Abstract
This is chapter provides a detailed discussion of the clinical effects of common acid-base disorders encountered by the physician. It contains little discussion on the pathophysiology of these disorders as this is more than adequately covered in other texts. The physiological changes decribed are the unmodified changes produced by these disorders, and as such are not always observed. For this reason, the chapter on factors modifying the manifestations of acid-base disorders has preceded this chapter, and this chapter should be read in conjunction with the preceding chapter [chapter 13.2].
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References
Diem, K., Lentner, C., (eds.), (1968), “Wissenschaftliche tabellen”, 7th edn., pub. CIBA-GEIGY AG, Basel.
Hill, G.L., et al., (1976), Decreased trypsin and bile acids in ileal fistula drainage during the administration of a chemically defined liquid elemental diet. BRITISH JOURNAL OF SURGERY, 63, 133–136.
Hodgkin, J.E., et al., (1980), Incidence of metabolic alkalemia in hospitalized patients. CRITICAL CARE MEDICINE, 8, 725–728.
Mithoefer, J.C., et al., (1968), Effect of intravenous NaHCO3 on ventilation and gas exchange in normal man. RESPIRATION PHYSIOLOGY, 4, 132–140.
Grigor, K.C., et al., (1971), The effect of acetazolamide on postperfusion metabolic alkalosis. BRITISH JOURNAL OF ANAESTHESIA, 43, 352–361.
Waddell, W.J., Bates, R.J., (1969), Intracellular pH. PHYSIOLOGICAL REVIEWS, 49, 285–329.
Poole-Wilson, P.A., Cameron, I.R., (1975), Intracellular pH and K+ of cardiac and skeletal muscle in acidosis and alkalosis. AMERICAN JOURNAL OF PHYSIOLOGY, 229, 1305–1310.
Khambatta, H.J., Sullivan, S.F., (1973), Effects of respiratory alkalosis on oxygen consumption and oxygenation. ANESTHESIOLOGY, 38, 53–58.
Rastegar, H., et al., (1979), Respiratory alkalosis increases tissue oxygen demand. JOURNAL OF SURGICAL RESEARCH, 26, 687–692.8.
Alexander, S.C., et al., (1965), Cerebral carbohydrate metabolism during hypocarbia in man. Studies during nitrous oxide anesthesia. ANESTHESIOLOGY, 26, 624–632.
Alexander, S.C., et al., (1968), Cerebral carbohydrate metabolism in man during respiratory and metabolic alakalosis. JOURNAL OF APPLIED PHYSIOLOGY, 24, 66–72.
Relman, A.S., (1972), Metabolic consequences of acid-base disorders. KIDNEY INTERNATIONAL, 1, 347–359.
Bradley, R.D., Semple, S.J.G., (1962), A comparison of certain acid-base characteristics of arterial blood, jugular venous blood and cerebrospinal fluid in man, and the effect on them of some acute and chronic acid-base disturbances. JOURNAL OF PHYSIOLOGY (LONDON), 160, 381–391.
Davies, D.G., Nolan, W.F., (1982), Cerebral interstitial fluid acid-base status follows arterial acid-base perturbations. JOURNAL OF APPLIED PHYSIOLOGY, 53, 1551–1555.
Euler, von U.S., Lishajko, F., (1963), Influence of pH on uptake and release of noradenaline in adrenergic nerve granules. JOURNAL OF NEUROCHEMISTRY, 10, 145–149.
Nahas, G.G., et al., (1967), Acidemia and catecholamine output in the isolated canine adrenal gland. J AMERICAN JOURNAL OF PHYSIOLOGY, 213, 1186–1192.
Tenney, S.M., (1956), Sympatho-adrenal stimulation by carbon dioxide and the inhibitory effect of carbonic acid on epinephrine response. AMERICAN JOURNAL OF PHYSIOLOGY, 187, 341–346.
Darby, T.D., Watts, D.T., (1964), Acidosis and blood epinephrine levels in hemorrhagic hypotension. AMERICAN JOURNAL OF PHYSIOLOGY, 206, 1281–1284.
Fiorica, V., et al., (1969), Influence of blood pH on adrenomedullary response to hemorrhage. AMERICAN JOURNAL OF PHYSIOLOGY, 217, 1211–1215.
Bendixen, H.H., et al., (1963), Influence of respiratory acidosis on circulatory effect of epinephrine in dogs. CIRCULATION RESEARCH, 13, 64–70.
Schroeder, J.S., et al., (1970), Effects of respiratory acidosis on circulatory response to isoproterenol. AMERICAN JOURNAL OF PHYSIOLOGY, 218, 448–452.
Yakaitis, R.W., et al., (1978), Effects of catecholamines during respiratory alkalosis in dogs. JOURNAL OF APPLIED PHYSIOLOGY, 44, 581–584.
Hassan, H., et al., (1979), Hypercapnia and hyperkalemia. ANAESTHESIA, 34, 897–889.
Edwards, R., et al., (1977), Acute hypocapneic hypokalemia: An iatrogenic anesthetic complication. ANESTHESIA AND ANALGESIA, 56, 786–792.
Orringer, C.E., et al., (1977), Natural history of lactic acidosis after grand-mal seizures. A model for the srudyl of an anion-gap acidosis not associated with hyperkalemia. NEW ENGLAND JOURNAL OF MEDICINE, 297, 796–799.
Fulop, M., (1979), Serum potassium in lactic acidosis and ketoacidosis. NEW ENGLAND JOURNAL OF MEDICINE, 300, 1087–1089.
