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Textbook of Neuroanesthesia and Neurocritical Care pp 217–239Cite as

Hematological Management of Neurocritical Care Patients

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Abstract

Intracranial hemorrhage is a devastating complication of antithrombotic use, systemic coagulopathies, or bleeding diatheses. Physiological derangements, such as autoimmune dysfunction, acute infection, organ dysfunction, systemic disease, and therapeutic medications, often lead to dysfunctional hemostasis in the intensive care unit (ICU). These derangements pose complex management dilemmas, especially when it results in intracranial hemorrhage, as coagulopathy worsens neurologic prognosis and functional outcome. Increased utilization of antithrombotic medications mandates a thorough understanding of these treatments as well as their reversal agents, as prompt reversal may limit volume of hemorrhage. This chapter will focus on acquired coagulopathies that are associated with increased bleeding risk that result in various forms of intracranial hemorrhage.

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Authors and Affiliations

  1. Department of Neurology, University of Pennsylvania, Philadelphia, PA, USA

    Aleksey Tadevosyan, Izad-Yar Rasheed & Monisha A. Kumar

  2. Department of Anesthesiology and Neurosurgery, Baylor College of Medicine, Houston, TX, USA

    Jovany Cruz Navarro

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  1. Aleksey Tadevosyan
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  4. Monisha A. Kumar
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Correspondence to Monisha A. Kumar .

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  1. Department of Neuroanaesthesiology and Critical Care, All India Institute of Medical Sciences, New Delhi, India

    Hemanshu Prabhakar

  2. Division of Neuroanesthesiology, Department of Anesthesiology, Sher-i-Kashmir Institute of Medical Sciences, Soura, Srinagar, Jammu and Kashmir, India

    Zulfiqar Ali

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Tadevosyan, A., Navarro, J.C., Rasheed, IY., Kumar, M.A. (2019). Hematological Management of Neurocritical Care Patients. In: Prabhakar, H., Ali, Z. (eds) Textbook of Neuroanesthesia and Neurocritical Care. Springer, Singapore. https://doi.org/10.1007/978-981-13-3390-3_16

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