Abstract
This chapter describes the overviews of biomimetic medical materials which covers innovation and significance of terminology, diverse fabrication methods, and technologies ranges from nanotechnology to 3D printing to develop biomimetic materials for medical applications. It also depicts specific fundamental characteristics required for a material to be a model biomimetic material for particular medical application. It basically outlines current statuses of biomimetic medical materials used for tissue engineering and regenerative medicine, drug/protein delivery, bioimaging, biosensing, and 3D bioprinting technology. It also illustrates the effect of functionalization of a material through chemical and biological approaches towards different applications. Not only, the key properties and potential applications of the biomimetic materials, but it also explains the protection and utilization of intellectual property associated with biomedical materials.
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References
Aime S, Frullano L, Geninatti Crich S (2002) Compartmentalization of a gadolinium complex in the apoferritin cavity: a route to obtain high relaxivity contrast agents for magnetic resonance imaging. Angew Chem Int Ed 41(6):1017–1019
An X, Butler TW, Washington M, Nayak SK, Kar S (2011) Optical and sensing properties of 1-pyrenecarboxylic acid-functionalized graphene films laminated on polydimethylsiloxane membranes. ACS Nano 5(2):1003–1011
Bacakova L, Novotná K, Parizek M (2014) Polysaccharides as cell carriers for tissue engineering: the use of cellulose in vascular wall reconstruction. Physiol Res 63:S29
Balandin AA, Ghosh S, Bao W, Calizo I, Teweldebrhan D, Miao F, Lau CN (2008) Superior thermal conductivity of single-layer graphene. Nano Lett 8(3):902–907
Bar-Cohen Y (2006) Biomimetics: biologically inspired technologies. CRC/Taylor & Francis, Boca Raton isbn:9780849331633
Bello OS, Adegoke KA, Oyewole RO (2013) Biomimetic materials in our world: a review. IOSR J Appl Chem (IOSR-JAC) 5:22–35
Benyus J (1997) Biomimicry: innovation inspired by nature. William Morrow & Company Inc, New York, isbn:978–0688–16099-9
Betre H, Ong SR, Guilak F, Chilkoti A, Fermor B, Setton LA (2006) Chondrocytic differentiation of human adipose-derived adult stem cells in elastin-like polypeptide. Biomaterials 27(1):91–99
Bhattacharya P, Du D, Lin Y (2014) Bioinspired nanoscale materials for biomedical and energy applications. J R Soc Interface 11(95):20131067
Bode SA, Minten IJ, Nolte RJ, Cornelissen JJ (2011) Reactions inside nanoscale protein cages. Nanoscale 3(6):2376–2389
Boland T, Tao X, Damon BJ, Manley B, Kesari P, Jalota S, Bhaduri S (2007) Drop-on-demand printing of cells and materials for designer tissue constructs. Mater Sci Eng C 27(3):372–376
Branco MC, Schneider JP (2009) Self-assembling materials for therapeutic delivery. Acta Biomater 5(3):817–831
Caplan AI (2007) Adult mesenchymal stem cells for tissue engineering versus regenerative medicine. J Cell Physiol 213(2):341–347
Chacko RT, Ventura J, Zhuang J, Thayumanavan S (2012) Polymer nanogels: a versatile nanoscopic drug delivery platform. Adv Drug Deliv Rev 64(9):836–851
Chen A, Bao Y, Ge X, Shin Y, Du D, Lin Y (2012) Magnetic particle-based immunoassay of phosphorylated p53 using protein cage template lead phosphate and carbon nanospheres for signal amplification. RSC Adv 2(29):11029–11034
Chen C, Bang S, Cho Y, Lee S, Lee I, Zhang S, Noh I (2016) Research trends in biomimetic medical materials for tissue engineering: 3D bioprinting, surface modification, nano/micro-technology and clinical aspects in tissue engineering of cartilage and bone. Biomater Res 20(1):10
Chen F, Ni Y, Liu B, Zhou T, Yu C, Su Y, Zhu X, Yu X, Zhou Y (2017) Self-crosslinking and injectable hyaluronic acid/RGD-functionalized pectin hydrogel for cartilage tissue engineering. Carbohydr Polym 166:31–44
Chilkoti A, Christensen T, MacKay JA (2006) Stimulus responsive elastin biopolymers: applications in medicine and biotechnology. Curr Opin Chem Biol 10(6):652–657
