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The Use of GnRH Analogues to Control Menstrual Bleeding

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Abstract

A substantial proportion of General Practitioner consultations and gynaecological referrals concern disorders of menstrual bleeding. In the last decade an increased understanding of the mechanisms which initiate and regulate menstrual blood flow have resulted in new approaches to endeavour to control excessive or disordered menstrual bleeding.

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References

  1. Markee, JE (1940). Menstruation in intraocular endometrial transplants in the rhesus monkey. Contr Embryol Cam Ins, 28, 219

    Google Scholar 

  2. Pickles, VR, and Hall, WJ (1963). Some physiological properties of the menstrual stimulant substances Al and A2. J Reprod Fertil, 6, 315

    Article  PubMed  CAS  Google Scholar 

  3. Abel, M (1979). Production of prostaglandins by the human uterus: are they involved in menstruation? Res Clinic Forums, 1, 33

    CAS  Google Scholar 

  4. Smith, SK, Abel, MH, Kelly, RW, and Baird, DT (1981). Prostaglandin synthesis in the endometrium of women with ovular dysfunctional uterine bleeding. Brit Obstet Gynaecol, 88, 434

    Article  CAS  Google Scholar 

  5. Hamberg, M, and Samuellsson B (1974). Prostaglandin endoperoxides. Novel transformations of arachidonic acid in human platelets. Proc Natl Acad Sci USA, 71, 3400

    Article  PubMed  CAS  Google Scholar 

  6. Frser, HM, Laird, NC, and Blakeley, DM (1980). Decreased pituitary responsiveness and inhibition of the luteinizing hormone surge and ovulation in the stumptailed monkey (Macaca arrctoides) by chronic treatment with an agonist of luteinizing hormone-releasing hormone. Endocrinology, 115, 1780

    Google Scholar 

  7. Bergquist, C, Nillius, SJ, and Wide, L (1982). Long-term intranasal luteinizing hormone-releasing hormone agonist treatment for contraception in women. Fertil Steril, 38, 190

    PubMed  CAS  Google Scholar 

  8. Schmidt-Gollwitzer, M, Hardt, W, Schmidt-Gollwitzer, K, Von der Ohne, M, and Nevinny-Stickel, J (1981). Influence of the LH-RH analogue buserelin on cyclic ovarian function and on endometrium. A new approach to fertility control? Contraception, 23, 187

    CAS  Google Scholar 

  9. Pedroza E, Vilchez-Martinez, JA, Coy, DH, Arimura, A, and Schally, AV (1978). Correlation between in vivo inhibition of gonadotrophin release induced by LHRH and the blockade of ovulation by synthetic analogues of LHRH. Int J Fertil, 23, 294

    PubMed  CAS  Google Scholar 

  10. Frser, HM, and Shaw, RW (1984). Effects of chronic luteinizing hormone-releasing hormone agonist treatment in dysfunctional uterine bleeding in the stumptailed macaque. Acta Endocrinol, 106, 381

    Google Scholar 

  11. Bergquist, C, Nillius, SJ, Wide, L, and Lindgren, A (1981). Endometrial patterns in women on chronic luteinizing hormone-releasing hormone agonist treatment for contraception. Fertil Steril, 36, 339

    PubMed  CAS  Google Scholar 

  12. Hallberg, L, and Nilsson, L (1964). Determination of menstrual blood loss. Scand J Clin Lab Invest, 16, 244

    Article  PubMed  CAS  Google Scholar 

  13. Shaw, RW, Fraser, HM, and Boyle, H (1983). Intranasal LHRH agonist treatment in women with endometriosis. Brit Med J, 287, 1667

    Article  CAS  Google Scholar 

  14. Matta, WH, Shaw, RW, Hesp, R, and Katz, D (1987). Hypogonadism induced by luteinizing hormone releasing hormone agonist analogues: effects on bone density in pre-menopausal women. Brit Med J, 294, 1523

    Article  CAS  Google Scholar 

  15. Matta, WH, Stabile, I, Shaw, RW, and Campbell, S (1988). Doppler assessment of uterine blood flow changes in patients with fibroids receiving the gonadotrophin-releasing hormone agonist buserelin. Fertil Steril (in press)

    Google Scholar 

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B. H. Vickery B. Lunenfeld

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© 1990 Kluwer Academic Publishers

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Shaw, R.W. (1990). The Use of GnRH Analogues to Control Menstrual Bleeding. In: Vickery, B.H., Lunenfeld, B. (eds) GnRH Analogues in Reproduction and Gynecology. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0721-8_7

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  • DOI: https://doi.org/10.1007/978-94-009-0721-8_7

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6809-3

  • Online ISBN: 978-94-009-0721-8

  • eBook Packages: Springer Book Archive

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