Wilson, R.F., et al., (1972), Severe alkalosis in critically ill surgical patients. ARCHIVES OF SURGERY, 105, 197–203.
Vaughan-Williams, E.M., Whyte, J.M., (1967), Chemosensitivity of cardiac muscle. JOURNAL OF PHYSIOLOGY (LONDON), 189, 119–137.
Campbell, G.S., (1955), Cardiac arrest: Further studies on the effect of pH changes on vagal inhibition of the heart. SURGERY, 38, 615–634.
Gerst, P.H., et al., (1966), A quantitative evaluation of the effects of acidosis and alkalosis upon the ventricular fibrillation threshold. SURGERY, 59, 1050–1060.
Katz, A.M., (1973), Effects of ischaemia on the contractile processes of heart muscle. AMERICAN JOURNAL OF CARDIOLOGY, 32, 456–460.
Poole-Wilson, P.A., Langer, G.A., (1979), Effects of acidosis on mechan ical function and Ca2+ exchange in rabbit myocardium. AMERICAN JOURNAL OF PHYSIOLOGY, 236, H525–H533.
Nahas, G.G., Cavert, H.M., (1957), Cardiac depressant effect of CO2 and its reversal. AMERICAN JOURNAL OF PHYSIOLOGY, 190, 483–491.
Bos, van den, G.C., et al., (1979), Effect of carbon dioxide on myocardial contractile performance, blood flow and oxygen consumption. JOURNAL OF PHYSIOLOGY (LONDON), 287, 149–161.
Clancy, R.L., et al., (1967), Influence of sodium bicarbonate on myocardial performance. AMERICAN JOURNAL OF PHYSIOLOGY, 212, 917–923.
Wead, W.B., Little, R.C., (1967), Effect of hypocapnia and respiratory alkalosis on cardiac contractility. PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY & MEDICINE, 126, 606–609.
Poole-Wilson, P.A., (1982), Acidosis and contractility of heart muscle. CIBA FOUNDATION SYMPOSIUM, 87, 58–76.
Steinhart, C.R., et al., (1983), β-adenergic activity and cardiovascular response to severe respiratory acidosis. AMERICAN JOURNAL OF PHYSIOLOGY, 244, H46–H54.
Frumin, M J., et al., (1959), Apneic oxygenation in man. ANESTHESIOLOGY, 20, 789–798.
Wollman, H., et al., (1968), Effects of extremes of respiratory and metabolic alkalosis on cerebral blood flow in man. JOURNAL OF APPLIED PHYSIOLOGY, 24, 60–65.
Cullen, D.J., Eger, E.I., (1974), Cardiovascular effects of carbon dioxide in man. ANESTHESIOLOGY, 41, 345–349.
Kittle, C.F., et al., (1965), The role of pH and CO2 in the distribution of blood flow. SURGERY, 57, 139–153.
Richardson, D.W., et al., (1972), Systemic circulatory responses to hypocapnia in man. AMERICAN JOURNAL OF PHYSIOLOGY, 223, 1308–1312.
Ainslie, S.G., et al., (1979), Fentanyl concentrations in brain and serum during respiratory acid-base changes in the dog. ANESTHESIOLOGY, 51, 293–297.
Schulman, D.S., et al., (1984), Blood pH and brain uptake of C14 morphine. ANESTHESIOLOGY, 61, 540–543.
Tuller, M.A., Mehdi, F., (1971), Compensatory hypoventilation and hypercapnia in primary metabolic alkalosis. AMERICAN JOURNAL OF MEDICINE, 50, 281–290.
Kety, S.S., Schmidt, C.F., (1946), The effects of acive and passive hyperventilation on cerebral blood flow, cerebral oxygen consumption, cardiac output, and blood pressure of normal young men. JOURNAL OF CLINICAL INVESTIGATION, 25, 107–119.
Edmondson, J.W., et al., (1976), Tetany: Quantitative interrelationships between calcium and alkalosis. AMERICAN JOURNAL OF PHYSIOLOGY, 228, 1082–1086.
Rotheram, E.B., et al., (1964), CNS disorder during mechanical ventilation in chronic pulmonary disease. JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 189, 993–997.
Kilburn, K.H., (1966), Shock, seizures and coma with alkalosis during mechanical ventilation. ANNALS OF INTERNAL MEDICINE, 65, 977–984.
Mudge, G.H., (1966), Influence of plasma composition on sodium excretion and diuretic action. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 139, 304–311.
Williams, D.B., Lyons, J.H. (1980), Treatment of severe metabolic alkalosis with intravenous solution of hydrochloric acid. SURGERY, GYNECOLOGY & OBSTETRICS, 150, 315–321.
Harkeny, A.H., et al., (1975), Hydrochloric acid in the correction of metabolic alkalosis. ARCHIVES OF SURGERY, 110,819–821.
Berthelson, P., et al., (1986), Dissociation of renal and respiratory effects of acetazolamide in the critcally ill. BRITISH JOURNAL OF ANAESTHESIA, 58, 512–516.
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© 1988 Kluwer Academic Publishers
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Woerlee, G.M. (1988). Clinical Acid-Base Disorders. In: Common Perioperative Problems and the Anaesthetist. Developments in Critical Care Medicine and Anesthesiology, vol 18. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1323-3_80
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DOI: https://doi.org/10.1007/978-94-009-1323-3_80
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-7089-8
Online ISBN: 978-94-009-1323-3
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