Christensen K, Xu C, Chai W, Zhang Z, Fu J, Huang Y (2015) Freeform inkjet printing of cellular structures with bifurcations. Biotechnol Bioeng 112(5):1047–1055
Chung L, Maestas DR Jr, Housseau F, Elisseeff JH (2017) Key players in the immune response to biomaterial scaffolds for regenerative medicine. Adv Drug Deliv Rev 114:184–192
Cui H, Nowicki M, Fisher JP, Zhang LG (2017) 3D bioprinting for organ regeneration. Adv Healthc Mater 6(1):1601118
Eggermont M, (2008) Biomimetics as problem-solving, creativity and innovation tool. CDEN/C 2E2. Winnipeg, University of Manitoba, Canada, 114:59–67
Entekhabi E, Nazarpak MH, Moztarzadeh F, Sadeghi A (2016) Design and manufacture of neural tissue engineering scaffolds using hyaluronic acid and polycaprolactone nanofibers with controlled porosity. Mater Sci Eng C 69:380–387
Erik D, Stephen M (2002) Bio-inspired materials chemistry. Adv Mater 14:1–14
Fan K, Cao C, Pan Y, Lu D, Yang D, Feng J, Song L, Liang M, Yan X (2012) Magnetoferritin nanoparticles for targeting and visualizing tumour tissues. Nat Nanotechnol 7(7):459
Fan M, Ma Y, Zhang Z, Mao J, Tan H, Hu X (2015) Biodegradable hyaluronic acid hydrogels to control release of dexamethasone through aqueous Diels–Alder chemistry for adipose tissue engineering. Mater Sci Eng C 56:311–317
Gao W (2015) The chemistry of graphene oxide. In: Graphene oxide. Springer, Cham, pp 61–95
Gardner AB, Lee SK, Woods EC, Acharya AP (2013) Biomaterials-based modulation of the immune system. Bio Med Res Int Article ID 732182, 2013:1–7
Geim AK, Novoselov KS (2007) The rise of graphene. Nat Mater 6(3):183
Gelain F, Horii A, Zhang S (2007) Designer self-assembling peptide scaffolds for 3-D tissue cell cultures and regenerative medicine. Macromol Biosci 7(5):544–551
Georgakilas V, Otyepka M, Bourlinos AB, Chandra V, Kim N, Kemp KC, Hobza P, Zboril R, Kim KS (2012) Functionalization of graphene: covalent and non-covalent approaches, derivatives and applications. Chem Rev 112(11):6156–6214
Groen N, Guvendiren M, Rabitz H, Welsh WJ, Kohn J, de Boer J (2016) Stepping into the omics era: opportunities and challenges for biomaterials science and engineering. Acta Biomater 34:133–142
Gu BK, Choi DJ, Park SJ, Kim MS, Kang CM, Kim CH (2016) 3-dimensional bioprinting for tissue engineering applications. Biomater Res 20(1):12. https://doi.org/10.1186/s40824-016-0058-2
Gudapati H, Dey M, Ozbolat I (2016) A comprehensive review on droplet-based bioprinting: past, present and future. Biomaterials 102:20–42
Guvendiren M, Molde J, Soares RM, Kohn J (2016) Designing biomaterials for 3D printing. ACS Biomater Sci Eng 2(10):1679–1693
Harrison PM, Arosio P (1996) The ferritins: molecular properties, iron storage function and cellular regulation. Biochim Biophys Acta 1275(3):161–203
Hatayama T, Nakada A, Nakamura H, Mariko W, Tsujimoto G, Nakamura T (2017) Regeneration of gingival tissue using in situ tissue engineering with collagen scaffold. Oral Surg, Oral Med, Oral Pathol, Oral Radiol 124(4):348–354
Helms B, Meijer EW (2006) Dendrimers at work. SCIENCE-NEW YORK THEN WASHINGTON 313(5789):929
Hengstenberg A, Bloch A, Dietzel D, Schuhmann W (2001) Spatially resolved detection of neurotransmitter secretion from individual cells by means of scanning electrochemical microscopy. Angew Chem Int Ed 40:905–908
Highley CB, Rodell CB, Burdick JA (2015) Direct 3D printing of shear-thinning hydrogels into self-healing hydrogels. Adv Mater 27(34):5075–5079
Hoffman AS (2012) Hydrogels for biomedical applications. Adv Drug Deliv Rev 64:18–23
Hölzl K, Lin S, Tytgat L, Van Vlierberghe S, Gu L, Ovsianikov A (2016) Bioink properties before, during and after 3D bioprinting. Biofabrication 8(3):032002
Hong S, Sycks D, Chan HF, Lin S, Lopez GP, Guilak F, Leong KW, Zhao X (2015) 3D printing of highly stretchable and tough hydrogels into complex, cellularized structures. Adv Mater 27(27):4035–4040
Hornick JF, Rajan K (2015) Chapter 16: intellectual property in 3d printing and nanotechnology, 3D bioprinting and nanotechnology in tissue engineering. John F. Hornick. Published by Elsevier Inc.
