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Telocytes in Exocrine Glands Stroma

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Book cover Telocytes

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 913))

Abstract

Stroma is viewed as the supportive framework of a predominant epithelial organ, comprising mostly of connective tissue, blood vessels and nerves. Since the discovery of telocytes one decade ago (Popescu and Faussone-Pellegrini J Cell Mol Med 2010;14(4):729–40), their presence was proven in several exocrine gland stromata, including major and minor salivary glands, mammary glands as well as exocrine pancreas.

Telocytes have been found in a close connection with acinar and ductal structures but also with their stromal neighbours – nerves, blood vessels or other connective elements, either cells or collagen fibres.

The approaches used to reveal the telocytes’ location were immunohistochemistry and electron microscopy.

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References

  1. Alunno A, et al. Telocytes in minor salivary glands of primary Sjögren’s syndrome: association with the extent of inflammation and ectopic lymphoid neogenesis. J Cell Mol Med. 2015;19(7):1689–96.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Gherghiceanu M, Popescu LM. Interstitial Cajal-like cells (ICLC) in human resting mammary gland stroma. Transmission electron microscope (TEM) identification. J Cell Mol Med. 2005;9(4):893–910.

    Article  PubMed  Google Scholar 

  3. Nicolescu MI. Telocytes in pancreas and salivary glands [PhD Thesis]. Bucharest: Carol Davila University of Medicine and Pharmacy; 2012.

    Google Scholar 

  4. Nicolescu MI, Popescu LM. Telocytes in the interstitium of human exocrine pancreas: ultrastructural evidence. Pancreas. 2012;41(6):949–56.

    Article  PubMed  Google Scholar 

  5. Nicolescu MI, et al. Telocytes in parotid glands. Anat Rec. 2012;295(3):378–85.

    Article  Google Scholar 

  6. Petre N, et al. Telocytes of the mammary gland stroma. Folia Morphol. 2016;75(2):224–31.

    Google Scholar 

  7. Popescu LM, Faussone-Pellegrini M-S. TELOCYTES – a case of serendipity: the winding way from interstitial cells of Cajal (ICC), via interstitial Cajal-like cells (ICLC) to TELOCYTES. J Cell Mol Med. 2010;14(4):729–40.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Popescu LM, Andrei F, et al. Snapshots of mammary gland interstitial cells: methylene-blue vital staining and c-kit immunopositivity. J Cell Mol Med. 2005;9(2):476–7.

    Article  CAS  PubMed  Google Scholar 

  9. Popescu LM, Hinescu ME, et al. Interstitial cells of Cajal in pancreas. J Cell Mol Med. 2005;9(1):169–90.

    Article  CAS  PubMed  Google Scholar 

  10. Suciu L, et al. Cardiac telocytes: serial dynamic images in cell culture. J Cell Mol Med. 2010;14(11):2687–92.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

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Correspondence to Mihnea Ioan Nicolescu MD, DMD, OMS, PhD, MSc .

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© 2016 Springer Science+Business Media Singapore

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Nicolescu, M.I. (2016). Telocytes in Exocrine Glands Stroma. In: Wang, X., Cretoiu, D. (eds) Telocytes. Advances in Experimental Medicine and Biology, vol 913. Springer, Singapore. https://doi.org/10.1007/978-981-10-1061-3_11

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