Fluoride Nanoparticles for Biomedical Applications

Pudovkin, M. S.; Rakhmatullin, R. M.

doi:10.1007/978-981-13-8954-2_5

M. S. Pudovkin² &
R. M. Rakhmatullin²

773 Accesses
5 Citations
1 Altmetric

Abstract

This chapter is devoted to the use of fluoride nanoparticles in biomedicine. We overview the use of the fluoride nanoparticles in important areas such as thermometry of a single cell, hyperthermia, photodynamic therapy, caries prevention, antioxidant therapy, magnetic resonance imaging, and bioimaging. The toxicity of some fluoride nanoparticles is also discussed. The main conclusion is that rare earth doped fluoride nanoparticles (especially rare earth doped LnF₃ (Ln = La, Ce), NaF₄, NaGdF₄) successfully proved its efficiency in the above-mentioned areas toward eukaryotic cells and small animals. It should be mentioned that LnF₃ (Ln = La, Ce) and NaGdF₄ nanoparticles demonstrate low toxicity in vitro and in vivo.

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Acknowledgments

The works was supported by the subsidy allocated to KFU for the state assignment in the sphere of scientific activities [3.1156.2017/4.6] and [3.5835.2017/6.7]. Maksim Pudovkin was supported by the research grant of Kazan Federal University.

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Kazan Federal University, Kazan, Russia
M. S. Pudovkin & R. M. Rakhmatullin

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M. S. Pudovkin
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Physics Department, Ewing Christian College, University of Allahabad, Allahabad, Uttar Pradesh, India
Ashutosh Kumar Shukla

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Pudovkin, M.S., Rakhmatullin, R.M. (2020). Fluoride Nanoparticles for Biomedical Applications. In: Shukla, A. (eds) Nanoparticles in Medicine. Springer, Singapore. https://doi.org/10.1007/978-981-13-8954-2_5

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DOI: https://doi.org/10.1007/978-981-13-8954-2_5
Published: 01 September 2019
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