Hou Y, Cai K, Li J, Chen X, Lai M, Hu Y, Luo Z, Ding X, Xu D (2013) Effects of titanium nanoparticles on adhesion, migration, proliferation, and differentiation of mesenchymal stem cells. Int J Nanomedicine 8:3619
Hsieh PC, MacGillivray C, Gannon J, Cruz FU, Lee RT (2006) Local controlled intramyocardial delivery of platelet-derived growth factor improves postinfarction ventricular function without pulmonary toxicity. Circulation 114(7):637–644
Hu SH, Chen YW, Hung WT, Chen IW, Chen SY (2012) Quantum-dot-tagged reduced graphene oxide nanocomposites for bright fluorescence bioimaging and Photothermal therapy monitored in situ. Adv Mater 24(13):1748–1754
Hu C, Liu Y, Yang Y, Cui J, Huang Z, Wang Y, Yang L, Wang H, Xiao Y, Rong J (2013) One-step preparation of nitrogen-doped graphene quantum dots from oxidized debris of graphene oxide. J Mater Chem B 1(1):39–42
Huang X, Qi X, Boey F, Zhang H (2012) Graphene-based composites. Chem Soc Rev 41(2):666–686
Jakab K, Norotte C, Marga F, Murphy K, Vunjak-Novakovic G, Forgacs G (2010) Tissue engineering by self-assembly and bio-printing of living cells. Biofabrication 2(2):022001
Jang J, Kim TG, Kim BS, Kim SW, Kwon SM, Cho DW (2016) Tailoring mechanical properties of decellularized extracellular matrix bioink by vitamin B2-induced photo-crosslinking. Acta Biomater 33:88–95
Jang J, Park HJ, Kim SW, Kim H, Park JY, Na SJ, Kim HJ, Park MN, Choi SH, Park SH, Kim SW (2017) 3D printed complex tissue construct using stem cell-laden decellularized extracellular matrix bioinks for cardiac repair. Biomaterials 112:264–274
Jeong B, Akter R, Han OH, Rhee CK, Rahman MA (2013) Increased electrocatalyzed performance through dendrimer-encapsulated gold nanoparticles and carbon nanotube-assisted multiple bienzymatic labels: highly sensitive electrochemical immunosensor for protein detection. Anal Chem 85(3):1784–1791
Ji S, Guvendiren M (2017) Recent advances in bioink design for 3D bioprinting of tissues and organs. Front Bioeng Biotechnol 5:23
Julian FVV, Olga AB, Nikolaj RB, Adrian B, Anja KP (2006) Biomimetics: its practice and theory. J R Soc Interface 3:471–482
Jung CS, Kim BK, Lee J, Min BH, Park SH (2017) Development of printable natural cartilage matrix bioink for 3D printing of irregular tissue shape. Tissue Eng Regen Med 15:1–8. https://doi.org/10.1007/s13770-017-0104-8
Kang X, Wang J, Wu H, Aksay IA, Liu J, Lin Y (2009) Glucose oxidase–graphene–chitosan modified electrode for direct electrochemistry and glucose sensing. Biosens Bioelectron 25(4):901–905
Kersey FR, Merkel TJ, Perry JL, Napier ME, DeSimone JM (2012) Effect of aspect ratio and deformability on nanoparticle extravasation through nanopores. Langmuir 28(23):8773–8781
Kim JE, Kim SH, Jung Y (2016) Current status of three-dimensional printing inks for soft tissue regeneration. Tissue Eng Regen Med 13(6):636–646
Kolos E, Ruys AJ (2013) Biomimetic scaffold materials used in tissue engineering. J Biomim Biomater Tissue Eng 18:e101. https://doi.org/10.4172/1662-100X.1000e101
Kutlusoy T, Oktay B, Apohan NK, Süleymanoğlu M, Kuruca SE (2017) Chitosan-co-hyaluronic acid porous cryogels and their application in tissue engineering. Int J Biol Macromol 103:366–378
