhances organ growth. Plant Mol Biol 59:603–617
Tchounwou PB, Yedjou CG, Patlolla AK, Sutton DJ (2012) Heavy metals toxicity and the environment. EXS 101:133–164
Thomas JC, Perron M, LaRosa PC, Smigocki AC (2005) Cytokinin and the regulation of a tobacco metallothionein-like gene during copper stress. Physiol Plant 123:262–271
Tu C, Ma LQ (2003) Interactive effects of pH, arsenic and phosphorus on uptake of As and P and growth of the arsenic hyperaccumulator Pteris vittata L. under hydroponic conditions. Environ Exp Bot 50:243–251
Uroz S, Calvaruso C, Turpault MP, Sarniguet A, deBoer W, Leveau JHJ (2009) Efficient mineral weathering is a distinctive functional trait of the bacterial genus Collimonas. Soil Biol Biochem 41:2178–2186. https://doi.org/10.1016/j.soilbio.2009.07.031
Vassilev A, Lidon F, Scotti P, Da Graca M, Yordanov I (2004) Cadmium-induced changes in chloroplast lipids and photosystem activities in barley plants. Biol Plant 48:153–156
Vázquez S, Esteban E, Carpena RO (2008) Evolution of arsenate toxicity in nodulated white lupine in a long-term culture. J Agric Food Chem 56:8580–8587
Villiers F, Ducruix C, Hugouvieux V, Jarno N, Ezan E, Garin J (2011) Investigating the plant response to cadmium exposure by proteomic and metabolomic approaches. Proteomics 11:1650–1663
Wagner GJ (1993) Accumulation of cadmium in crop plants and its consequences to human health. Adv Agron 51:173–212
Wang HH, Kang J, Zeng FH, Jiang MY (2001) Effect of nickel at high concentractions on growth activities of enzymes of rice seedlings. Acta Agron Sin 27:953–957
WHO (2009) Global health risks: mortality and burden of disease attributable to selected major risks. http://www.who.int/healthinfo/global_burden_disease/GlobalHealth2009:Risks_report_annex.pdf
Wilkinson S, Kudoyarova GR, Veselov DS, Arkhipova TN, Davies WJ (2012) Plant hormones interactions: innovative target for plant breeding and management. J Exp Bot 63:3499–3509
Wu XX, Chen JL, Xu S, Zhu ZW, Zha DS (2016) Exogenous 24- epibrasinosteroid alleviates zinc-induced toxicity in eggplant (Solanum melongena L.) seedlings by regulating the glutathione ascorbate- dependent detoxification pathway. J Hortic Sci Biotech 91:412–420
Xia Z, Sun K, Wang M, Wu K, Zhang H, Wu J (2012) Overexpression of a maize sulfite oxidase gene in tobacco enhances tolerance to sulfite stress via sulfite oxidation and CAT-mediated H2O2 scavenging. PLoS One 7:e37383. https://doi.org/10.1371/journal.pone.0037383
Xu XY, McGrath SP, Zhao FJ (2007) Rapid reduction of arsenate in the medium mediated by plant roots. New Phytol 176:590–599
Xu J, Wang W, Sun J (2011) Involvement of auxin and nitric oxide in plant Cd-stress responses. Plant and Soil 346(1):107–119
Yadav SK (2010) Heavy metals toxicity in plants: an overview on the role of glutathione and phytochelatins in heavy metal stress tolerance of plants. S Afr J Bot 76:167–179. https://doi.org/10.1016/j.sajb.2009.10.007
Yang X, Feng Y, He Z, Stoffell PJ (2005a) Molecular mechanisms of heavy metal hyper accumulation and phytoremediation. J Trace Elem Med Biol 18:339–353
Yang XE, Jin XF, Feng Y, Islam E (2005b) Molecular mechanisms and genetic basis of heavy metal tolerance/ hyperaccumulation in plants. J Integr Plant Biol 47(9):1025–1035
