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Cepharanthine

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Natural Small Molecule Drugs from Plants

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Abstract

Cepharanthine is diclofenac quinoline alkaloid isolated from rhizome of Stephania japonica. It could stimulate the reticuloendothelial system, then activate hematopoietic tissue, and promote myeloproliferation. The major clinical application of cepharanthine is to improve their immunity impaired by chemotherapy or radiotherapy in tumor patients. In addition, cepharanthine can increase the sensitivity of antitumor drugs. Now, it is commonly used as an adjuvant drug for anticancer treatment. In addition, it is also used as anti-pneumoconiosis drugs in China.

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Authors and Affiliations

  1. State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica & Neuroscience Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

    Shi-Feng Chu & Nai-Hong Chen

  2. Beijing Key Laboratory of Drug Targets Identification and Drug Screening, Centre for Pharmaceutical Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

    Ling-Lei Kong

Authors
  1. Shi-Feng Chu
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  2. Ling-Lei Kong
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  3. Nai-Hong Chen
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Corresponding author

Correspondence to Nai-Hong Chen .

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© 2018 Springer Nature Singapore Pte Ltd. and People's Medical Publishing House, PR of China

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Chu, SF., Kong, LL., Chen, NH. (2018). Cepharanthine. In: Natural Small Molecule Drugs from Plants. Springer, Singapore. https://doi.org/10.1007/978-981-10-8022-7_82

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