Lee WC, Loh KP, Lim CT (2018) When stem cells meet graphene: opportunities and challenges in regenerative medicine. Biomaterials 155:236–250
Li M, Yang X, Ren J, Qu K, Qu X (2012) Using graphene oxide high near-infrared absorbance for Photothermal treatment of Alzheimer's disease. Adv Mater 24(13):1722–1728
Li N, Zhang Q, Gao S, Song Q, Huang R, Wang L, Liu L, Dai J, Tang M, Cheng G (2013) Three-dimensional graphene foam as a biocompatible and conductive scaffold for neural stem cells. Sci Rep 3:1604
Li C, Faulkner-Jones A, Dun AR, Jin J, Chen P, Xing Y, Yang Z, Li Z, Shu W, Liu D, Duncan RR (2015) Rapid formation of a supramolecular polypeptide–DNA hydrogel for in situ three-dimensional multilayer bioprinting. Angew Chem Int Ed 54(13):3957–3961
Liao S, Chan CK, Ramakrishna S (2008) Stem cells and biomimetic materials strategies for tissue engineering. Mater Sci Eng C 28(8):1189–1202
Lim KS, Schon BS, Mekhileri NV, Brown GC, Chia CM, Prabakar S, Hooper GJ, Woodfield TB (2016) New visible-light photoinitiating system for improved print fidelity in gelatin-based bioinks. ACS Biomater Sci Eng 2(10):1752–1762
Lin X, Xie J, Niu G, Zhang F, Gao H, Yang M, Quan Q, Aronova MA, Zhang G, Lee S, Leapman R (2011) Chimeric ferritin nanocages for multiple function loading and multimodal imaging. Nano Lett 11(2):814–819
Liu G, Lin Y (2007) Electrochemical quantification of single-nucleotide polymorphisms using nanoparticle probes. J Am Chem Soc 129(34):10394–10401
Liu JC, Heilshorn SC, Tirrell DA (2004) Comparative cell response to artificial extracellular matrix proteins containing the RGD and CS5 cell-binding domains. Biomacromolecules 5(2):497–504
Liu G, Wang J, Lea SA, Lin Y (2006a) Bioassay labels based on apoferritin nanovehicles. Chembiochem 7(9):1315–1319
Liu G, Wu H, Wang J, Lin Y (2006b) Apoferritin-templated synthesis of metal phosphate nanoparticle labels for electrochemical immunoassay. Small 2(10):1139–1143
Liu Z, Robinson JT, Sun X, Dai H (2008) PEGylated nanographene oxide for delivery of water-insoluble cancer drugs. J Am Chem Soc 130(33):10876–10877
Liu Y, Dong X, Chen P (2012) Biological and chemical sensors based on graphene materials. Chem Soc Rev 41(6):2283–2307
Loessner D, Meinert C, Kaemmerer E, Martine LC, Yue K, Levett PA, Klein TJ, Melchels FP, Khademhosseini A, Hutmacher DW (2016) Functionalization, preparation and use of cell-laden gelatin methacryloyl–based hydrogels as modular tissue culture platforms. Nat Protoc 11(4):727
Maeda M, Tani S, Sano A, Fujioka K (1999) Microstructure and release characteristics of the minipellet, a collagen-based drug delivery system for controlled release of protein drugs. J Control Release 62(3):313–324
MaHam A, Tang Z, Wu H, Wang J, Lin Y (2009) Protein-based nanomedicine platforms for drug delivery. Small 5(15):1706–1721
Mazur A, Litt I, Shorr E (1950) Chemical properties of ferritin and their relation to its vasodepressor activity. J Biol Chem 187:473–484
Müller M, Becher J, Schnabelrauch M, Zenobi-Wong M (2015) Nanostructured Pluronic hydrogels as bioinks for 3D bioprinting. Biofabrication 7(3):035006
Murphy SV, Atala A (2014) 3D bioprinting of tissues and organs. Nat Biotechnol 32(8):773
