Abstract
Optical biosensors are one of the most emerging devices due to high sensitivity and their compact size. In the past 10 years, optical biosensors based on interferometer and ring resonator structure can mostly be seen in the literature. During this decade, several biosensors families have been seen, which have advantageous combinations of properties. These lead to label-free biosensing, high quality factor and transmissivity, better limit of detection and sensitivity, cost-effective production, miniaturization, and the ability of lab on chip integration. This review paper compiles the most relevant research of the past years categorizing them into the group of interferometer-based biosensors and ring resonator based biosensors.
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Clark Lc, Lyons C (1962) Electrode systems for continuous monitoring in cardiovascular surgery. Ann NewYork Acad Sci 102:29–45
Oliver NS, Toumazou C, Cass AE, Johnston DG (2009) Glucose sensors: a review of current and emerging technology. Diabet Med 26:197–210
Fan X, White IM, Shopova SI, Zhu H, Suter JD, Sun Y (2008) Sensitive optical biosensors for unlabeled targets: A review. Anal Chim Acta 620(1–2):8–26
Sahu Sourabh, Ali Jalil, Singh Ghanshyam (2017) Refractive index biosensor using sidewall gratings in dual-slot waveguide. Opt Commun (Elsevier) 402:408–412
Sahu S, Jalil Ali, Singh G (2018) Optimization of dual-slot waveguide for refractive index biosensor. Optica Applicata (PSP) 48(1)
Sahu S, Kozadaev KV, Singh G (2016) Michelson interferometer based refractive index biosensor. In: Proceedings of 13th international conference on fiber optics and photonics, Photonic-16. IIT Kanpur, Dec 04–08, 2016, OSA Technical Digest, paper Th3A.60
Sahu S, Singh G (2016) Modeling of phase shift Bragg grating biosensor for non invasive detection of blood components. In: IEEE International Conference ICRAIE-2016, Jaipur, India, December 23–25
Sahu S, Singh G (2017) Modeling of grating slot waveguide for high-Q based refractive index sensor. In: IEEE International Conference COMPTELIX-2017, Jaipur, India, July 1–2
Schneider BH, Edwards JG, Hartman NF (1997) Hartman interferometer: versatile integrated optic sensor for label-free, real-time quantification of nucleic acids, proteins, and pathogens. Clin Chem 43:1757
Schneider BH, Dickinson EL, Vach MD, Hoijer JV, Howard LV (2000) Highly sensitive optical chip immunoassays in human serum. Biosens Bioelectron 15:13–22
De Vos K, Bartolozzi I, Schacht E, Bienstman P, Baets R (2007) Silicon-on-insulator microring resonator for sensitive and label-free biosensing. Opt Express 15:7610–7615
Shin Y, Perera AP, Kee JS, Song JF, Fang Q, Lo G-Q (2012) Label-free methyla-tion specific sensor based on silicon microring resonators for detection and quantification of DNA methylation biomarkers in bladder cancer. Sens Actuators B Chem 177:404–411
Liu Q, Xiaoguang T, Kim KW, Kee JS, Shin Y, Han K, Yoon Y-J, Lo G-Q, Park M (2013) Highly sensitive Mach-Zehnder interferometer biosensor based on silicon nitride slot waveguide. Sens Actuator B 188:681–688
Wang J, Dai D (2010) Highly sensitive Si nanowire-based optical sensor using a Mach-Zehnder interferometer coupled microring. Opt Lett 35(24):4229–4231
Xiong Y, Y WN (2013) Slotted silicon microring resonators with multimode interferometer couplers. In: Proceedings of IEEE International Conference Group IV Photon, vol 7, pp 118–119
Marsh OA, Xiong Y, Winnie NY (2017) Slot waveguide ring-assisted Mach–Zehnder interferometer for sensing applications. IEEE J Sel Top Quantum Electron 23(2)
Chao C-Y, Guo LJ (2002) Polymer microring resonators fabricated by nanoimprint technique. J Vac Sci Technol B Microelectron 20:2862–2866
Chao C-Y, Guo LJ (2004) Reduction of surface scattering loss in polymer microrings using thermal-reflow technique. IEEE Photon Technol Lett 16(6):1498–1500
Melloni A, Morichetti F, Martinelli M (2004) Polarization conversion in ring resonator phase shifter. Opt Lett 29:2785–2787
Chao C-Y, Fung W, Guo LJ (2006) Polymer microring resonators for biochemical sensing applications. IEEE J Sel Top Quantum Electron 12(1)
Barrios CA, Gylfason KB, Sa´nchez B, Griol A, Sohlstro¨m H, Holgado M, Casquel R (2007) Slot-waveguide biochemical sensor. Opt Lett 32(21):3080–3082
De Vos K, Bartolozzi I, Schacht E, Bienstman P, Baets R (2007) Silicon-on-insulator microring resonator for sensitive and label-free biosensing. Opt Express 15(12):7610–7615
Barrios CA, Banuls MJ, Gonzalez-Pedro V, Gylfason KB, Sanchez B, Griol A, Maquieira A, Sohlstrom H, Holgado M, Casquel R (2008) Label-free optical biosensing with slot-waveguides. Opt Lett 33(7):708–710
Claes T, Molera JG, De Vos K, Schacht E, Baets R, Bienstman P (2009) Label-free biosensing with a slot-waveguide-based ring resonator in silicon on insulator. IEEE Photon J 1(3)
Kargar A, Lee C (2009) Optical sensing by multiple-slot waveguide micro-ring resonators. In Nanotechnology, IEEE Conference, pp 240–242. IEEE
Gylfason KB, Carlborg CF et al (2010) On-chip temperature compensation in an integrated slot-waveguide ring resonator refractive index sensor array. Opt Express 18:3226–3237
Carlborg CF, Gylfason KB, Dortu F, Catala AM et al (2010) A packaged optical slot-waveguide ring resonator sensor array for multiplex label-free assays in labs-on-chips. Lab Chip 10:257–396
Yuan, Gao L, Chen Y, Liu X, Wang J, Wang Z (2014) Improvement of optical sensing performances of a double-slot-waveguide-based ring resonator sensor on silicon-on-insulator platform. Optik 125:850–854
Kaur G, Kaler RS (2017) Design and performance evaluation of hybrid optical sensor. Optik 140:508–514
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Mudgal, N., Agarwal, A., Saharia, A., Sahu, S., Ghunawat, A.K., Singh, G. (2020). Comparative Study of Interferometer and Ring Resonator Based Biosensors: A Review. In: Janyani, V., Singh, G., Tiwari, M., d’Alessandro, A. (eds) Optical and Wireless Technologies . Lecture Notes in Electrical Engineering, vol 546. Springer, Singapore. https://doi.org/10.1007/978-981-13-6159-3_44
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DOI: https://doi.org/10.1007/978-981-13-6159-3_44
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