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Phytochemicals: New Avenues in Anticandidal Activity

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Recent Trends in Human and Animal Mycology

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Abstract

Human fungal infections have significantly increased in recent years particularly in immunocompromised hosts. Candidiasis is one of them. The emergence of new virulence factors and drug resistance in its aetiological agent Candida spp. beckons the need for new drug discoveries, as the present-day drugs are insufficient in combating the disease. Therapeutic alternatives can be the medicinal plants and phytocompounds, which have been in traditional system of medicine for their empirical antifungal properties. They could be reliable alternatives to overcome the disadvantages of antifungal drugs that include undesirable side effects, toxicity, recurrence, drug-drug interactions, and multiple drug resistance. The present article reviews the anticandidal activity of different medicinal plants and phytochemicals under the major classes of secondary metabolites such as phenolics, alkaloids, terpenoids, saponins, flavonoids, proteins, and peptides.

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Authors and Affiliations

  1. Department of Botany, Mahila Mahavidyalaya, Banaras Hindu University, Varanasi, India

    Richa Raghuwanshi

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Correspondence to Richa Raghuwanshi .

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  1. Department of Zoology, Mahila Mahavidyalaya, Banaras Hindu University, Varanasi, Uttar Pradesh, India

    Karuna Singh

  2. Department of Zoology, Mahila Mahavidyalaya, Banaras Hindu University, Varanasi, Uttar Pradesh, India

    Neelabh Srivastava

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Raghuwanshi, R. (2019). Phytochemicals: New Avenues in Anticandidal Activity. In: Singh, K., Srivastava, N. (eds) Recent Trends in Human and Animal Mycology. Springer, Singapore. https://doi.org/10.1007/978-981-13-9435-5_9

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