Nagarajan R (2008) Nanoparticles: building blocks for nanotechnology, nanoparticles: synthesis, stabilization, passivation, and functionalization, chapter 1: ACS Symposium Series, 996:2–14. ISBN:9780841269699eISBN:9780841221390
Nakamura T, Konno K (1954) Studies on ferritin. J Biochem 41(4):499–502
Napier ME, JM DS (2007) Nanoparticle drug delivery platform. J Macromol Sci Part C: Polym Rev 47(3):321–327
Nassar W, El-Ansary M, Sabry D, Mostafa MA, Fayad T, Kotb E, Temraz M, Saad AN, Essa W, Adel H (2017) Erratum to: umbilical cord mesenchymal stem cells derived extracellular vesicles can safely ameliorate the progression of chronic kidney diseases. Biomater Res 21(1):3
Nayak TR, Andersen H, Makam VS, Khaw C, Bae S, Xu X, Ee PL, Ahn JH, Hong BH, Pastorin G, Ozyilmaz B (2011) Graphene for controlled and accelerated osteogenic differentiation of human mesenchymal stem cells. ACS Nano 5(6):4670–4678
Nguyen DG, Funk J, Robbins JB, Crogan-Grundy C, Presnell SC, Singer T, Roth AB (2016) Bioprinted 3D primary liver tissues allow assessment of organ-level response to clinical drug induced toxicity in vitro. PLoS One 11(7):e0158674
Oh JK, Drumright R, Siegwart DJ, Matyjaszewski K (2008) The development of microgels/nanogels for drug delivery applications. Pro Polym Sci 33(4):448–477
Ouyang L, Highley CB, Rodell CB, Sun W, Burdick JA (2016) 3D printing of shear-thinning hyaluronic acid hydrogels with secondary cross-linking. ACS Biomater Sci Eng 2(10):1743–1751
Ozbolat IT, Moncal KK, Gudapati H (2017) Evaluation of bioprinter technologies. Addit Manuf 13:179–200
Pan D, Zhang J, Li Z, Wu M (2010) Hydrothermal route for cutting graphene sheets into blue-luminescent graphene quantum dots. Adv Mater 22(6):734–738
Pan T, Song W, Cao X, Wang Y (2016) 3D bioplotting of gelatin/alginate scaffolds for tissue engineering: influence of crosslinking degree and pore architecture on physicochemical properties. J Mater Sci Technol 32(9):889–900
Park S, Ruoff RS (2009) Chemical methods for the production of graphenes. Nat Nanotechnol 4(4):217
Park JH, Jang J, Lee JS, Cho DW (2016) Current advances in three-dimensional tissue/organ printing. Tissue Eng Regen Med 13(6):612–621
Pati F, Jang J, Ha DH, Kim SW, Rhie JW, Shim JH, Kim DH, Cho DW (2014) Printing three-dimensional tissue analogues with decellularized extracellular matrix bioink. Nat Commun 5:3935
Patterson J, Martino MM, Hubbell JA (2010) Biomimetic materials in tissue engineering. Mater Today 13(1–2):14–22
Peng J, Gao W, Gupta BK, Liu Z, Romero-Aburto R, Ge L, Song L, Alemany LB, Zhan X, Gao G, Vithayathil SA (2012) Graphene quantum dots derived from carbon fibers. Nano Lett 12(2):844–849
Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD, Moorman MA, Simonetti DW, Craig S, Marshak DR (1999) Multilineage potential of adult human mesenchymal stem cells. Science 284(5411):143–147
Ramón-Azcón J, Ahadian S, Estili M, Liang X, Ostrovidov S, Kaji H, Shiku H, Ramalingam M, Nakajima K, Sakka Y, Khademhosseini A (2013) Dielectrophoretically aligned carbon nanotubes to control electrical and mechanical properties of hydrogels to fabricate contractile muscle myofibers. Adv Mater 25(29):4028–4034
Raphael B, Khalil T, Workman VL, Smith A, Brown CP, Streuli C, Saiani A, Domingos M (2017) 3D cell bioprinting of self-assembling peptide-based hydrogels. Mater Lett 190:103–106
