Abstract
Colorectal cancer (CRC) is a prominent source of cancer-related deaths across the world. AP-1 is involved in CRC growth and metastasis. AP-1 is a transcription factor that regulates many oncogenic transduction pathways. In the current chapter, we discuss the importance of AP-1 on CRC growth and metastasis. Additionally, we discuss the mechanism of genistein, a tyrosine kinase inhibitor, and its effect on CRC treatment.
The original version of this chapter was revised. The book was inadvertently published without Abstracts and Keywords, which are now included in all the chapters. An erratum to this chapter can be found at https://doi.org/10.1007/978-981-10-6728-0_39
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Merchant, N., Prasad, G.L.V., Nagaraju, G.P. (2017). Genistein and Its Role in Regulation of AP-1 in Colorectal Cancer. In: Nagaraju, G., Bramhachari, P. (eds) Role of Transcription Factors in Gastrointestinal Malignancies. Springer, Singapore. https://doi.org/10.1007/978-981-10-6728-0_8
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DOI: https://doi.org/10.1007/978-981-10-6728-0_8
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