Yu L, Luo YF, Liao B, Xie LJ, Chen L, Xiao S, Li J, Hu S, Shu W (2012) Comparative transcriptomics analysis of transporters, phytohormone and lipid metabolism pathways in response to arsenic stress in rice (Oryza sativa). New Phytol 195:97–112
Yu C, Sun C, Shen C, Wang S, Liu F, Liu Y, Chen Y, Li C, Qian Q, Aryal B, Geisler M, Jiang de A, Qi Y (2015) The auxin transporter, OsAUX1, is involved in primary root and root hair elongation and in Cd stress responses in rice (Oryza sativa L.). Plant J 83:818–830
Yuan H, Huang X (2016) Inhibition of root meristem growth by cadmium involves nitric oxide-mediated repression of auxin accumulation and signalling in Arabidopsis. Plant Cell Environ 39:120–135
Yuan M, He H, Xiao L, Zhong T, Liu L, Li S, Deng P, Ye Z, Jing Y (2014) Enhancement of Cd phytoextraction by two Amaranthus species with endophytic Rahnella sp. JN27. Chemosphere 103:99–104
Yusuf M, Khan TA, Fariduddin Q (2016) Interaction of epibrassinolide and selenium ameliorates the excess copper in Brassica juncea through altered proline metabolism and antioxidants. Ecotoxicol Environ Saf 129:25–34
Zafar S, Aqil F, Ahmad I (2007) Metal tolerance and biosorption potential of filamentous fungi isolated from metal contaminated agricultural soil. Bioresour Technol 98:2557–2561. https://doi.org/10.1016/j.biortech.2006.09.051
Zhang W, Cai Y, Tu C, Ma LQ (2002) Arsenic speciation and distribution in an arsenic hyper accumulating plant. Sci Total Environ 300:167–177
Zhang F, Zhang H, Xia Y, Wang G, Xu L, Shen Z (2011) Exogenous application of salicylic acid alleviates Cd-toxicity and reduces hydrogen peroxide accumulation in root apoplasts of Phaseolus aureus and Vicia sativa. Plant Cell Rep 30:1475–1483
Zhao R, Zhao MX, Wang H, Taneiki Y, Zhang XR (2006) Arsenic speciation in moso bamboo shoot—a terrestrial plant that contains organoarsenic species. Sci Total Environ 37:293–303
Zhou ZS, Huang SQ, Guo K, Mehta SK, Zhang PC, Yang ZM (2007) Metabolic adaptations to mercury-induced oxidative stress in roots of Medicago sativa L. J Inorg Biochem 101:1–9. https://doi.org/10.1016/j.jinorgbio.2006.05.011
Zhou ZS, Wang SJ, Yang ZM (2008) Biological detection and analysis of mercury toxicity to alfalfa (Medicago sativa) plants. Chemosphere 70:1500–1509
Zhu YG, Pilon Smits EAH, Zhao FJ, Williams PN, Meharg AA (2009) Selenium in higher plants: understanding mechanisms for biofortification and phytoremediation. Trends Plant Sci 19:436–442. https://doi.org/10.1016/j.tplants.06.006
Zhu XF, Jiang T, Wang ZW, Lei GJ, Shi YZ, Li GX (2012) Gibberellic acid alleviates cadmium toxicity by reducing nitric oxide accumulation and expression of IRT1 in Arabidopsis thaliana. J Hazard Mater 240:302–307
Zou J, Wang G, Ji J, Wang J, Wu H (2017) Transcriptional, physiological and cytological analysis validated the roles of some key genes linked Cd stress in Salix matsudana Koidz. Environ Exp Bot 134:116–129
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Sarma, R.S., Prakash, P. (2020). Adverse Effect of Heavy Metal Toxicity in Plants’ Metabolic Systems and Biotechnological Approaches for Its Tolerance Mechanism. In: Rakshit, A., Singh, H., Singh, A., Singh, U., Fraceto, L. (eds) New Frontiers in Stress Management for Durable Agriculture. Springer, Singapore. https://doi.org/10.1007/978-981-15-1322-0_9
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