Rashid ST, Alexander GJ (2013) Induced pluripotent stem cells: from Nobel prizes to clinical applications. J Hepatol 58(3):625–629
Ribeiro M, de Moraes MA, Beppu MM, Garcia MP, Fernandes MH, Monteiro FJ, Ferraz MP (2015) Development of silk fibroin/nanohydroxyapatite composite hydrogels for bone tissue engineering. Eur Polym J 67:66–77
Rolland JP, Maynor BW, Euliss LE, Exner AE, Denison GM, DeSimone JM (2005) Direct fabrication and harvesting of monodisperse, shape-specific nanobiomaterials. J Am Chem Soc 127(28):10096–10100
Schneider A, Garlick JA, Egles C (2008) Self-assembling peptide nanofiber scaffolds accelerate wound healing. PLoS One 3(1):e1410
Scuderi P, Lam K, Ryan K, Petersen E, Sterling K, Finley P, Ray CG, Slymen D, Salmon S (1986 Dec 13) Raised serum levels of tumour necrosis factor in parasitic infections. Lancet 328(8520):1364–1365
Segers VF, Tokunou T, Higgins LJ, MacGillivray C, Gannon J, Lee RT (2007) Local delivery of protease-resistant stromal cell derived factor-1 for stem cell recruitment after myocardial infarction. Circulation 116(15):1683–1692
Shafiee A, Atala A (2016) Printing technologies for medical applications. Trends Mol Med 22(3):254–265
Shan C, Yang H, Song J, Han D, Ivaska A, Niu L (2009) Direct electrochemistry of glucose oxidase and biosensing for glucose based on graphene. Anal Chem 81(6):2378–2382
Shao Y, Zhang S, Engelhard MH, Li G, Shao G, Wang Y, Liu J, Aksay IA, Lin Y (2010) Nitrogen-doped graphene and its electrochemical applications. J Mater Chem 20(35):7491–7496
Sharma AK, Gothwal A, Kesharwani P, Alsaab H, Iyer AK, Gupta U (2017) Dendrimer nanoarchitectures for cancer diagnosis and anticancer drug delivery. Drug Discov Today 22(2):314–326
Sheehy EJ, Cunniffe GM, O'Brien FJ (2018) Collagen-based biomaterials for tissue regeneration and repair. In: Peptides and proteins as biomaterials for tissue regeneration and repair. Woodhead Publishing, Duxford, pp 127–150
Shin SR, Bae H, Cha JM, Mun JY, Chen YC, Tekin H, Shin H, Farshchi S, Dokmeci MR, Tang S, Khademhosseini A (2011) Carbon nanotube reinforced hybrid microgels as scaffold materials for cell encapsulation. ACS Nano 6(1):362–372
Shin YC, Kim J, Kim SE, Song SJ, Hong SW, Oh JW, Lee J, Park JC, Hyon SH, Han DW (2017) RGD peptide and graphene oxide co-functionalized PLGA nanofiber scaffolds for vascular tissue engineering. Regen biomater 4(3):159–166
Silva GA, Czeisler C, Niece KL, Beniash E, Harrington DA, Kessler JA, Stupp SI (2004) Selective differentiation of neural progenitor cells by high-epitope density nanofibers. Science 303(5662):1352–1355
Soni KS, Desale SS, Bronich TK (2016) Nanogels: an overview of properties, biomedical applications and obstacles to clinical translation. J Control Release 240:109–126
Suci PA, Kang S, Young M, Douglas T (2009) A streptavidin-protein cage janus particle for polarized targeting and modular functionalization. J Am Chem Soc 131:9164–9165
Sun X, Liu Z, Welsher K, Robinson JT, Goodwin A, Zaric S, Dai H (2008) Nano-graphene oxide for cellular imaging and drug delivery. Nano Res 1(3):203–212
Takahashi K, Yamanaka S (2006) Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126(4):663–676
