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Target Organ Toxicology in Caenorhabditis elegans pp 123–146Cite as

Toxicity Induction in the Intestine and Epidermis in Nematodes Exposed to Environmental Toxicants or Stresses

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Abstract

In this chapter, we focused on the introduction of damage at different aspects on the intestine and epidermis, two important primary targeted organs for environmental toxicants. We first introduced and discussed the toxicity induction in the intestine of nematodes exposed to environmental toxicants or stresses with the concerns on activation of oxidative stress in the intestine, enhancement in intestinal permeability, damage on intestinal development, suppression of innate immune response, prolonged defecation behavior, and increase in fat storage. Moreover, we introduced and discussed the possible toxicity of environmental toxicants or stresses on the epidermis in nematodes under certain conditions.

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Authors and Affiliations

  1. School of Medicine, Southeast University, Nanjing, China

    Dayong Wang

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  1. Dayong Wang
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Wang, D. (2019). Toxicity Induction in the Intestine and Epidermis in Nematodes Exposed to Environmental Toxicants or Stresses. In: Target Organ Toxicology in Caenorhabditis elegans. Springer, Singapore. https://doi.org/10.1007/978-981-13-6010-7_5

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