Tan YJ, Tan X, Yeong WY, Tor SB (2016) Hybrid microscaffold-based 3D bioprinting of multi-cellular constructs with high compressive strength: a new biofabrication strategy. Sci Rep 6:39140
Tang Z, Wu H, Zhang Y, Li Z, Lin Y (2011) Enzyme-mimic activity of ferric nano-core residing in ferritin and its biosensing applications. Anal Chem 83(22):8611–8616
Tetsuka H, Asahi R, Nagoya A, Okamoto K, Tajima I, Ohta R, Okamoto A (2012) Optically tunable amino-functionalized graphene quantum dots. Adv Mater 24(39):5333–5338
Tomalia DA, Naylor AM, Goddard WA (1990) Starburst dendrimers: molecular-level control of size, shape, surface chemistry, topology, and flexibility from atoms to macroscopic matter. Angew Chem Int Ed 29(2):138–175
Toole BP (2004) Hyaluronan: from extracellular glue to pericellular cue. Nat Rev Cancer 4(7):528
Turyanska L, Bradshaw TD, Sharpe J, Li M, Mann S, Thomas NR, Patane A (2009) The biocompatibility of Apoferritin-encapsulated PbS quantum dots. Small 5(15):1738–1741
Uchida M, Klem MT, Allen M, Suci P, Flenniken M, Gillitzer E, Varpness Z, Liepold LO, Young M, Douglas T (2007) Biological containers: protein cages as multifunctional Nanoplatforms. Adv Mater 19:1025–1042
Vunjak-Novakovic G, Scadden DT (2011) Biomimetic platforms for human stem cell research. Cell Stem Cell 8(3):252–261
Walimbe T, Panitch A, Sivasankar PM (2017) A review of hyaluronic acid and hyaluronic acid-based hydrogels for vocal fold tissue engineering. J Voice 31(4):416–423
Wang Y, Li Y, Tang L, Lu J, Li J (2009) Application of graphene-modified electrode for selective detection of dopamine. Electrochem Commun 11(4):889–892
Wang Y, Li Z, Hu D, Lin CT, Li J, Lin Y (2010a) Aptamer/graphene oxide nanocomplex for in situ molecular probing in living cells. J Am Chem Soc 132(27):9274–9276
Wang Y, Shao Y, Matson DW, Li J, Lin Y (2010b) Nitrogen-doped graphene and its application in electrochemical biosensing. ACS Nano 4(4):1790–1798
Wang C, Liu N, Allen R, Tok JB, Wu Y, Zhang F, Chen Y, Bao Z (2013a) A rapid and efficient self-healing Thermo-reversible elastomer crosslinked with graphene oxide. Adv Mater 25(40):5785–5790
Wang X, Cai X, Hu J, Shao N, Wang F, Zhang Q, Xiao J, Cheng Y (2013b) Glutathione-triggered “off–on” release of anticancer drugs from dendrimer-encapsulated gold nanoparticles. J Am Chem Soc 135(26):9805–9810
Wang X, Zhang Y, Li T, Tian W, Zhang Q, Cheng Y (2013c) Generation 9 polyamidoamine dendrimer encapsulated platinum nanoparticle mimics catalase size, shape, and catalytic activity. Langmuir 29(17):5262–5270
Wang Y, Li Z, Weber TJ, Hu D, Lin CT, Li J, Lin Y (2013d) In situ live cell sensing of multiple nucleotides exploiting DNA/RNA aptamers and graphene oxide nanosheets. Anal Chem 85(14):6775–6782
Weiss NO, Zhou H, Liao L, Liu Y, Jiang S, Huang Y, Duan X (2012) Graphene: an emerging electronic material. Adv Mater 224(43):5782–5825
Wu P, Qian Y, Du P, Zhang H, Cai C (2012) Facile synthesis of nitrogen-doped graphene for measuring the releasing process of hydrogen peroxide from living cells. J Mater Chem 22(13):6402–6412
Wüst S, Müller R, Hofmann S (2015) 3D bioprinting of complex channels—effects of material, orientation, geometry, and cell embedding. J Biomed Mater Res A 103(8):2558–2570
Xie X, Zhou Y, Bi H, Yin K, Wan S, Sun L (2013) Large-range control of the microstructures and properties of three-dimensional porous graphene. Sci Rep 3:2117
Yang K, Hu L, Ma X, Ye S, Cheng L, Shi X, Li C, Li Y, Liu Z (2012) Multimodal imaging guided photothermal therapy using functionalized graphene nanosheets anchored with magnetic nanoparticles. Adv Mater 24(14):1868–1872
Yang K, Feng L, Shi X, Liu Z (2013a) Nano-graphene in biomedicine: theranostic applications. Chem Soc Rev 42(2):530–547
Yang Y, Asiri AM, Tang Z, Du D, Lin Y (2013b) Graphene based materials for biomedical applications. Mater Today 16(10):365–373
Zhang S, Holmes TC, DiPersio CM, Hynes RO, Su X, Rich A (1995) Self-complementary oligopeptide matrices support mammalian cell attachment. Biomaterials 16(18):1385–1393
Zhang L, Xia J, Zhao Q, Liu L, Zhang Z (2010) Functional graphene oxide as a nanocarrier for controlled loading and targeted delivery of mixed anticancer drugs. Small 6(4):537–544
Zhang L, Lu Z, Zhao Q, Huang J, Shen H, Zhang Z (2011a) Enhanced chemotherapy efficacy by sequential delivery of siRNA and anticancer drugs using PEI-grafted graphene oxide. Small 7(4):460–464
Zhang W, Guo Z, Huang D, Liu Z, Guo X, Zhong H (2011b) Synergistic effect of chemo-photothermal therapy using PEGylated graphene oxide. Biomaterials 32(33):8555–8561
Zhang Y, Tang Z, Wang J, Wu H, Lin CT, Lin Y (2011c) Apoferritin nanoparticle: a novel and biocompatible carrier for enzyme immobilization with enhanced activity and stability. J Mater Chem 21(43):17468–17475
Zhang M, Bai L, Shang W, Xie W, Ma H, Fu Y, Fang D, Sun H, Fan L, Han M, Liu C (2012) Facile synthesis of water-soluble, highly fluorescent graphene quantum dots as a robust biological label for stem cells. J Mater Chem 22(15):7461–7467
Zhang H, Zhai Y, Wang J, Zhai G (2016) New progress and prospects: the application of nanogel in drug delivery. Mater Sci Eng C 60:560–568
Zhen Z, Tang W, Chen H, Lin X, Todd T, Wang G, Cowger T, Chen X, Xie J (2013) RGD-modified apoferritin nanoparticles for efficient drug delivery to tumors. ACS Nano 7(6):4830–4837
Zhou M, Zhai Y, Dong S (2009) Electrochemical sensing and biosensing platform based on chemically reduced graphene oxide. Anal Chem 81(14):5603–5613
Zhu J, Tang C, Kottke-Marchant K, Marchant RE (2009) Design and synthesis of biomimetic hydrogel scaffolds with controlled organization of cyclic RGD peptides. Bioconjug Chem 20(2):333–339
Zhu Y, Murali S, Cai W, Li X, Suk JW, Potts JR, Ruoff RS (2010) Graphene and graphene oxide: synthesis, properties, and applications. Adv Mater 22(35):3906–3924
Zhu S, Zhang J, Qiao C, Tang S, Li Y, Yuan W, Li B, Tian L, Liu F, Hu R, Gao H (2011) Strongly green-photoluminescent graphene quantum dots for bioimaging applications. Chem comm 47(24):6858–6860
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This work was supported by the National Research Foundation of Korea (NRF) Grant (2015R1A2A1A10054592).
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Das, D., Noh, I. (2018). Overviews of Biomimetic Medical Materials. In: Noh, I. (eds) Biomimetic Medical Materials. Advances in Experimental Medicine and Biology, vol 1064. Springer, Singapore. https://doi.org/10.1007/978-981-13-0445-3_1
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